SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 414
THR A 415
ALA A 418
ARG A 504
 None
 0.58A 2ql8A-3pvvA:
undetectable
2ql8B-3pvvA:
undetectable		 2ql8A-3pvvA:
21.48
2ql8B-3pvvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		5 / 9 ILE A 462
GLY A 463
GLY A 467
SER A 412
CYH A 451
 None
 0.94A 2qmmA-3pvvA:
undetectable		 2qmmA-3pvvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 457
ILE A 462
GLY A 463
SER A 412
CYH A 451
 None
 1.08A 2qmmA-3pvvA:
undetectable		 2qmmA-3pvvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		5 / 11 ILE A 462
GLY A 463
GLY A 467
SER A 412
CYH A 451
 None
 0.89A 2qmmA-3pvvA:
undetectable
2qmmB-3pvvA:
undetectable		 2qmmA-3pvvA:
20.69
2qmmB-3pvvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		4 / 7 ARG A 502
ALA A 447
VAL A 473
ILE A 416
 None
 0.97A 3wsjB-3pvvA:
undetectable		 3wsjB-3pvvA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3pvv CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Mycobacterium
tuberculosis) 		3 / 3 LEU A 497
ILE A 501
ARG A 504
 None
 0.70A 4mk4B-3pvvA:
undetectable		 4mk4B-3pvvA:
14.78