SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.88A 1muiA-3pv2A:
undetectable		 1muiA-3pv2A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.92A 1rl8A-3pv2A:
undetectable		 1rl8A-3pv2A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 5 VAL A  85
ASN A  82
VAL A  23
ILE A  66
 None
 1.02A 1z2bC-3pv2A:
undetectable		 1z2bC-3pv2A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.83A 2ienA-3pv2A:
undetectable		 2ienA-3pv2A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A 225
GLY A 191
ASN A 189
VAL A  70
MET A  17
 None
 1.29A 2nyrB-3pv2A:
undetectable		 2nyrB-3pv2A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A  20
GLY A  67
GLY A  69
ASN A 192
PRO A 190
 None
 1.17A 2okcB-3pv2A:
undetectable		 2okcB-3pv2A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.84A 2pxcA-3pv2A:
undetectable		 2pxcA-3pv2A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 9 THR A 184
PHE A 181
VAL A 142
GLY A 206
ILE A 205
 None
 1.35A 2w98A-3pv2A:
undetectable		 2w98A-3pv2A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 7 VAL A  70
GLY A 131
VAL A 198
ASP A 132
 None
 0.91A 2y05A-3pv2A:
undetectable
2y05B-3pv2A:
undetectable		 2y05A-3pv2A:
22.93
2y05B-3pv2A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 LEU A 197
GLY A 195
VAL A  70
ILE A 182
ALA A 224
 None
 0.91A 2yy8A-3pv2A:
undetectable
2yy8B-3pv2A:
undetectable		 2yy8A-3pv2A:
18.02
2yy8B-3pv2A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.87A 3bvbA-3pv2A:
undetectable		 3bvbA-3pv2A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 ALA A 283
HIS A 344
LEU A 334
SER A 335
ARG A 327
 None
 1.32A 3bxoB-3pv2A:
undetectable		 3bxoB-3pv2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.88A 3ekpD-3pv2A:
undetectable		 3ekpD-3pv2A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.85A 3ektC-3pv2A:
undetectable		 3ektC-3pv2A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 3embA-3pv2A:
undetectable		 3embA-3pv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 ALA A 305
ILE A 302
ILE A 323
LEU A 288
ILE A 250
 None
 1.09A 3hbbA-3pv2A:
undetectable		 3hbbA-3pv2A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 4 GLY A 291
VAL A 274
GLY A 271
THR A 303
 None
 0.92A 3ib2A-3pv2A:
undetectable		 3ib2A-3pv2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.84A 3jw2A-3pv2A:
undetectable		 3jw2A-3pv2A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.84A 3lzuB-3pv2A:
undetectable		 3lzuB-3pv2A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 194
GLY A  67
VAL A  21
ALA A 196
SER A  65
 None
 1.03A 3p2kD-3pv2A:
undetectable		 3p2kD-3pv2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 3p97A-3pv2A:
undetectable		 3p97A-3pv2A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.84A 3tl9B-3pv2A:
undetectable		 3tl9B-3pv2A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 194
GLY A  67
VAL A  23
ALA A 210
ASP A 114
 None
 0.97A 4a6dA-3pv2A:
undetectable		 4a6dA-3pv2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 194
GLY A  67
VAL A  23
ALA A 210
ASP A 114
 None
 1.00A 4a6eA-3pv2A:
undetectable		 4a6eA-3pv2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.79A 4ctjA-3pv2A:
undetectable		 4ctjA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.92A 4ctjC-3pv2A:
undetectable		 4ctjC-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 4ctkA-3pv2A:
undetectable		 4ctkA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4eilA-3pv2A:
undetectable		 4eilA-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4eilB-3pv2A:
undetectable		 4eilB-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4eilC-3pv2A:
undetectable		 4eilC-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.37A 4eilE-3pv2A:
undetectable		 4eilE-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 5 LEU A 118
LEU A 106
ILE A  86
ARG A  87
 None
 0.97A 4klrA-3pv2A:
undetectable		 4klrA-3pv2A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.37A 4kyaA-3pv2A:
undetectable		 4kyaA-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.47A 4kyaB-3pv2A:
undetectable		 4kyaB-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4kyaC-3pv2A:
undetectable		 4kyaC-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.44A 4kyaD-3pv2A:
undetectable		 4kyaD-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4kyaE-3pv2A:
undetectable		 4kyaE-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.45A 4kyaF-3pv2A:
undetectable		 4kyaF-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.38A 4kyaG-3pv2A:
undetectable		 4kyaG-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 VAL A 142
ALA A 144
SER A 133
LEU A 168
VAL A 165
 None
 1.46A 4kyaH-3pv2A:
undetectable		 4kyaH-3pv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.83A 4ll3B-3pv2A:
undetectable		 4ll3B-3pv2A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.84A 4ll3A-3pv2A:
undetectable		 4ll3A-3pv2A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 10 ASP A 134
THR A 306
GLN A 307
THR A 310
ASP A 232
 None
 1.31A 4n9uA-3pv2A:
undetectable		 4n9uA-3pv2A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 LEU A 115
THR A 209
ILE A 227
LYS A 180
ILE A 207
 None
 1.11A 4o2bB-3pv2A:
undetectable		 4o2bB-3pv2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 7 LEU A 412
ALA A 416
LEU A 355
ALA A 401
 None
 0.64A 4z90F-3pv2A:
undetectable
4z90G-3pv2A:
undetectable
4z90H-3pv2A:
undetectable
4z90J-3pv2A:
undetectable		 4z90F-3pv2A:
22.08
4z90G-3pv2A:
22.08
4z90H-3pv2A:
22.08
4z90J-3pv2A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 11 ALA A 224
LEU A 197
LEU A 204
ILE A  20
GLY A 146
 None
 1.22A 5dxbB-3pv2A:
undetectable		 5dxbB-3pv2A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 4 LEU A  91
ILE A  92
GLY A  27
ILE A  86
 None
 0.88A 5dzk3-3pv2A:
undetectable
5dzkm-3pv2A:
undetectable		 5dzk3-3pv2A:
0.61
5dzkm-3pv2A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.76A 5e9qA-3pv2A:
undetectable		 5e9qA-3pv2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.72A 5ec8A-3pv2A:
undetectable		 5ec8A-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.89A 5ec8C-3pv2A:
undetectable		 5ec8C-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.75A 5ehgA-3pv2A:
undetectable		 5ehgA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.89A 5ehgC-3pv2A:
undetectable		 5ehgC-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.77A 5ehiA-3pv2A:
undetectable		 5ehiA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.79A 5eifA-3pv2A:
undetectable		 5eifA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.74A 5eiwA-3pv2A:
undetectable		 5eiwA-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.76A 5ekxA-3pv2A:
undetectable		 5ekxA-3pv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.81A 5ekxB-3pv2A:
undetectable		 5ekxB-3pv2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 8 ILE A  86
ASP A  83
ARG A  87
LEU A  29
 None
 1.03A 5hwaA-3pv2A:
undetectable		 5hwaA-3pv2A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.87A 5ikmA-3pv2A:
undetectable		 5ikmA-3pv2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.86A 5kqrA-3pv2A:
undetectable		 5kqrA-3pv2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.84A 5kqsA-3pv2A:
undetectable		 5kqsA-3pv2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.92A 5m5bA-3pv2A:
undetectable		 5m5bA-3pv2A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 4 GLN A 307
THR A 306
THR A 113
LEU A 314
 None
 1.49A 5m66B-3pv2A:
undetectable		 5m66B-3pv2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 LEU A 115
THR A 209
ILE A 227
LYS A 180
ILE A 207
 None
 1.09A 5mioB-3pv2A:
undetectable		 5mioB-3pv2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 5njvA-3pv2A:
undetectable		 5njvA-3pv2A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.84A 5njvB-3pv2A:
undetectable		 5njvB-3pv2A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 5njvC-3pv2A:
undetectable		 5njvC-3pv2A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.97A 5njvD-3pv2A:
undetectable		 5njvD-3pv2A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 287
ALA A 286
VAL A 321
GLY A 249
ILE A 323
 None
 0.87A 5t2zB-3pv2A:
undetectable		 5t2zB-3pv2A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.83A 5vimA-3pv2A:
undetectable		 5vimA-3pv2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.82A 5vimB-3pv2A:
undetectable		 5vimB-3pv2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WP1_A_BEZA403_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3pv2 DEGQ
(Legionella
fallonii) 		4 / 4 GLY A 150
PHE A 149
ASN A  22
LYS A 157
 None
 0.96A 5wp1A-3pv2A:
0.2		 5wp1A-3pv2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.87A 5wz1B-3pv2A:
undetectable		 5wz1B-3pv2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.81A 5wz2A-3pv2A:
undetectable		 5wz2A-3pv2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 5wz2B-3pv2A:
undetectable		 5wz2B-3pv2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3pv2 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.79A 5wz2C-3pv2A:
undetectable		 5wz2C-3pv2A:
21.71