SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pw9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 LEU A 194
PRO A 230
ILE A 226
LEU A 222
 None
 1.16A 1ya4C-3pw9A:
undetectable		 1ya4C-3pw9A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PHE A 132
TYR A 216
VAL A 100
ALA A 224
LEU A 122
 None
GOL  A 302 ( 4.3A)
SER  A 305 (-4.5A)
None
None
 1.28A 2x2nC-3pw9A:
undetectable		 2x2nC-3pw9A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 ILE A  89
VAL A 168
GLY A 177
VAL A 106
LEU A 138
 None
 1.17A 3elzC-3pw9A:
undetectable		 3elzC-3pw9A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A  93
ILE A 133
VAL A 169
TYR A 156
LEU A  90
 None
None
None
None
GOL  A 303 ( 4.7A)
 1.14A 4a81A-3pw9A:
undetectable		 4a81A-3pw9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 VAL A 189
ILE A 226
LEU A 115
LEU A 119
 None
 0.83A 4l1wA-3pw9A:
undetectable		 4l1wA-3pw9A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 122
GLY A 166
ASN A 131
ALA A 219
VAL A 189
 None
 1.26A 5kbwB-3pw9A:
1.6		 5kbwB-3pw9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 107
LEU A 115
ALA A 219
PHE A 132
LEU A 202
 None
 1.11A 5nd7B-3pw9A:
undetectable		 5nd7B-3pw9A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 166
PRO A 183
ALA A 184
PHE A 132
VAL A 151
 None
 1.23A 5x6yA-3pw9A:
undetectable		 5x6yA-3pw9A:
11.10