SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 3pss QNR
(Aeromonas
hydrophila) 		4 / 6 LEU A  84
ASP A  62
LEU A 133
HIS A 117
 None
 1.09A 1errB-3pssA:
undetectable		 1errB-3pssA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3pss QNR
(Aeromonas
hydrophila) 		5 / 11 PHE A  47
LEU A  63
PHE A  32
SER A  33
PHE A  42
 None
 1.39A 3a9eB-3pssA:
undetectable		 3a9eB-3pssA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3pss QNR
(Aeromonas
hydrophila) 		3 / 3 PHE A  27
ASP A  49
ARG A  26
 None
 0.76A 4eahF-3pssA:
undetectable		 4eahF-3pssA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3pss QNR
(Aeromonas
hydrophila) 		3 / 3 PHE A  27
ASP A  49
ARG A  26
 None
 0.75A 4eahG-3pssA:
undetectable		 4eahG-3pssA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3pss QNR
(Aeromonas
hydrophila) 		4 / 7 PHE A  22
PHE A  42
PHE A   7
LEU A  37
 None
None
MLY  A   5 ( 4.4A)
None
 1.04A 4ejgA-3pssA:
undetectable		 4ejgA-3pssA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 3pss QNR
(Aeromonas
hydrophila) 		4 / 7 PHE A  42
PHE A  68
PHE A  27
LEU A  63
 None
 1.00A 4ejgA-3pssA:
undetectable		 4ejgA-3pssA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 3pss QNR
(Aeromonas
hydrophila) 		5 / 12 VAL A 191
VAL A 171
ALA A 154
LEU A 193
LEU A 158
 None
 1.19A 4i1rA-3pssA:
undetectable		 4i1rA-3pssA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 3pss QNR
(Aeromonas
hydrophila) 		5 / 12 LEU A  58
SER A  81
ALA A 101
LEU A  86
PHE A  68
 None
 1.46A 4qdcA-3pssA:
undetectable		 4qdcA-3pssA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 3pss QNR
(Aeromonas
hydrophila) 		4 / 6 ARG A  11
PHE A  32
CYH A  83
PHE A  98
 None
 1.49A 5mwyA-3pssA:
undetectable		 5mwyA-3pssA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 3pss QNR
(Aeromonas
hydrophila) 		4 / 6 CYH A  91
PHE A 123
LEU A  86
SER A  81
 None
 1.49A 6a7pB-3pssA:
undetectable		 6a7pB-3pssA:
16.33