SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 8 SER A 193
ILE A 207
GLY A 206
GLY A 222
 None
 0.76A 1me7A-3pv4A:
undetectable		 1me7A-3pv4A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 5 VAL A  85
ASN A  82
VAL A  23
ILE A  66
 None
 0.98A 1z2bC-3pv4A:
undetectable		 1z2bC-3pv4A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ASN A 208
ALA A 196
LEU A  13
MET A   9
THR A 184
 None
 1.37A 2aa6A-3pv4A:
undetectable		 2aa6A-3pv4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ASN A 208
ALA A 196
LEU A  13
MET A   9
THR A 184
 None
 1.38A 2aa6B-3pv4A:
undetectable		 2aa6B-3pv4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 3pv4 DEGQ
(Legionella
fallonii) 		6 / 12 LEU A 334
ILE A 297
ILE A 312
GLY A 246
VAL A 325
ILE A 323
 None
 1.35A 2hs1B-3pv4A:
undetectable		 2hs1B-3pv4A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.83A 2pxcA-3pv4A:
undetectable		 2pxcA-3pv4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 11 SER A 281
MET A 248
VAL A 252
GLY A 287
VAL A 308
 None
 1.29A 2uxpB-3pv4A:
undetectable		 2uxpB-3pv4A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 1.00A 2wa2B-3pv4A:
undetectable		 2wa2B-3pv4A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 7 VAL A  70
GLY A 131
VAL A 198
ASP A 132
 None
 0.93A 2y05A-3pv4A:
undetectable
2y05B-3pv4A:
undetectable		 2y05A-3pv4A:
21.47
2y05B-3pv4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ALA A 224
LEU A 197
LEU A 204
ILE A  20
GLY A 146
 None
 1.20A 2yjaB-3pv4A:
undetectable		 2yjaB-3pv4A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 11 LEU A 197
GLY A 195
VAL A  70
ILE A 182
ALA A 224
 None
 0.92A 2yy8A-3pv4A:
undetectable
2yy8B-3pv4A:
undetectable		 2yy8A-3pv4A:
18.73
2yy8B-3pv4A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 HIS A  84
GLY A 194
SER A 193
ILE A  72
LEU A 115
 None
 0.98A 3cjtO-3pv4A:
undetectable		 3cjtO-3pv4A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 6 LEU A  96
LYS A 126
ALA A  19
PRO A  74
 None
 1.21A 3gv1A-3pv4A:
undetectable
3gv1C-3pv4A:
undetectable		 3gv1A-3pv4A:
16.67
3gv1C-3pv4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 6 LEU A  96
LYS A 126
ALA A  19
PRO A  74
 None
 1.21A 3gv1A-3pv4A:
undetectable
3gv1B-3pv4A:
undetectable		 3gv1A-3pv4A:
16.67
3gv1B-3pv4A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 4 GLY A 291
VAL A 274
GLY A 271
THR A 303
 None
 0.87A 3ib2A-3pv4A:
undetectable		 3ib2A-3pv4A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 9 ILE A 227
ILE A 205
VAL A 230
ILE A 182
ILE A 225
 None
 1.25A 3p4wB-3pv4A:
undetectable		 3p4wB-3pv4A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 3p97A-3pv4A:
undetectable		 3p97A-3pv4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 5 SER A 193
ILE A  20
GLY A  67
PRO A 148
 None
 1.04A 3uboB-3pv4A:
undetectable		 3uboB-3pv4A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.80A 4ctjA-3pv4A:
undetectable		 4ctjA-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.92A 4ctjC-3pv4A:
undetectable		 4ctjC-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.79A 4ctkA-3pv4A:
undetectable		 4ctkA-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 11 ILE A 312
ILE A 297
ALA A 336
ALA A 286
ILE A 250
 None
 1.20A 4h1nA-3pv4A:
undetectable		 4h1nA-3pv4A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 5 LEU A 118
LEU A 106
ILE A  86
ARG A  87
 None
 0.83A 4klrA-3pv4A:
undetectable		 4klrA-3pv4A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3pv4 DEGQ
(Legionella
fallonii) 		6 / 12 LEU A 334
ILE A 297
ILE A 312
GLY A 246
VAL A 325
ILE A 323
 None
 1.40A 4q1xB-3pv4A:
undetectable		 4q1xB-3pv4A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		6 / 12 THR A 209
ALA A 224
LEU A 197
LEU A 204
ILE A  20
GLY A 146
 None
 1.36A 4xi3B-3pv4A:
undetectable		 4xi3B-3pv4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 7 ILE A 205
LEU A 197
GLY A 202
LYS A 201
 None
 1.01A 4z69A-3pv4A:
undetectable		 4z69A-3pv4A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 11 ALA A 224
LEU A 197
LEU A 204
ILE A  20
GLY A 146
 None
 1.19A 5dxbB-3pv4A:
undetectable		 5dxbB-3pv4A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 5e9qA-3pv4A:
undetectable		 5e9qA-3pv4A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.73A 5ec8A-3pv4A:
undetectable		 5ec8A-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.88A 5ec8C-3pv4A:
undetectable		 5ec8C-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.76A 5ehgA-3pv4A:
undetectable		 5ehgA-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.89A 5ehgC-3pv4A:
undetectable		 5ehgC-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.81A 5eifA-3pv4A:
undetectable		 5eifA-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.83A 5ekxB-3pv4A:
undetectable		 5ekxB-3pv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 5ikmA-3pv4A:
undetectable		 5ikmA-3pv4A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.87A 5kqrA-3pv4A:
undetectable		 5kqrA-3pv4A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.84A 5kqsA-3pv4A:
undetectable		 5kqsA-3pv4A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.93A 5m5bA-3pv4A:
undetectable		 5m5bA-3pv4A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.86A 5njvA-3pv4A:
undetectable		 5njvA-3pv4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 5njvB-3pv4A:
undetectable		 5njvB-3pv4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.80A 5njvC-3pv4A:
undetectable		 5njvC-3pv4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.97A 5njvD-3pv4A:
undetectable		 5njvD-3pv4A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A  86
LEU A 118
SER A 193
VAL A  85
GLY A 194
 None
 1.18A 5nnaA-3pv4A:
undetectable		 5nnaA-3pv4A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A  86
LEU A 118
SER A 193
VAL A  85
GLY A 194
 None
 1.21A 5nnaB-3pv4A:
undetectable		 5nnaB-3pv4A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A  86
LEU A 118
SER A 193
VAL A  85
GLY A 194
 None
 1.21A 5nnaC-3pv4A:
undetectable		 5nnaC-3pv4A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 ILE A  86
LEU A 118
SER A 193
VAL A  85
GLY A 194
 None
 1.15A 5nnaD-3pv4A:
undetectable		 5nnaD-3pv4A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.85A 5vimA-3pv4A:
undetectable		 5vimA-3pv4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.82A 5vimB-3pv4A:
undetectable		 5vimB-3pv4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3pv4 DEGQ
(Legionella
fallonii) 		4 / 8 ILE A 237
GLN A 276
VAL A 230
ASP A  83
 None
 1.06A 5vlmF-3pv4A:
undetectable		 5vlmF-3pv4A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.87A 5wz1B-3pv4A:
undetectable		 5wz1B-3pv4A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.80A 5wz2A-3pv4A:
undetectable		 5wz2A-3pv4A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.78A 5wz2B-3pv4A:
undetectable		 5wz2B-3pv4A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 GLY A 206
GLY A  69
GLY A 194
VAL A  94
ILE A  79
 None
 0.79A 5wz2C-3pv4A:
undetectable		 5wz2C-3pv4A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pv4 DEGQ
(Legionella
fallonii) 		5 / 12 VAL A 274
ASP A 232
SER A 133
VAL A 277
ASN A 278
 None
 1.35A 6h7lA-3pv4A:
undetectable		 6h7lA-3pv4A:
13.25