SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pt8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3pt8 HEMOGLOBIN III
(Phacoides
pectinatus) 		4 / 6 VAL B  78
MET B  74
VAL B 125
ILE B 137
 None
 0.97A 1e06A-3pt8B:
undetectable		 1e06A-3pt8B:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3pt8 HEMOGLOBIN III
(Phacoides
pectinatus) 		5 / 12 LEU B 119
VAL B  78
MET B  74
LEU B  12
THR B 129
 None
 1.42A 2q7kA-3pt8B:
undetectable		 2q7kA-3pt8B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3pt8 HEMOGLOBIN III
(Phacoides
pectinatus) 		5 / 12 PHE B  30
TYR B  31
GLN B  66
LEU B 115
ILE B 140
 None
CYN  B 501 (-4.5A)
HEM  B 500 ( 3.7A)
None
None
 0.96A 4g1bA-3pt8B:
15.2		 4g1bA-3pt8B:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3pt8 HEMOGLOBIN III
(Phacoides
pectinatus) 		4 / 8 GLY B 127
LEU B 116
LEU B 119
GLU B 120
 None
 0.64A 4mwzB-3pt8B:
undetectable		 4mwzB-3pt8B:
17.67