SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3puo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		6 / 12 ILE A 203
ALA A   8
ALA A 207
PRO A 211
THR A  36
LEU A 261
 None
 1.46A 1cbsA-3puoA:
undetectable		 1cbsA-3puoA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 183
LEU A 182
GLY A 159
ILE A 157
SER A 152
 None
 1.03A 3bjwF-3puoA:
undetectable		 3bjwF-3puoA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 11 SER A  48
THR A  44
ALA A  79
GLY A  78
THR A  77
 None
 1.32A 3mg0H-3puoA:
undetectable
3mg0I-3puoA:
undetectable		 3mg0H-3puoA:
23.15
3mg0I-3puoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 201
GLY A 159
ILE A 160
VAL A  40
ILE A 131
 None
 0.98A 3n3iA-3puoA:
undetectable		 3n3iA-3puoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  74
GLY A  43
THR A  11
VAL A  60
VAL A  59
 None
 1.04A 3rukB-3puoA:
undetectable		 3rukB-3puoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  74
GLY A  43
THR A  11
VAL A  60
VAL A  59
 None
 1.10A 4nkvA-3puoA:
undetectable		 4nkvA-3puoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  74
GLY A  43
THR A  11
VAL A  60
VAL A  59
 None
 1.10A 4nkvC-3puoA:
undetectable		 4nkvC-3puoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  74
GLY A  43
THR A  11
VAL A  60
VAL A  59
 None
 1.12A 4nkvD-3puoA:
undetectable		 4nkvD-3puoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  24
LEU A  27
VAL A  28
ILE A  39
 None
 0.94A 4oj4A-3puoA:
undetectable		 4oj4A-3puoA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  59
ARG A 267
VAL A  10
PHE A  13
 None
 1.46A 5addA-3puoA:
undetectable
5addB-3puoA:
undetectable		 5addA-3puoA:
21.53
5addB-3puoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3puo DIHYDRODIPICOLINATE
SYNTHASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  97
ASP A  98
ILE A  74
GLY A  76
ILE A 128
 None
 1.03A 5kr1A-3puoA:
undetectable		 5kr1A-3puoA:
15.60