SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DYR_A_TOPA407_1 (DIHYDROFOLATE REDUCTASE)	3pu6	UNCHARACTERIZED PROTEIN (Wolinella succinogenes)	5 / 11	ILE A 106 ALA A 60 LEU A 22 ILE A 71 PHE A 73	None	1.06A	1dyrA-3pu6A: undetectable	1dyrA-3pu6A: 24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	3pu6	UNCHARACTERIZED PROTEIN (Wolinella succinogenes)	3 / 3	ASP A 40 TYR A 39 GLU A 45	None	0.75A	1vm1A-3pu6A: undetectable	1vm1A-3pu6A: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_I_ACTI503_0 (RNA-DEPENDENT RNA POLYMERASE)	3pu6	UNCHARACTERIZED PROTEIN (Wolinella succinogenes)	4 / 5	LYS A 48 LEU A 49 GLU A 45 LEU A 6	None	1.22A	4k4yI-3pu6A: undetectable	4k4yI-3pu6A: 17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_1 (RNA-DIRECTED RNA POLYMERASE L)	3pu6	UNCHARACTERIZED PROTEIN (Wolinella succinogenes)	3 / 3	SER A 131 ASP A 40 ASP A 15	None	0.81A	4uckA-3pu6A: undetectable	4uckA-3pu6A: 18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JH7_B_6K9B503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	3pu6	UNCHARACTERIZED PROTEIN (Wolinella succinogenes)	4 / 7	LEU A 6 VAL A 35 GLU A 27 ILE A 110	None	0.71A	5jh7C-3pu6A: 4.2	5jh7C-3pu6A: 15.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DYR_A_TOPA407_1","DIHYDROFOLATE REDUCTASE","3pu6","UNCHARACTERIZED PROTEIN","Wolinella succinogenes",5,"ILE A 106;ALA A  60;LEU A  22;ILE A  71;PHE A  73","None","1.06A","1dyrA-3pu6A:undetectable","1dyrA-3pu6A:24.76"],["1VM1_A_TAZA504_1","BETA-LACTAMASE SHV-1","3pu6","UNCHARACTERIZED PROTEIN","Wolinella succinogenes",3,"ASP A  40;TYR A  39;GLU A  45","None","0.75A","1vm1A-3pu6A:undetectable","1vm1A-3pu6A:23.81"],["4K4Y_I_ACTI503_0","RNA-DEPENDENT RNA POLYMERASE","3pu6","UNCHARACTERIZED PROTEIN","Wolinella succinogenes",4,"LYS A  48;LEU A  49;GLU A  45;LEU A   6","None","1.22A","4k4yI-3pu6A:undetectable","4k4yI-3pu6A:17.76"],["4UCK_A_SAMA2409_1","RNA-DIRECTED RNA POLYMERASE L","3pu6","UNCHARACTERIZED PROTEIN","Wolinella succinogenes",3,"SER A 131;ASP A  40;ASP A  15","None","0.81A","4uckA-3pu6A:undetectable","4uckA-3pu6A:18.27"],["5JH7_B_6K9B503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","3pu6","UNCHARACTERIZED PROTEIN","Wolinella succinogenes",4,"LEU A   6;VAL A  35;GLU A  27;ILE A 110","None","0.71A","5jh7C-3pu6A:4.2","5jh7C-3pu6A:15.10"]]