SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3psh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 4 ILE A 165
MET A 303
VAL A  44
GLY A 164
 None
 1.41A 1e06B-3pshA:
undetectable		 1e06B-3pshA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 8 GLU A 305
ILE A  52
THR A  49
PRO A 302
LEU A 135
 None
 1.45A 1hmyA-3pshA:
undetectable		 1hmyA-3pshA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 GLU A 118
GLN A 122
VAL A 109
LEU A 101
PRO A  90
 None
 1.15A 1oq5A-3pshA:
undetectable		 1oq5A-3pshA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 8 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.74A 1rtsA-3pshA:
undetectable		 1rtsA-3pshA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 8 ALA A 156
THR A 151
THR A 149
LYS A 221
 None
 0.94A 2kotB-3pshA:
undetectable		 2kotB-3pshA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		3 / 3 LYS A  75
ARG A  79
VAL A  78
 None
 1.01A 2r2vC-3pshA:
undetectable
2r2vD-3pshA:
undetectable		 2r2vC-3pshA:
11.44
2r2vD-3pshA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 9 TYR A 340
LEU A 181
LEU A 161
LEU A 307
ALA A 306
 None
 1.19A 2vcvD-3pshA:
undetectable		 2vcvD-3pshA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 9 TYR A 340
LEU A 181
LEU A 161
LEU A 307
ALA A 306
 None
 1.17A 2vcvE-3pshA:
undetectable		 2vcvE-3pshA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 9 TYR A 340
LEU A 181
LEU A 161
LEU A 307
ALA A 306
 None
 1.15A 2vcvH-3pshA:
undetectable		 2vcvH-3pshA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 9 TYR A 340
LEU A 181
LEU A 161
LEU A 307
ALA A 306
 None
 1.18A 2vcvI-3pshA:
undetectable		 2vcvI-3pshA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 GLY A 178
LEU A 181
ILE A  52
ALA A 185
LEU A 135
 None
 1.00A 3gwvA-3pshA:
undetectable		 3gwvA-3pshA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 7 ASP A 347
ASP A 263
TYR A 265
PRO A 266
 None
 1.18A 3l2vA-3pshA:
undetectable		 3l2vA-3pshA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 GLY A 220
LYS A 221
GLY A 242
PRO A 148
 None
 1.01A 3onnA-3pshA:
3.3		 3onnA-3pshA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 7 ILE A  35
LYS A 174
PHE A 172
LYS A  60
 None
 0.98A 3sj0X-3pshA:
undetectable		 3sj0X-3pshA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 VAL A 251
LEU A 248
LEU A 214
ILE A 272
 None
 0.89A 4a9jA-3pshA:
undetectable		 4a9jA-3pshA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 VAL A 251
LEU A 248
LEU A 214
ILE A 272
 None
 0.76A 4a9jB-3pshA:
undetectable		 4a9jB-3pshA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 VAL A 251
LEU A 248
LEU A 214
ILE A 272
 None
 0.87A 4a9jC-3pshA:
undetectable		 4a9jC-3pshA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		3 / 3 PHE A 186
VAL A 182
GLU A 166
 None
 0.70A 4fvqA-3pshA:
undetectable		 4fvqA-3pshA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA405_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 ARG A 136
LEU A 150
LYS A 221
ASN A 147
 None
 1.38A 4ifxA-3pshA:
0.0		 4ifxA-3pshA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 ALA A 185
GLY A 310
ALA A 308
TYR A 336
TYR A 344
 None
 1.06A 4lg1A-3pshA:
undetectable		 4lg1A-3pshA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 ALA A 185
GLY A 310
ALA A 308
TYR A 336
TYR A 344
 None
 1.05A 4lg1B-3pshA:
undetectable		 4lg1B-3pshA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 ALA A 185
GLY A 310
ALA A 308
TYR A 336
TYR A 344
 None
 1.07A 4lg1C-3pshA:
undetectable		 4lg1C-3pshA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		3 / 3 ASN A  76
ASP A 263
ASP A 267
 None
 0.80A 4obwD-3pshA:
undetectable		 4obwD-3pshA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 8 LEU A 167
GLY A 164
GLU A 166
ALA A 156
 None
 0.65A 4rjdA-3pshA:
undetectable
4rjdB-3pshA:
undetectable		 4rjdA-3pshA:
12.54
4rjdB-3pshA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 7 LEU A  73
GLU A 305
THR A 342
VAL A  54
 None
 1.00A 4wnvD-3pshA:
undetectable		 4wnvD-3pshA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 LEU A 284
ALA A 283
THR A 216
ALA A 210
VAL A 269
 None
 1.20A 4x1iB-3pshA:
undetectable		 4x1iB-3pshA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA408_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 5 ARG A 136
LEU A 150
LYS A 221
ASN A 147
 None
 1.37A 4xdtA-3pshA:
0.0		 4xdtA-3pshA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 8 ALA A 257
LEU A 318
ALA A 232
LEU A 314
LEU A 260
 None
 1.08A 4z90A-3pshA:
undetectable
4z90B-3pshA:
undetectable
4z90C-3pshA:
undetectable
4z90D-3pshA:
undetectable
4z90E-3pshA:
undetectable		 4z90A-3pshA:
19.72
4z90B-3pshA:
19.72
4z90C-3pshA:
19.72
4z90D-3pshA:
19.72
4z90E-3pshA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 8 LEU A 314
LEU A 260
ALA A 257
LEU A 318
ALA A 232
 None
 1.08A 4z90A-3pshA:
undetectable
4z90B-3pshA:
undetectable
4z90C-3pshA:
undetectable
4z90D-3pshA:
undetectable
4z90E-3pshA:
undetectable		 4z90A-3pshA:
19.72
4z90B-3pshA:
19.72
4z90C-3pshA:
19.72
4z90D-3pshA:
19.72
4z90E-3pshA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 7 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.86A 5h3aA-3pshA:
undetectable		 5h3aA-3pshA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 10 LEU A  50
ILE A  62
ALA A  42
PHE A 172
PRO A 304
 None
 1.38A 5m0oA-3pshA:
undetectable		 5m0oA-3pshA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		3 / 3 TYR A 344
ALA A 296
TYR A 295
 None
 0.70A 5uunB-3pshA:
undetectable		 5uunB-3pshA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 7 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.81A 5x5qC-3pshA:
undetectable		 5x5qC-3pshA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 8 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.81A 5x5qD-3pshA:
undetectable		 5x5qD-3pshA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 6 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.82A 5x5qE-3pshA:
undetectable		 5x5qE-3pshA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 8 PHE A 172
ILE A 168
ASP A 179
GLY A 178
 None
 0.79A 5x5qF-3pshA:
undetectable		 5x5qF-3pshA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		4 / 6 TYR A 340
LEU A  50
GLU A  83
LEU A  84
 None
 1.30A 5xooA-3pshA:
undetectable		 5xooA-3pshA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3psh PROTEIN HI_1472
(Haemophilus
influenzae) 		5 / 12 GLN A 122
VAL A 109
VAL A 126
LEU A 101
PRO A  90
 None
 0.96A 6bccA-3pshA:
undetectable		 6bccA-3pshA:
12.93