SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.89A 1os6A-3puaA:
undetectable		 1os6A-3puaA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 VAL A 153
ARG A 157
VAL A 192
LEU A 174
 None
 0.80A 1pthA-3puaA:
undetectable		 1pthA-3puaA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 VAL A 153
ARG A 157
VAL A 192
LEU A 174
 None
 0.81A 1pthB-3puaA:
undetectable		 1pthB-3puaA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 12 THR A 325
TYR A 259
PHE A 268
SER A 244
ALA A 333
 None
OGA  A 454 (-4.6A)
None
None
EDO  A   9 ( 3.9A)
 1.29A 1q23A-3puaA:
undetectable
1q23B-3puaA:
undetectable		 1q23A-3puaA:
18.25
1q23B-3puaA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 10 TYR A 221
HIS A 376
ALA A 369
MET A 346
GLN A 345
 None
 1.31A 1uhoA-3puaA:
undetectable		 1uhoA-3puaA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 PHE A 366
PHE A 406
LEU A 377
MET A 346
 None
 1.18A 1wrlE-3puaA:
undetectable		 1wrlE-3puaA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		3 / 3 VAL A 178
ASP A 179
GLU A 150
 None
 0.59A 2qeuA-3puaA:
undetectable		 2qeuA-3puaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		3 / 3 VAL A 178
ASP A 179
GLU A 150
 None
 0.56A 2qeuC-3puaA:
undetectable		 2qeuC-3puaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 264
LEU A 190
ASP A 163
VAL A 164
THR A 165
 None
 0.59A 2wa2A-3puaA:
undetectable		 2wa2A-3puaA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 314
VAL A 105
LEU A 270
PRO A 126
 None
 0.81A 3bgdB-3puaA:
undetectable		 3bgdB-3puaA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 134
ASP A 210
ILE A 211
VAL A 129
 EDO  A   6 (-4.5A)
EDO  A   6 ( 4.8A)
None
None
 0.76A 3fi0G-3puaA:
undetectable		 3fi0G-3puaA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		6 / 10 LEU A 238
THR A 246
HIS A 249
ASP A 251
LYS A 266
ILE A 315
 OGA  A 454 ( 3.8A)
OGA  A 454 (-3.8A)
NI  A   2 ( 3.3A)
NI  A   2 ( 2.5A)
OGA  A 454 (-3.0A)
None
 0.90A 3kcxA-3puaA:
17.1		 3kcxA-3puaA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 10 LEU A 238
THR A 323
HIS A 249
ASP A 251
ILE A 315
 OGA  A 454 ( 3.8A)
OGA  A 454 (-2.9A)
NI  A   2 ( 3.3A)
NI  A   2 ( 2.5A)
None
 1.23A 3kcxA-3puaA:
17.1		 3kcxA-3puaA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.87A 3selX-3puaA:
undetectable		 3selX-3puaA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 6 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.92A 3sj1X-3puaA:
undetectable		 3sj1X-3puaA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 5 TRP A 217
GLY A 374
TRP A 371
PHE A 366
 None
 1.48A 3wqwA-3puaA:
undetectable		 3wqwA-3puaA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.93A 4hbfA-3puaA:
undetectable		 4hbfA-3puaA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.81A 4hc3A-3puaA:
undetectable		 4hc3A-3puaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 6 GLU A 282
GLU A 352
TYR A 349
GLU A 350
 None
 1.33A 4mi4A-3puaA:
undetectable		 4mi4A-3puaA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 5 THR A 246
ALA A 322
THR A 323
HIS A 249
 OGA  A 454 (-3.8A)
None
OGA  A 454 (-2.9A)
NI  A   2 ( 3.3A)
 1.22A 5ecmA-3puaA:
undetectable		 5ecmA-3puaA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 12 LEU A 395
GLY A 398
LYS A 400
GLU A 379
LEU A 378
 None
None
None
EDO  A   7 (-3.8A)
None
 1.18A 5nwvA-3puaA:
undetectable		 5nwvA-3puaA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 401
LEU A 402
MET A 373
LEU A 377
 None
 0.99A 5u4sA-3puaA:
undetectable		 5u4sA-3puaA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 401
LEU A 402
MET A 373
LEU A 377
 None
 0.95A 5u4sB-3puaA:
undetectable		 5u4sB-3puaA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 110
GLY A 134
ILE A 211
VAL A 129
ILE A 127
 None
EDO  A   6 (-4.5A)
None
None
None
 0.88A 6ectA-3puaA:
undetectable		 6ectA-3puaA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3pua PHD FINGER PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 110
GLY A 134
ILE A 211
VAL A 129
ILE A 127
 None
EDO  A   6 (-4.5A)
None
None
None
 0.86A 6ecxA-3puaA:
undetectable		 6ecxA-3puaA:
23.82