SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3puk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 6 ARG A 240
THR A 247
VAL A 248
LEU A 249
 None
 1.03A 2e1qA-3pukA:
undetectable		 2e1qA-3pukA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 6 ARG A 240
THR A 247
VAL A 248
LEU A 249
 None
 1.01A 2e1qC-3pukA:
undetectable		 2e1qC-3pukA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		3 / 3 LEU A 426
ARG A 425
ILE A 427
 None
 0.68A 2xn5B-3pukA:
undetectable		 2xn5B-3pukA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 6 LEU A  92
PHE A  91
ILE A 122
CYH A 114
 None
 0.88A 3ko0S-3pukA:
undetectable		 3ko0S-3pukA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 8 THR A 565
LEU A 150
GLN A 180
ALA A 176
 None
 1.01A 3kp6A-3pukA:
undetectable		 3kp6A-3pukA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 8 THR A 247
LEU A 573
LEU A 574
ILE A 577
 None
 0.94A 3nbqB-3pukA:
undetectable		 3nbqB-3pukA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		5 / 10 PHE A  23
LEU A  54
LEU A  45
THR A  42
THR A  41
 None
 1.01A 4e3hA-3pukA:
undetectable		 4e3hA-3pukA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		5 / 12 TYR A 160
GLY A 538
SER A 443
GLY A 446
THR A 247
 None
 1.14A 4mm8A-3pukA:
undetectable		 4mm8A-3pukA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		5 / 12 ILE A 238
ILE A 181
LEU A 235
PRO A 192
ILE A 237
 None
 1.06A 4p3qA-3pukA:
undetectable		 4p3qA-3pukA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 7 VAL A 147
ILE A 534
HIS A 566
LEU A 568
 None
 1.13A 4xo7B-3pukA:
undetectable		 4xo7B-3pukA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 5 ASN A 528
LEU A 188
THR A 231
CYH A 185
 None
 1.37A 5eu8A-3pukA:
undetectable		 5eu8A-3pukA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 8 LEU A  45
ILE A  18
PRO A 142
LEU A  44
 None
 0.95A 5g48A-3pukA:
undetectable		 5g48A-3pukA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 7 PHE A  23
LEU A  45
THR A  42
THR A  41
 None
 0.62A 5m78A-3pukA:
undetectable		 5m78A-3pukA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 5 PRO A 452
GLY A 417
THR A 418
ASN A 416
 None
 1.18A 5x23A-3pukA:
undetectable		 5x23A-3pukA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		5 / 11 ALA A 176
SER A 139
VAL A  88
ILE A  81
THR A  41
 None
 1.31A 5y80A-3pukA:
undetectable		 5y80A-3pukA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 7 ILE A 567
GLN A 143
VAL A 147
ALA A 548
 None
 0.78A 6cduC-3pukA:
undetectable
6cduD-3pukA:
undetectable		 6cduC-3pukA:
19.77
6cduD-3pukA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 8 ILE A 567
GLN A 143
VAL A 147
ALA A 548
 None
 0.79A 6cduD-3pukA:
undetectable
6cduE-3pukA:
undetectable		 6cduD-3pukA:
19.77
6cduE-3pukA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3puk SYNTAXIN-BINDING
PROTEIN 3
(Mus
musculus) 		4 / 7 ALA A 548
ILE A 567
GLN A 143
VAL A 147
 None
 0.82A 6cduF-3pukA:
undetectable
6cduJ-3pukA:
undetectable		 6cduF-3pukA:
19.77
6cduJ-3pukA:
19.77