SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3prx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 ALA B 791
VAL B 578
TRP B 757
 None
 0.88A 1av2C-3prxB:
undetectable
1av2D-3prxB:
undetectable		 1av2C-3prxB:
1.67
1av2D-3prxB:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 THR B 543
THR B 511
GLY B 457
ASP B 458
 None
 0.98A 1bu5A-3prxB:
undetectable		 1bu5A-3prxB:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 THR B 543
THR B 511
GLY B 457
ASP B 458
 None
 0.99A 1bu5B-3prxB:
undetectable		 1bu5B-3prxB:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 ARG B 948
VAL B1303
ILE B1288
THR B 961
ILE B 963
 None
 0.92A 1c6yA-3prxB:
undetectable		 1c6yA-3prxB:
4.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.61A 1dvtA-3prxB:
2.1
1dvtB-3prxB:
3.6		 1dvtA-3prxB:
6.45
1dvtB-3prxB:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.68A 1dvxA-3prxB:
3.5		 1dvxA-3prxB:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.67A 1dvxB-3prxB:
3.6		 1dvxB-3prxB:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 869
ILE B 835
HIS B 837
 None
 0.64A 1fm9A-3prxB:
undetectable		 1fm9A-3prxB:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 LEU B1464
LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.77A 1ictA-3prxB:
undetectable
1ictC-3prxB:
3.6		 1ictA-3prxB:
6.13
1ictC-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.78A 1ictB-3prxB:
3.6		 1ictB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.60A 1ictD-3prxB:
2.0		 1ictD-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 869
ILE B 835
HIS B 837
 None
 0.60A 1k74A-3prxB:
undetectable		 1k74A-3prxB:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 LEU B 280
LEU B 264
SER B 317
 None
 0.59A 1tlmA-3prxB:
undetectable		 1tlmA-3prxB:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.70A 1tyrA-3prxB:
4.3		 1tyrA-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 ALA B 791
VAL B 578
TRP B 757
 None
 0.85A 1w5uC-3prxB:
undetectable
1w5uD-3prxB:
undetectable		 1w5uC-3prxB:
1.67
1w5uD-3prxB:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 ILE B1367
PHE B1440
LEU B1400
ILE B1408
 None
 0.92A 2azxA-3prxB:
undetectable		 2azxA-3prxB:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 LEU B1273
SER B 175
LEU B1298
ASN B1296
ARG B1301
 None
 1.35A 2ceoB-3prxB:
undetectable		 2ceoB-3prxB:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 4 ASP B1318
ASP B 931
ASP B1276
GLY B 936
 None
 1.36A 2igtC-3prxB:
undetectable		 2igtC-3prxB:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 TRP B 757
ALA B 791
VAL B 578
 None
 0.76A 2izqA-3prxB:
undetectable
2izqB-3prxB:
undetectable		 2izqA-3prxB:
1.67
2izqB-3prxB:
1.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2N27_A_4DYA205_1
(CALMODULIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 LEU B1573
THR B1602
ILE B1607
MET B1542
LEU B 887
 None
 1.26A 2n27A-3prxB:
undetectable		 2n27A-3prxB:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 MET B 321
ILE B1381
PRO B 222
SER B 223
 None
 1.33A 2qd3B-3prxB:
undetectable		 2qd3B-3prxB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 221
LYS B 753
TYR B 822
LYS B 911
 None
 1.31A 2w98A-3prxB:
undetectable
2w98B-3prxB:
undetectable		 2w98A-3prxB:
13.01
2w98B-3prxB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LYS B 753
TYR B 822
LEU B 891
LYS B 911
 None
 1.49A 2w98A-3prxB:
undetectable
2w98B-3prxB:
undetectable		 2w98A-3prxB:
13.01
2w98B-3prxB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 ARG B 250
SER B1409
VAL B 329
VAL B 257
 None
 1.04A 2y05A-3prxB:
undetectable
2y05B-3prxB:
undetectable		 2y05A-3prxB:
12.42
2y05B-3prxB:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 ILE B 283
ALA B 249
GLY B 288
GLY B 290
LEU B 252
 None
 0.92A 2y7hB-3prxB:
undetectable		 2y7hB-3prxB:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 ILE B 283
ALA B 249
GLY B 288
GLY B 290
LEU B 252
 None
 0.92A 2y7hC-3prxB:
undetectable		 2y7hC-3prxB:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 PHE B1343
TYR B1371
VAL B1430
PHE B 262
LEU B 280
 None
 1.35A 3apvB-3prxB:
undetectable		 3apvB-3prxB:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.78A 3cfqA-3prxB:
3.6		 3cfqA-3prxB:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.79A 3cfqA-3prxB:
3.6
3cfqB-3prxB:
3.5		 3cfqA-3prxB:
5.58
3cfqB-3prxB:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLU B  44
HIS B  46
THR B 480
 None
 0.86A 3hkuA-3prxB:
undetectable		 3hkuA-3prxB:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 4 PRO B1453
TYR B1472
GLY B1479
THR B1478
 None
 1.43A 3ib0A-3prxB:
undetectable		 3ib0A-3prxB:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 ALA B 791
VAL B 578
TRP B 757
 None
 0.73A 3l8lA-3prxB:
undetectable
3l8lB-3prxB:
undetectable		 3l8lA-3prxB:
1.67
3l8lB-3prxB:
2.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 ILE B 844
ALA B 903
PHE B 814
LEU B 836
VAL B 846
 None
 1.08A 3n0hA-3prxB:
undetectable		 3n0hA-3prxB:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 ALA B 573
SER B 793
VAL B 575
LEU B 762
 None
 0.81A 3o14A-3prxB:
4.7		 3o14A-3prxB:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.79A 3ozkB-3prxB:
2.6		 3ozkB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 ILE B 844
ALA B 903
PHE B 814
LEU B 836
VAL B 846
 None
 1.07A 3s3vA-3prxB:
undetectable		 3s3vA-3prxB:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 GLY B 614
VAL B 620
ASP B 623
THR B 610
 None
 1.03A 3vqrA-3prxB:
undetectable		 3vqrA-3prxB:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 GLY B 614
VAL B 620
ASP B 623
THR B 610
 None
 1.05A 3vqrB-3prxB:
undetectable		 3vqrB-3prxB:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.60A 4d7bB-3prxB:
3.6		 4d7bB-3prxB:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.87A 4d7bA-3prxB:
3.5		 4d7bA-3prxB:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 PHE B 354
ILE B 433
ASP B 623
GLY B 614
ASN B 616
 None
 1.29A 4eb4A-3prxB:
undetectable		 4eb4A-3prxB:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 PHE B 354
ILE B 433
ASP B 623
GLY B 614
ASN B 616
 None
 1.28A 4eb4B-3prxB:
undetectable		 4eb4B-3prxB:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.62A 4i89A-3prxB:
3.5		 4i89A-3prxB:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.82A 4ik7B-3prxB:
3.5		 4ik7B-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.84A 4ikiB-3prxB:
3.5		 4ikiB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.84A 4ikjA-3prxB:
3.5
4ikjB-3prxB:
3.6		 4ikjA-3prxB:
6.13
4ikjB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.83A 4ikkA-3prxB:
undetectable
4ikkB-3prxB:
3.5		 4ikkA-3prxB:
6.13
4ikkB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.86A 4iklA-3prxB:
3.5
4iklB-3prxB:
3.6		 4iklA-3prxB:
6.13
4iklB-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 TYR B 213
ILE B 199
TYR B 210
ILE B 130
 None
 0.98A 4jtpA-3prxB:
undetectable		 4jtpA-3prxB:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.60A 4pwjB-3prxB:
3.5		 4pwjB-3prxB:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 SER B 174
GLU B 164
ILE B 199
ILE B 130
ARG B 198
 None
None
None
None
NAG  B2001 ( 4.6A)
 1.34A 4uroB-3prxB:
undetectable		 4uroB-3prxB:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.63A 5bojA-3prxB:
3.2		 5bojA-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 LEU B1345
VAL B1430
ILE B1425
LEU B1427
LEU B1365
 None
 1.19A 5ienB-3prxB:
undetectable		 5ienB-3prxB:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 ILE B1382
TYR B1459
VAL B1458
SER B1377
 None
 0.92A 5jwaH-3prxB:
undetectable		 5jwaH-3prxB:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 LEU B 567
ASP B 553
GLY B 552
ALA B 803
VAL B 789
 None
 1.41A 5kbwB-3prxB:
undetectable		 5kbwB-3prxB:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.58A 5l4iA-3prxB:
3.4		 5l4iA-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 GLY B 612
SER B 535
ASN B 617
LEU B 628
GLU B 622
 None
 1.25A 5nwwA-3prxB:
undetectable		 5nwwA-3prxB:
2.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 PHE B 354
ILE B 433
ASP B 623
GLY B 614
ASN B 616
 None
 1.35A 5x66D-3prxB:
undetectable		 5x66D-3prxB:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 LEU B 913
VAL B 915
PRO B 886
PHE B1471
THR B1478
 None
 1.38A 5xipD-3prxB:
undetectable		 5xipD-3prxB:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 869
ILE B 835
HIS B 837
 None
 0.56A 5z12B-3prxB:
undetectable		 5z12B-3prxB:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 VAL B 200
THR B 211
PHE B 214
LEU B 188
VAL B 143
 None
 1.24A 6a93B-3prxB:
undetectable		 6a93B-3prxB:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 TYR B1522
HIS B1561
MET B1542
 None
 1.23A 6af6A-3prxB:
undetectable		 6af6A-3prxB:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B1511
TRP B1584
VAL B1523
 None
 0.88A 6auuA-3prxB:
undetectable		 6auuA-3prxB:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLY B 325
THR B 322
GLU B 323
 None
 0.31A 6b58A-3prxB:
undetectable		 6b58A-3prxB:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 TYR B 360
ASP B 534
VAL B 447
ALA B 432
 None
 1.22A 6djzB-3prxB:
2.4		 6djzB-3prxB:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3prx COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU B 120
ALA B 641
SER B 122
THR B  96
 None
 1.03A 6f88A-3prxB:
undetectable		 6f88A-3prxB:
4.31