SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ps0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 4 VAL A  62
PHE A  81
SER A  76
VAL A  72
 None
 1.45A 1e7cA-3ps0A:
undetectable		 1e7cA-3ps0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 8 SER A  60
TYR A  57
LEU A 318
LEU A 314
 None
 0.87A 2bfpB-3ps0A:
undetectable		 2bfpB-3ps0A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 6 LEU A 183
PRO A 144
LEU A  15
LEU A  12
 None
 1.11A 3q1eA-3ps0A:
undetectable
3q1eC-3ps0A:
undetectable		 3q1eA-3ps0A:
15.51
3q1eC-3ps0A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 7 ALA A 118
ILE A 117
ARG A 218
GLY A  73
 None
 0.96A 3v4tH-3ps0A:
undetectable		 3v4tH-3ps0A:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 8 ARG A 147
GLU A 300
ILE A 299
ASP A 268
 None
 0.92A 4d33A-3ps0A:
undetectable		 4d33A-3ps0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 7 ARG A 147
GLU A 300
ILE A 299
ASP A 268
 None
 0.99A 4d33B-3ps0A:
undetectable		 4d33B-3ps0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 8 ARG A 147
GLU A 300
ILE A 299
ASP A 268
 None
 1.02A 4d39A-3ps0A:
undetectable		 4d39A-3ps0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 7 ARG A 147
GLU A 300
ILE A 299
ASP A 268
 None
 0.96A 4d39B-3ps0A:
undetectable		 4d39B-3ps0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		4 / 8 PHE A 186
ALA A  54
LEU A 139
GLY A 140
 None
 0.87A 4xk8a-3ps0A:
undetectable		 4xk8a-3ps0A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		5 / 12 VAL A  62
LEU A  61
ILE A 117
GLY A 121
LEU A 139
 None
 0.96A 4y8wA-3ps0A:
undetectable		 4y8wA-3ps0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2
(Sulfolobus
solfataricus) 		5 / 12 VAL A  62
LEU A  61
ILE A 117
GLY A 121
LEU A 139
 None
 0.94A 4y8wB-3ps0A:
undetectable		 4y8wB-3ps0A:
20.45