SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LOQ_A_ACTA279_0 (UNIVERSAL STRESS PROTEIN)	3pvo	C-REACTIVE PROTEIN (Homo sapiens)	4 / 4	SER A 151 SER A 18 THR A 17 SER A 15	None	1.33A	3loqA-3pvoA: undetectable	3loqA-3pvoA: 23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RET_A_SALA201_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	3pvo	C-REACTIVE PROTEIN (Homo sapiens)	5 / 10	VAL A 127 ALA A 24 VAL A 184 MET A 161 ILE A 63	None	1.48A	3retA-3pvoA: undetectable 3retB-3pvoA: undetectable	3retA-3pvoA: 16.99 3retB-3pvoA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6N_A_T1CA392_1 (TETX2 PROTEIN)	3pvo	C-REACTIVE PROTEIN (Homo sapiens)	5 / 11	GLN A 139 PHE A 142 GLY A 143 ALA A 129 GLY A 128	None	0.96A	4a6nA-3pvoA: undetectable	4a6nA-3pvoA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEN_B_VDYB201_2 (CDL2.2)	3pvo	C-REACTIVE PROTEIN (Homo sapiens)	5 / 12	LEU A 190 MET A 4 ILE A 156 TYR A 54 LEU A 135	None	1.22A	5ienB-3pvoA: undetectable	5ienB-3pvoA: 21.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LOQ_A_ACTA279_0","UNIVERSAL STRESS PROTEIN","3pvo","C-REACTIVE PROTEIN","Homo sapiens",4,"SER A 151;SER A  18;THR A  17;SER A  15","None","1.33A","3loqA-3pvoA:undetectable","3loqA-3pvoA:23.47"],["3RET_A_SALA201_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB;SALICYLATE BIOSYNTHESIS PROTEIN PCHB","3pvo","C-REACTIVE PROTEIN","Homo sapiens",5,"VAL A 127;ALA A  24;VAL A 184;MET A 161;ILE A  63","None","1.48A","3retA-3pvoA:undetectable;3retB-3pvoA:undetectable","3retA-3pvoA:16.99;3retB-3pvoA:16.99"],["4A6N_A_T1CA392_1","TETX2 PROTEIN","3pvo","C-REACTIVE PROTEIN","Homo sapiens",5,"GLN A 139;PHE A 142;GLY A 143;ALA A 129;GLY A 128","None","0.96A","4a6nA-3pvoA:undetectable","4a6nA-3pvoA:20.75"],["5IEN_B_VDYB201_2","CDL2.2","3pvo","C-REACTIVE PROTEIN","Homo sapiens",5,"LEU A 190;MET A   4;ILE A 156;TYR A  54;LEU A 135","None","1.22A","5ienB-3pvoA:undetectable","5ienB-3pvoA:21.36"]]