SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3put'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U70_A_MTXA187_1 (DIHYDROFOLATE REDUCTASE)	3put	HYPOTHETICAL CONSERVED PROTEIN (Rhizobium etli)	5 / 12	ALA A 75 GLU A 59 PHE A 38 ASN A 145 LEU A 143	None HEZ A 167 ( 4.3A) HEZ A 167 ( 4.2A) None HEZ A 167 (-4.5A)	1.35A	1u70A-3putA: undetectable	1u70A-3putA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB500_0 (ILEAL BILE ACID-BINDING PROTEIN)	3put	HYPOTHETICAL CONSERVED PROTEIN (Rhizobium etli)	4 / 7	THR A 105 VAL A 118 THR A 120 VAL A 12	None	0.24A	3em0B-3putA: 3.2	3em0B-3putA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM6_A_29EA603_1 (TRANSPORTER)	3put	HYPOTHETICAL CONSERVED PROTEIN (Rhizobium etli)	5 / 12	ALA A 89 TYR A 88 TYR A 90 PHE A 11 SER A 100	None HEZ A 167 (-4.5A) None None None	1.26A	4mm6A-3putA: undetectable	4mm6A-3putA: 14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2O_A_8N6A501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3put	HYPOTHETICAL CONSERVED PROTEIN (Rhizobium etli)	5 / 12	PHE A 25 LEU A 143 PHE A 108 MET A 117 TYR A 77	None HEZ A 167 (-4.5A) None None None	1.19A	5y2oA-3putA: undetectable	5y2oA-3putA: 22.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1U70_A_MTXA187_1","DIHYDROFOLATE REDUCTASE","3put","HYPOTHETICAL CONSERVED PROTEIN","Rhizobium etli",5,"ALA A  75;GLU A  59;PHE A  38;ASN A 145;LEU A 143","None;HEZ A 167 ( 4.3A);HEZ A 167 ( 4.2A);None;HEZ A 167 (-4.5A)","1.35A","1u70A-3putA:undetectable","1u70A-3putA:21.43"],["3EM0_B_CHDB500_0","ILEAL BILE ACID-BINDING PROTEIN","3put","HYPOTHETICAL CONSERVED PROTEIN","Rhizobium etli",4,"THR A 105;VAL A 118;THR A 120;VAL A  12","None","0.24A","3em0B-3putA:3.2","3em0B-3putA:20.86"],["4MM6_A_29EA603_1","TRANSPORTER","3put","HYPOTHETICAL CONSERVED PROTEIN","Rhizobium etli",5,"ALA A  89;TYR A  88;TYR A  90;PHE A  11;SER A 100","None;HEZ A 167 (-4.5A);None;None;None","1.26A","4mm6A-3putA:undetectable","4mm6A-3putA:14.84"],["5Y2O_A_8N6A501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3put","HYPOTHETICAL CONSERVED PROTEIN","Rhizobium etli",5,"PHE A  25;LEU A 143;PHE A 108;MET A 117;TYR A  77","None;HEZ A 167 (-4.5A);None;None;None","1.19A","5y2oA-3putA:undetectable","5y2oA-3putA:22.64"]]