SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3psi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 9 ASP A 797
ILE A 782
ALA A 764
ILE A 765
THR A 798
 None
 1.41A 1aj6A-3psiA:
undetectable		 1aj6A-3psiA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 738
SER A 752
ALA A 810
ILE A 750
 None
 1.04A 1fxhA-3psiA:
undetectable
1fxhB-3psiA:
2.7		 1fxhA-3psiA:
9.87
1fxhB-3psiA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_1
(DNA GYRASE SUBUNIT B)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 ASP A1111
ILE A 739
PRO A 740
ASP A 838
ILE A 747
 None
 1.28A 1kijB-3psiA:
undetectable		 1kijB-3psiA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 5 ASP A 358
VAL A 357
SER A 356
ASP A 412
 None
 1.24A 1n2xB-3psiA:
undetectable		 1n2xB-3psiA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 990
ALA A 994
TYR A1026
ILE A 999
 None
 1.23A 1oniH-3psiA:
undetectable
1oniI-3psiA:
undetectable		 1oniH-3psiA:
7.68
1oniI-3psiA:
7.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 574
VAL A 538
ILE A 682
ASP A 516
 None
 0.75A 1uwhA-3psiA:
undetectable		 1uwhA-3psiA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 962
LEU A 973
PHE A 954
SER A 932
 None
 1.37A 1wrkB-3psiA:
undetectable		 1wrkB-3psiA:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 ARG A1061
GLU A1062
GLN A1015
 None
 1.02A 2p16A-3psiA:
undetectable		 2p16A-3psiA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 765
PRO A 808
LEU A 831
ILE A 811
 None
 1.03A 2q83B-3psiA:
undetectable		 2q83B-3psiA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 848
ILE A 813
ASP A 851
SER A1123
 None
 1.15A 2xytI-3psiA:
undetectable		 2xytI-3psiA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 777
VAL A 768
CYH A 806
TYR A 780
 None
 1.37A 2xz5D-3psiA:
undetectable
2xz5E-3psiA:
undetectable		 2xz5D-3psiA:
10.74
2xz5E-3psiA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 450
ASP A 445
TYR A 472
 None
 0.78A 2yvlB-3psiA:
undetectable		 2yvlB-3psiA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 653
LYS A 624
VAL A 604
 None
 1.05A 3brfA-3psiA:
undetectable		 3brfA-3psiA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 836
ILE A 844
GLY A 812
TYR A 769
LEU A 799
 None
 1.28A 3elzC-3psiA:
undetectable		 3elzC-3psiA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 894
TYR A 891
ILE A 855
ALA A 854
LEU A 880
 None
 0.79A 3n8zB-3psiA:
undetectable		 3n8zB-3psiA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 888
LEU A 733
ALA A 892
ASN A 893
LEU A 894
 None
 0.84A 3r9cA-3psiA:
undetectable		 3r9cA-3psiA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 799
ALA A 767
ILE A 750
ILE A 803
ILE A 802
 None
 1.08A 3s53B-3psiA:
undetectable		 3s53B-3psiA:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 799
ALA A 767
ASP A 779
ILE A 750
ILE A 803
ILE A 802
 None
 1.35A 3s54B-3psiA:
undetectable		 3s54B-3psiA:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 735
PHE A1112
TYR A 883
 None
 0.78A 3ucjB-3psiA:
undetectable		 3ucjB-3psiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 735
PHE A1112
TYR A 883
 None
 0.82A 3ucjA-3psiA:
undetectable		 3ucjA-3psiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 989
GLY A 953
SER A 952
SER A 993
 None
 0.87A 3v7pA-3psiA:
undetectable		 3v7pA-3psiA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 10 ALA A1079
LEU A1028
LEU A1073
ASN A1074
ILE A1097
 None
 1.18A 3wdmB-3psiA:
undetectable		 3wdmB-3psiA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 SER A 917
THR A 731
ILE A 904
PHE A 729
HIS A 727
 None
 1.31A 4c49C-3psiA:
undetectable		 4c49C-3psiA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 SER A 917
THR A 731
ILE A 904
PHE A 729
HIS A 727
 None
 1.39A 4c49D-3psiA:
undetectable		 4c49D-3psiA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 383
THR A 382
ILE A 351
 None
 0.92A 4e0fB-3psiA:
undetectable		 4e0fB-3psiA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 9 ALA A 881
ALA A 810
ILE A 846
GLY A 812
ILE A 847
 None
 1.03A 4eatB-3psiA:
2.4		 4eatB-3psiA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 933
ALA A 945
SER A 993
LEU A 979
VAL A 935
 None
 1.49A 4kyaH-3psiA:
undetectable		 4kyaH-3psiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 846
ALA A 767
LEU A 751
LEU A 799
ILE A 782
 None
 1.14A 4lnwA-3psiA:
undetectable		 4lnwA-3psiA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 846
ALA A 767
LEU A 751
LEU A 799
ILE A 782
 None
 1.16A 4lnxA-3psiA:
undetectable		 4lnxA-3psiA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 378
LYS A 379
ILE A 374
ASN A 376
ALA A 373
 None
 1.49A 4ou1A-3psiA:
undetectable		 4ou1A-3psiA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1016
ASP A1025
ALA A1029
VAL A1032
 None
 0.92A 4zbqA-3psiA:
2.0		 4zbqA-3psiA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 989
ILE A 951
ARG A 325
GLU A 387
 None
 1.01A 4zzcE-3psiA:
undetectable		 4zzcE-3psiA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 926
SER A 932
PHE A 996
PHE A1105
TYR A 394
 None
 1.47A 5ef8A-3psiA:
undetectable		 5ef8A-3psiA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 943
VAL A 899
GLY A 815
THR A 754
LEU A 880
 None
 1.35A 5esgA-3psiA:
undetectable		 5esgA-3psiA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 795
ILE A 765
LEU A 799
LEU A 751
PHE A 823
 None
 1.07A 5im2A-3psiA:
undetectable		 5im2A-3psiA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 GLU A 387
PRO A 389
GLY A 953
ARG A 325
 None
 0.91A 5jcnB-3psiA:
undetectable		 5jcnB-3psiA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 758
THR A 820
ASN A 817
 None
 0.62A 5odiG-3psiA:
4.0		 5odiG-3psiA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 966
SER A 965
PHE A 962
ASP A 961
 None
 0.91A 5om3A-3psiA:
undetectable
5om3B-3psiA:
undetectable		 5om3A-3psiA:
5.45
5om3B-3psiA:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1060
VAL A1032
LEU A1102
ILE A1097
 None
 0.84A 5v0vA-3psiA:
2.1		 5v0vA-3psiA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 953
SER A 952
LEU A 948
PHE A 962
LEU A 966
 None
 1.17A 5w7pA-3psiA:
undetectable		 5w7pA-3psiA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 925
TYR A 950
GLU A 387
 None
 0.71A 5zmqD-3psiA:
undetectable
5zmqE-3psiA:
undetectable		 5zmqD-3psiA:
8.31
5zmqE-3psiA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 GLU A1038
ASP A1040
PRO A1041
 None
 0.58A 6berA-3psiA:
undetectable		 6berA-3psiA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 928
ASN A 929
ASN A 992
GLU A 387
 None
 1.20A 6h7uA-3psiA:
undetectable		 6h7uA-3psiA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 THR A1096
GLU A1076
ASN A1092
 None
 0.66A 6nj9K-3psiA:
undetectable		 6nj9K-3psiA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 325
PHE A 390
PHE A 954
 None
 0.92A 6nknC-3psiA:
undetectable
6nknJ-3psiA:
undetectable		 6nknC-3psiA:
11.99
6nknJ-3psiA:
3.89