SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pvc'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J3J_A_CP6A609_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	ALA A 253 ASP A 166 ASN A 664 TYR A 594 THR A 252	None	1.09A	1j3jA-3pvcA: undetectable	1j3jA-3pvcA: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J3J_B_CP6B709_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 9	ALA A 253 ASP A 166 ASN A 664 TYR A 594 THR A 252	None	1.17A	1j3jB-3pvcA: undetectable	1j3jB-3pvcA: 15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JG4_A_SAMA500_1 (PROTEIN-L-ISOASPARTA TE O-METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	GLU A  64 GLY A  66 GLU A 101 ASP A 156	None	0.78A	1jg4A-3pvcA: 6.5	1jg4A-3pvcA: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_C_THAC3_1 (LIVER CARBOXYLESTERASE I)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	SER A  99 LEU A 150 LEU A 110 LEU A 127 LEU A 105	None	1.14A	1mx1C-3pvcA: undetectable	1mx1C-3pvcA: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.06A	1p6kB-3pvcA: undetectable	1p6kB-3pvcA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	1qzfA-3pvcA: undetectable	1qzfA-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	1qzfB-3pvcA: undetectable	1qzfB-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	1qzfC-3pvcA: undetectable	1qzfC-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	1qzfD-3pvcA: undetectable	1qzfD-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	1qzfE-3pvcA: 2.5	1qzfE-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.09A	1rs6B-3pvcA: undetectable	1rs6B-3pvcA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.07A	1rs7B-3pvcA: undetectable	1rs7B-3pvcA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SBR_B_VIBB504_1 (YKOF)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	HIS A 458 LEU A 463 ILE A 270 SER A 276	None None FAD  A 690 (-4.6A) None	1.14A	1sbrA-3pvcA: undetectable 1sbrB-3pvcA: undetectable	1sbrA-3pvcA: 14.71 1sbrB-3pvcA: 14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_A_CLMA1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.78A	1usqA-3pvcA: undetectable	1usqA-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_B_CLMB1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.78A	1usqB-3pvcA: undetectable	1usqB-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_C_CLMC1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.81A	1usqC-3pvcA: undetectable	1usqC-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_D_CLMD1142_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.77A	1usqD-3pvcA: undetectable	1usqD-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_E_CLME1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.76A	1usqE-3pvcA: undetectable	1usqE-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1USQ_F_CLMF1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.75A	1usqF-3pvcA: undetectable	1usqF-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_D_TFPD207_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	LEU A 142 PHE A 332 PHE A 325 LEU A 627	None None None FAD  A 690 (-4.3A)	1.00A	1wrlC-3pvcA: undetectable 1wrlD-3pvcA: undetectable	1wrlC-3pvcA: 9.00 1wrlD-3pvcA: 9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZQ_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.05A	1zzqB-3pvcA: undetectable	1zzqB-3pvcA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZU_A_ACTA860_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.06A	1zzuA-3pvcA: undetectable	1zzuA-3pvcA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZU_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.10A	1zzuB-3pvcA: undetectable	1zzuB-3pvcA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B25_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	3 / 3	GLY A  66 GLU A 101 ASP A 178	None	0.37A	2b25B-3pvcA: 10.0	2b25B-3pvcA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BLA_A_CP6A302_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 11	ALA A 253 ASP A 166 ASN A 664 TYR A 594 THR A 252	None	1.16A	2blaA-3pvcA: undetectable	2blaA-3pvcA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DDW_B_PXLB1005_1 (PYRIDOXINE KINASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	THR A  75 HIS A  39 GLY A  34 ASP A  33	None	0.90A	2ddwB-3pvcA: undetectable	2ddwB-3pvcA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_A_CLMA1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.74A	2jkjA-3pvcA: undetectable	2jkjA-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_B_CLMB1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.74A	2jkjB-3pvcA: undetectable	2jkjB-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_C_CLMC1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.75A	2jkjC-3pvcA: undetectable	2jkjC-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKJ_E_CLME1141_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.73A	2jkjE-3pvcA: undetectable	2jkjE-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_A_CLMA1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.78A	2jklA-3pvcA: undetectable	2jklA-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_B_CLMB1144_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.79A	2jklB-3pvcA: undetectable	2jklB-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_C_CLMC1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.82A	2jklC-3pvcA: undetectable	2jklC-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_D_CLMD1145_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.79A	2jklD-3pvcA: undetectable	2jklD-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_E_CLME1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.78A	2jklE-3pvcA: undetectable	2jklE-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JKL_F_CLMF1143_0 (DR HEMAGGLUTININ STRUCTURAL SUBUNIT)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PRO A 299 GLY A 273 ILE A 269 GLY A 271	None FAD  A 690 (-3.3A) None FAD  A 690 (-3.3A)	0.79A	2jklF-3pvcA: undetectable	2jklF-3pvcA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.16A	2oipC-3pvcA: 2.1	2oipC-3pvcA: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PXC_A_SAMA500_0 (GENOME POLYPROTEIN [CONTAINS: CAPSID PROTEIN C (CORE PROTEIN) ENVELOPE PROTEIN M (MATRIX PROTEIN) MAJOR ENVELOPE PROTEIN E NON-STRUCTURAL PROTEIN 1 (NS1) NON-STRUCTURAL PROTEIN 2A (NS2A) FLAVIVIRIN PROTEASE NS2B REGULATORY SUBUNIT FLAVIVIRIN PROTEASE NS3 CATALYTIC SUBUNIT NON-STRUCTURAL PROTEIN 4A (NS4A) NON-STRUCTURAL PROTEIN 4B (NS4B) RNA-DIRECTED RNA POLYMERASE (EC 2.7.7.48) (NS5)])	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.89A	2pxcA-3pvcA: 5.0	2pxcA-3pvcA: 16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QR2_B_VK3B235_1 (PROTEIN (QUINONE REDUCTASE TYPE 2))	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PHE A 326 PHE A 325 GLY A 626 GLY A 625	None None None FAD  A 690 ( 4.5A)	0.85A	2qr2A-3pvcA: undetectable 2qr2B-3pvcA: undetectable	2qr2A-3pvcA: 16.10 2qr2B-3pvcA: 16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QR2_B_VK3B236_1 (PROTEIN (QUINONE REDUCTASE TYPE 2))	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 626 GLY A 625 PHE A 326 PHE A 325	None FAD  A 690 ( 4.5A) None None	0.85A	2qr2A-3pvcA: undetectable 2qr2B-3pvcA: undetectable	2qr2A-3pvcA: 16.10 2qr2B-3pvcA: 16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RCT_A_RTLA140_1 (RETINOL-BINDING PROTEIN II, CELLULAR)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	3 / 3	GLN A 192 THR A  65 TRP A 189	None	1.10A	2rctA-3pvcA: undetectable	2rctA-3pvcA: 12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_0 (NON-STRUCTURAL PROTEIN 5)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	SER A 634 GLY A 631 GLY A 466 GLY A 625 LEU A 463	None FAD  A 690 (-3.0A) FAD  A 690 ( 3.7A) FAD  A 690 ( 4.5A) None	0.93A	2wa2B-3pvcA: 6.3	2wa2B-3pvcA: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_B_SAMB530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	ALA A 174 GLY A 205 THR A 243 GLY A 242 LEU A  95 PHE A  62	None	1.46A	2y7hB-3pvcA: 8.6	2y7hB-3pvcA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_C_SAMC530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	ALA A 174 GLY A 205 THR A 243 GLY A 242 LEU A  95 PHE A  62	None	1.46A	2y7hC-3pvcA: 8.3	2y7hC-3pvcA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_A_SAMA300_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 9	ALA A 280 GLY A 271 LEU A 281 ILE A 274 LEU A 418	None FAD  A 690 (-3.3A) None FAD  A 690 (-4.8A) None	0.98A	2z0yA-3pvcA: undetectable	2z0yA-3pvcA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM8_A_ACAA511_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	ALA A 464 ILE A 270 ILE A 462 HIS A 458	None FAD  A 690 (-4.6A) None None	0.95A	2zm8A-3pvcA: undetectable	2zm8A-3pvcA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMA_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	ALA A 464 ILE A 270 ILE A 462 HIS A 458	None FAD  A 690 (-4.6A) None None	0.97A	2zmaA-3pvcA: undetectable	2zmaA-3pvcA: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	TYR A 508 GLY A 273 ALA A 277 LEU A 278 PRO A 411	FAD  A 690 (-4.2A) FAD  A 690 (-3.3A) None None CL  A 691 (-4.6A)	1.00A	2zulA-3pvcA: 10.2	2zulA-3pvcA: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLB_D_TMQD614_1 (DHFR-TS)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.18A	3clbD-3pvcA: undetectable	3clbD-3pvcA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS8_A_BRLA503_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A 137 CYH A 138 ILE A  98 LEU A 168 HIS A  96	None	1.30A	3cs8A-3pvcA: undetectable	3cs8A-3pvcA: 17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DH0_A_SAMA220_1 (SAM DEPENDENT METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	ARG A 630 TYR A 312 ASP A 506 GLU A 541	None	1.40A	3dh0A-3pvcA: 11.1	3dh0A-3pvcA: 12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	TYR A 508 GLY A 273 ALA A 277 LEU A 278 PRO A 411	FAD  A 690 (-4.2A) FAD  A 690 (-3.3A) None None CL  A 691 (-4.6A)	1.00A	3dmhA-3pvcA: 9.9	3dmhA-3pvcA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FUU_A_ADNA0_1 (DIMETHYLADENOSINE TRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  68 GLU A 101 LYS A 102 ASP A 156	None	0.66A	3fuuA-3pvcA: 8.8	3fuuA-3pvcA: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCZ_A_SAMA4633_0 (POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	SER A 634 GLY A 631 GLY A 466 GLY A 625 LEU A 463	None FAD  A 690 (-3.0A) FAD  A 690 ( 3.7A) FAD  A 690 ( 4.5A) None	0.97A	3gczA-3pvcA: 5.2	3gczA-3pvcA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GRY_A_SAMA300_0 (DIMETHYLADENOSINE TRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLU A  64 GLY A  66 GLY A  68 GLU A 101 ASP A 156	None	0.57A	3gryA-3pvcA: 10.0	3gryA-3pvcA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HBB_D_TMQD614_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.19A	3hbbD-3pvcA: undetectable	3hbbD-3pvcA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.21A	3hj3C-3pvcA: undetectable	3hj3C-3pvcA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IHT_A_SAMA200_0 (S-ADENOSYL-L-METHION INE METHYL TRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  68 GLY A  70 ASP A 156 ASP A 178	None	0.38A	3ihtA-3pvcA: 11.2	3ihtA-3pvcA: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_A_PNNA5001_0 (TRANSCRIPTIONAL REGULATOR TCAR)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	THR A 657 LEU A 653 SER A 328 ASN A 316	None	1.13A	3kp2A-3pvcA: undetectable 3kp2B-3pvcA: undetectable	3kp2A-3pvcA: 11.74 3kp2B-3pvcA: 11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_1 (SAM-DEPENDENT METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 4	GLY A  66 GLU A 101 ASP A 156 ASP A 178	None	0.52A	3mb5A-3pvcA: 11.6	3mb5A-3pvcA: 15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P97_A_SAMA263_0 (NON-STRUCTURAL PROTEIN 5)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.96A	3p97A-3pvcA: 6.0	3p97A-3pvcA: 16.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PS9_A_SAMA670_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	7 / 12	GLU A  64 GLY A  66 ASN A  72 ASP A 156 GLY A 179 PHE A 180 MET A 188	None	0.77A	3ps9A-3pvcA: 58.8	3ps9A-3pvcA: 60.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PS9_A_SAMA670_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	7 / 12	GLU A  64 GLY A  66 ASN A  72 LYS A 102 ASP A 156 GLY A 179 MET A 188	None	0.49A	3ps9A-3pvcA: 58.8	3ps9A-3pvcA: 60.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PS9_A_SAMA670_1 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 6	GLY A  68 THR A  69 LEU A  71 GLU A 101 ASP A 178	None	0.47A	3ps9A-3pvcA: 58.8	3ps9A-3pvcA: 60.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QFX_A_CP6A602_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.16A	3qfxA-3pvcA: undetectable	3qfxA-3pvcA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QFX_B_CP6B702_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.16A	3qfxB-3pvcA: undetectable	3qfxB-3pvcA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QG2_A_CP6A609_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	ALA A 253 ASP A 166 ASN A 664 TYR A 594 THR A 252	None	1.10A	3qg2A-3pvcA: 2.2	3qg2A-3pvcA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QG2_B_CP6B709_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 11	ALA A 253 ASP A 166 ASN A 664 TYR A 594 THR A 252	None	1.10A	3qg2B-3pvcA: undetectable	3qg2B-3pvcA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROZ_A_NCAA266_0 (APOLIPOPROTEIN A-I-BINDING PROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	ASP A 654 LEU A 653 ALA A 136 THR A 324	None	1.12A	3rozA-3pvcA: 4.1	3rozA-3pvcA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S53_A_017A201_2 (PROTEASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 11	LEU A 292 ALA A 280 ILE A 462 ILE A 274 ILE A 269	None None None FAD  A 690 (-4.8A) None	1.03A	3s53B-3pvcA: undetectable	3s53B-3pvcA: 11.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SGL_A_SAMA692_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	12 / 12	GLU A  64 GLY A  66 GLY A  68 THR A  69 LEU A  71 ASN A  72 LYS A 102 TYR A 103 ASP A 156 VAL A 157 GLY A 179 PHE A 180	None	0.57A	3sglA-3pvcA: 68.8	3sglA-3pvcA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_C_SALC404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	ALA A 382 ARG A 385 ALA A 358 ARG A 364	None	1.10A	3twpC-3pvcA: undetectable	3twpC-3pvcA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UWL_B_FOZB316_0 (THYMIDYLATE SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	LEU A 435 ILE A 270 LEU A 292 GLY A 272 ILE A 269 ALA A 280	FAD  A 690 (-4.6A) FAD  A 690 (-4.6A) None FAD  A 690 (-3.6A) None None	1.48A	3uwlB-3pvcA: undetectable	3uwlB-3pvcA: 18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_A_SAMA501_0 (MNMC2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  68 ASN A  72 LYS A 102 PHE A 180	None	0.81A	3vywA-3pvcA: 20.0	3vywA-3pvcA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_C_SAMC401_1 (MNMC2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	GLY A  68 GLU A 101 ASP A 156 ASP A 178	None	0.41A	3vywC-3pvcA: 20.2	3vywC-3pvcA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_D_VIVD301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	SER A  59 LEU A  92 PHE A  80 ILE A  98 LEU A 168	None	1.22A	3w67D-3pvcA: undetectable	3w67D-3pvcA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOA_A_ACRA1587_2 (TREHALOSE SYNTHASE/AMYLASE TRES)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	3 / 3	ARG A  51 PHE A  48 PRO A  49	None	0.81A	3zoaB-3pvcA: undetectable	3zoaB-3pvcA: 22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTJ_A_SAMA1263_0 (NON-STRUCTURAL PROTEIN 5)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.86A	4ctjA-3pvcA: 4.8	4ctjA-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTK_A_SAMA1263_0 (POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.91A	4ctkA-3pvcA: 6.2	4ctkA-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D39_B_ACTB860_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.10A	4d39B-3pvcA: undetectable	4d39B-3pvcA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FE1_B_PQNB840_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 9	MET A 427 ARG A 286 ALA A 282 LEU A 283 ALA A 288	None	1.45A	4fe1B-3pvcA: undetectable	4fe1B-3pvcA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KCN_B_ACTB804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 4	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.09A	4kcnB-3pvcA: 0.7	4kcnB-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTT_A_SAMA405_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 8	ALA A 644 GLU A 649 ASP A 173 ASP A 151 ILE A  98	None	1.33A	4kttB-3pvcA: undetectable	4kttB-3pvcA: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTT_A_SAMA405_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 8	ALA A 644 GLU A 649 ILE A  61 ASP A 151 ILE A  98	None	1.48A	4kttB-3pvcA: undetectable	4kttB-3pvcA: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCU_B_SAMB603_0 (CYSTATHIONINE BETA-SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 9	ASP A 576 LEU A 637 PHE A 325 VAL A 581 ILE A 574	None	1.39A	4pcuA-3pvcA: 5.7 4pcuB-3pvcA: 5.5	4pcuA-3pvcA: 21.87 4pcuB-3pvcA: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	GLU A  64 THR A  65 THR A 201 ASN A  46	None	0.99A	4pfjA-3pvcA: 3.8	4pfjA-3pvcA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	GLU A  64 THR A  65 THR A 201 ASN A  46	None	1.04A	4pfjB-3pvcA: 2.9	4pfjB-3pvcA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_A_MTXA604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	4q0dA-3pvcA: undetectable	4q0dA-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_B_MTXB604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	4q0dB-3pvcA: undetectable	4q0dB-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0D_E_MTXE604_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.11A	4q0dE-3pvcA: undetectable	4q0dE-3pvcA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RKU_A_PQNA5001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	PHE A  67 ARG A 128 ALA A 124 LEU A 127	None	1.01A	4rkuA-3pvcA: undetectable 4rkuJ-3pvcA: undetectable	4rkuA-3pvcA: 22.19 4rkuJ-3pvcA: 5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_C_29SC601_1 (ESTROGEN RECEPTOR)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	LEU A 394 ALA A 392 LEU A 388 LEU A 503 LEU A 509 GLY A 407	None	1.26A	4xi3C-3pvcA: undetectable	4xi3C-3pvcA: 15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XK8_A_PQNA844_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	PHE A  67 ARG A 128 ALA A 124 LEU A 127	None	1.05A	4xk8A-3pvcA: undetectable	4xk8A-3pvcA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E9Q_A_SAMA301_0 (GENOME POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.87A	5e9qA-3pvcA: 6.2	5e9qA-3pvcA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E9Q_C_SAMC4000_0 (GENOME POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.95A	5e9qC-3pvcA: 5.9	5e9qC-3pvcA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EC8_C_SAMC4000_0 (GENOME POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.88A	5ec8C-3pvcA: 5.9	5ec8C-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EHG_A_SAMA301_0 (RNA-DIRECTED RNA POLYMERASE NS5)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.90A	5ehgA-3pvcA: 6.0	5ehgA-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIF_A_SAMA301_0 (GENOME POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.88A	5eifA-3pvcA: 6.2	5eifA-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EIW_C_SAMC4000_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.85A	5eiwC-3pvcA: 6.2	5eiwC-3pvcA: 15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EKX_A_SAMA301_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 LYS A 102 VAL A 157 ASP A 178	None	0.93A	5ekxA-3pvcA: 4.1	5ekxA-3pvcA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	GLY A  66 GLY A  68 GLU A 101 ASP A 156	None	0.72A	5ergB-3pvcA: 3.3	5ergB-3pvcA: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 7	GLY A  66 GLY A  68 GLU A 101 ASP A 178	None	0.60A	5ergB-3pvcA: 3.3	5ergB-3pvcA: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKM_A_SAMA311_0 (NS5 METHYL TRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.86A	5ikmA-3pvcA: 6.1	5ikmA-3pvcA: 17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQS_A_SAMA307_0 (GENOME POLYPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 12	GLY A  66 GLY A  70 ASP A 156 VAL A 157 ASP A 178	None	0.88A	5kqsA-3pvcA: 5.2	5kqsA-3pvcA: 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8R_B_PQNB841_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 9	MET A 427 ARG A 286 ALA A 282 LEU A 283 ALA A 288	None	1.49A	5l8rB-3pvcA: 0.1	5l8rB-3pvcA: 23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVS_B_ADNB401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	GLY A  66 GLU A 101 LYS A 102 ASP A 156	None	0.61A	5mvsB-3pvcA: 8.3	5mvsB-3pvcA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OY0_1_PQN1842_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	PHE A  67 ARG A 128 ALA A 124 LEU A 127 LEU A  92	None	1.26A	5oy01-3pvcA: undetectable 5oy07-3pvcA: undetectable	5oy01-3pvcA: 8.58 5oy07-3pvcA: 4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_A_ACTA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 5	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.09A	5vunA-3pvcA: undetectable	5vunA-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUN_B_ACTB804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 4	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.09A	5vunB-3pvcA: 0.0	5vunB-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUO_A_ACTA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 4	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.12A	5vuoA-3pvcA: 0.2	5vuoA-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_A_SAMA601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.93A	5wz1A-3pvcA: 4.0	5wz1A-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_C_SAMC601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.92A	5wz1C-3pvcA: 5.2	5wz1C-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_D_SAMD601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.95A	5wz1D-3pvcA: 4.8	5wz1D-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_E_SAME601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.93A	5wz1E-3pvcA: 4.9	5wz1E-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_F_SAMF601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.97A	5wz1F-3pvcA: 5.2	5wz1F-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_G_SAMG601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.95A	5wz1G-3pvcA: 4.9	5wz1G-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_H_SAMH601_0 (NS5 METHYLTRANSFERASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.90A	5wz1H-3pvcA: 5.1	5wz1H-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_A_SAMA601_0 (NS5 MTASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  68 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.81A	5wz2A-3pvcA: 3.6	5wz2A-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_A_SAMA601_0 (NS5 MTASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.87A	5wz2A-3pvcA: 3.6	5wz2A-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_B_SAMB601_0 (NS5 MTASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  68 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.90A	5wz2B-3pvcA: 6.2	5wz2B-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ2_B_SAMB601_0 (NS5 MTASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	6 / 12	GLY A  66 GLY A  70 LYS A 102 ASP A 156 VAL A 157 ASP A 178	None	0.91A	5wz2B-3pvcA: 6.2	5wz2B-3pvcA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XU8_A_DX4A701_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 8	GLY A 393 LEU A 394 SER A 497 GLN A 498	None	0.90A	5xu8A-3pvcA: undetectable	5xu8A-3pvcA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AOG_A_CP6A704_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.12A	6aogA-3pvcA: undetectable	6aogA-3pvcA: 7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AOG_B_CP6B704_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	VAL A 614 ALA A 253 ASP A 166 TYR A 594 THR A 252	None	1.15A	6aogB-3pvcA: 2.0	6aogB-3pvcA: 7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_A_ACTA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	3 / 3	GLN A 308 TRP A 408 VAL A 502	None	1.08A	6auuA-3pvcA: undetectable	6auuA-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_A_ACTA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	3 / 3	GLN A 474 TRP A 445 VAL A 461	None	1.14A	6auuA-3pvcA: undetectable	6auuA-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AUU_B_ACTB804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 4	GLY A 309 GLN A 308 TRP A 408 VAL A 502	CL  A 691 (-3.5A) None None None	1.05A	6auuB-3pvcA: 0.0	6auuB-3pvcA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F5U_A_CQNA610_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN,GP1 ENVELOPE GLYCOPROTEIN)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	5 / 10	VAL A 461 ALA A 268 LEU A 435 THR A 291 LEU A 438	None None FAD  A 690 (-4.6A) None None	0.97A	6f5uA-3pvcA: undetectable 6f5uB-3pvcA: undetectable	6f5uA-3pvcA: 8.18 6f5uB-3pvcA: 9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	3pvc	TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC (Yersinia pestis)	4 / 6	PHE A 225 LEU A 220 ALA A 223 THR A  65	None	0.89A	6f88A-3pvcA: undetectable	6f88A-3pvcA: 8.89