SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3psg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 8 PHE A  56
GLY A 102
VAL A 136
PHE A  27
 None
 1.02A 1gsfC-3psgA:
undetectable		 1gsfC-3psgA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 THR A 283
GLU A 287
ASP A 290
 None
 0.74A 1nt2A-3psgA:
undetectable		 1nt2A-3psgA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 303
GLY A  34
VAL A 153
ILE A 306
 None
 0.95A 1t3rB-3psgA:
5.5		 1t3rB-3psgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 ASP A 149
ARG A 315
ASP A 142
 None
 0.82A 1vptA-3psgA:
undetectable		 1vptA-3psgA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 5 LEU A 155
ASP A 303
VAL A 153
ILE A 306
 None
 1.01A 2aoiB-3psgA:
5.5		 2aoiB-3psgA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 8 VAL A 165
VAL A 153
LEU A 123
THR A  33
 None
 0.92A 2gehA-3psgA:
undetectable		 2gehA-3psgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
ILE A  73
ILE A 120
 None
 0.69A 2pynB-3psgA:
5.8		 2pynB-3psgA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
ILE A  73
ILE A 120
 None
 0.64A 2q64B-3psgA:
5.7		 2q64B-3psgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
ILE A  73
ILE A 120
 None
 0.63A 2qakA-3psgA:
5.7		 2qakA-3psgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASN A  37
ILE A  73
ILE A 120
 None
 0.70A 2qakB-3psgA:
5.7		 2qakB-3psgA:
18.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		7 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  75
PHE A 117
ASP A 215
GLY A 217
 None
 0.56A 2v0zC-3psgA:
39.0		 2v0zC-3psgA:
36.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ALA A 115
PHE A 117
GLY A 217
 None
 0.82A 2v0zO-3psgA:
39.2		 2v0zO-3psgA:
36.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
GLY A 217
SER A 219
 None
 0.73A 2v0zO-3psgA:
39.2		 2v0zO-3psgA:
36.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
PHE A 117
ASP A 215
GLY A 217
 None
 0.56A 2v0zO-3psgA:
39.2		 2v0zO-3psgA:
36.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 VAL A 165
VAL A 153
LEU A 123
THR A  33
VAL A 136
 None
 1.23A 3czvA-3psgA:
undetectable
3czvB-3psgA:
undetectable		 3czvA-3psgA:
21.18
3czvB-3psgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 LEU A 155
ASP A 303
GLY A  34
VAL A 153
ILE A 306
 None
 1.05A 3d20A-3psgA:
5.7		 3d20A-3psgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 4 ARG A 315
ASP A 142
ASP A 138
PRO A 126
 None
 1.30A 3fgrB-3psgA:
undetectable		 3fgrB-3psgA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 4 ARG A 315
ASP A 142
ASP A 138
PRO A 135
 None
 1.41A 3fgrB-3psgA:
undetectable		 3fgrB-3psgA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAM_A_LLLA500_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 SER A 129
ASN A  37
ASP A 138
ASP A 142
TYR A  86
 None
 1.19A 3hamA-3psgA:
undetectable		 3hamA-3psgA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3psg PEPSINOGEN
(Sus
scrofa) 		6 / 10 VAL A 153
PHE A 305
ILE A 306
ILE A 192
VAL A 320
VAL A 214
 None
 1.50A 3me6A-3psgA:
undetectable		 3me6A-3psgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 VAL A 304
SER A 219
LEU A 276
 None
 0.74A 3n8xA-3psgA:
undetectable		 3n8xA-3psgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ASP A  32
GLY A  34
ASP A 215
THR A 218
ILE A 300
 None
 0.71A 3prsA-3psgA:
34.7		 3prsA-3psgA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 8 GLY A  34
SER A  35
TYR A  75
ASP A 215
 None
 0.43A 3pwwA-3psgA:
34.7		 3pwwA-3psgA:
29.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.49A 3q70A-3psgA:
7.9		 3q70A-3psgA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
THR A 218
 None
 0.65A 3q70A-3psgA:
7.9		 3q70A-3psgA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 3psg PEPSINOGEN
(Sus
scrofa) 		6 / 12 ILE A 213
ASP A 215
GLY A 217
SER A  35
ASP A  32
ILE A 120
 None
 1.16A 3q70A-3psgA:
7.9		 3q70A-3psgA:
31.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 THR A  12
ILE A  73
TYR A  75
THR A 218
 None
 1.03A 3q70A-3psgA:
7.9		 3q70A-3psgA:
31.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.41A 3tneA-3psgA:
33.6		 3tneA-3psgA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.69A 3tneA-3psgA:
33.6		 3tneA-3psgA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A  30
ASP A  32
GLY A  34
ASP A 215
ILE A 300
 None
 0.42A 3tneB-3psgA:
33.5		 3tneB-3psgA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A 213
ASP A 215
GLY A 217
ASP A  32
ILE A 120
 None
 0.71A 3tneB-3psgA:
33.5		 3tneB-3psgA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 5 TYR A   9
SER A  36
ASP A 215
ASP A 303
ILE A 306
 None
 1.42A 3uj7B-3psgA:
undetectable		 3uj7B-3psgA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 PHE A 151
VAL A 153
ILE A 306
ILE A  18
VAL A 214
 None
 1.27A 4a97B-3psgA:
undetectable
4a97C-3psgA:
undetectable		 4a97B-3psgA:
21.96
4a97C-3psgA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 ARG A  13
GLU A  13
LEU A 276
ASP A  11
 None
 1.20A 4cevA-3psgA:
undetectable
4cevB-3psgA:
undetectable		 4cevA-3psgA:
21.24
4cevB-3psgA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 ASP A  11
ARG A  13
GLU A  13
LEU A 276
 None
 1.17A 4cevA-3psgA:
undetectable
4cevC-3psgA:
undetectable		 4cevA-3psgA:
21.24
4cevC-3psgA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 ARG A  13
GLU A  13
LEU A 276
ASP A  11
 None
 1.20A 4cevD-3psgA:
undetectable
4cevE-3psgA:
undetectable		 4cevD-3psgA:
21.24
4cevE-3psgA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 ARG A  13
GLU A  13
LEU A 276
ASP A  11
 None
 1.18A 4cevE-3psgA:
undetectable
4cevF-3psgA:
undetectable		 4cevE-3psgA:
21.24
4cevF-3psgA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 LEU A 155
ASP A 303
GLY A  34
VAL A 153
ILE A 306
 None
 0.93A 4dqbA-3psgA:
5.8		 4dqbA-3psgA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 303
GLY A  34
VAL A 153
ILE A 306
 None
 0.96A 4dqeA-3psgA:
5.7		 4dqeA-3psgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 11 LEU A 155
ASP A 303
GLY A  34
VAL A 153
ILE A 306
 None
 0.96A 4dqhA-3psgA:
5.6		 4dqhA-3psgA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 PHE A 117
ALA A 115
PRO A   5
LEU A 112
 None
 1.03A 4dtzB-3psgA:
undetectable		 4dtzB-3psgA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 6 PHE A 117
ALA A 115
PRO A   5
LEU A 112
 None
 0.93A 4dubB-3psgA:
undetectable		 4dubB-3psgA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 ASP A 149
ARG A 315
ASP A 142
 None
 0.75A 4fp9D-3psgA:
undetectable		 4fp9D-3psgA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 ASP A 149
ARG A 315
ASP A 142
 None
 0.75A 4fzvA-3psgA:
undetectable		 4fzvA-3psgA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 5 ILE A  30
ASN A   8
TYR A  75
ILE A 120
 None
 1.01A 4jtpA-3psgA:
undetectable		 4jtpA-3psgA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.67A 4k8cA-3psgA:
undetectable		 4k8cA-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.66A 4kahA-3psgA:
undetectable		 4kahA-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.66A 4kahB-3psgA:
undetectable		 4kahB-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.66A 4kanA-3psgA:
undetectable		 4kanA-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.68A 4kanB-3psgA:
undetectable		 4kanB-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.69A 4kbeA-3psgA:
undetectable		 4kbeA-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.66A 4kbeB-3psgA:
undetectable		 4kbeB-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.67A 4lbgA-3psgA:
undetectable		 4lbgA-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 SER A  35
TYR A  75
PRO A 135
 None
 0.66A 4lbgB-3psgA:
undetectable		 4lbgB-3psgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 ASP A 215
ASP A  32
ASN A  37
 None
 0.68A 4q5mA-3psgA:
8.5		 4q5mA-3psgA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 7 TYR A 309
ALA A 273
ILE A 258
LEU A 221
 None
 0.79A 4uymB-3psgA:
undetectable		 4uymB-3psgA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3psg PEPSINOGEN
(Sus
scrofa) 		4 / 5 PRO A   5
HIS A  53
LEU A  38
PHE A  15
 None
 1.42A 5igjA-3psgA:
undetectable		 5igjA-3psgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3psg PEPSINOGEN
(Sus
scrofa) 		3 / 3 ASP A  11
ASN A   8
PHE A 286
 None
 0.78A 5jglB-3psgA:
undetectable		 5jglB-3psgA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3psg PEPSINOGEN
(Sus
scrofa) 		5 / 12 ILE A 275
SER A 251
LEU A 221
PHE A 286
ASP A 257
 None
 1.41A 6dwnB-3psgA:
undetectable		 6dwnB-3psgA:
13.86