SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 4 THR A 177
LEU A 178
VAL A  27
LEU A   4
 None
 1.12A 1fbmB-3pwvA:
undetectable		 1fbmB-3pwvA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 6 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.33A 1kiaA-3pwvA:
undetectable		 1kiaA-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 6 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.33A 1kiaB-3pwvA:
undetectable		 1kiaB-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 7 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.33A 1kiaC-3pwvA:
0.5		 1kiaC-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 7 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.33A 1kiaD-3pwvA:
undetectable		 1kiaD-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 6 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.34A 1nbhA-3pwvA:
0.0		 1nbhA-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 7 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.34A 1nbhB-3pwvA:
1.0		 1nbhB-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 6 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.34A 1nbhC-3pwvA:
1.0		 1nbhC-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 7 ASN A  62
TYR A   6
TYR A 170
TYR A  58
 None
 1.34A 1nbhD-3pwvA:
1.0		 1nbhD-3pwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 5 ALA A  70
TYR A  66
ALA A  10
TYR A   8
 None
 1.02A 1xl6A-3pwvA:
3.1
1xl6B-3pwvA:
3.3		 1xl6A-3pwvA:
22.36
1xl6B-3pwvA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 12 ALA A 139
ALA A 138
GLN A 140
ALA A 134
LEU A  81
 None
 0.99A 2aclA-3pwvA:
undetectable
2aclE-3pwvA:
undetectable		 2aclA-3pwvA:
22.07
2aclE-3pwvA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 7 ARG A  64
TYR A  66
TYR A   6
TYR A   8
 None
 1.17A 2ajvH-3pwvA:
12.1
2ajvL-3pwvA:
12.8		 2ajvH-3pwvA:
22.03
2ajvL-3pwvA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 5 LEU A 246
ASP A 226
PRO A 249
VAL A 248
 None
 0.95A 2aoiB-3pwvA:
undetectable		 2aoiB-3pwvA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 4 ALA A  70
TYR A  66
ALA A  10
TYR A   8
 None
 0.96A 2wlkA-3pwvA:
3.4
2wlkB-3pwvA:
3.1		 2wlkA-3pwvA:
22.36
2wlkB-3pwvA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 8 TYR A 122
TYR A  83
TYR A 117
HIS A  92
 None
 0.91A 2zm8A-3pwvA:
undetectable		 2zm8A-3pwvA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 8 TYR A 122
TYR A  83
TYR A 117
HIS A  92
 None
 0.96A 2zmaA-3pwvA:
undetectable		 2zmaA-3pwvA:
24.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 10 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.22A 3uprA-3pwvA:
34.2		 3uprA-3pwvA:
79.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 10 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.22A 3uprC-3pwvA:
34.3		 3uprC-3pwvA:
79.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 10 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.18A 3vriA-3pwvA:
34.2
3vriC-3pwvA:
undetectable		 3vriA-3pwvA:
79.56
3vriC-3pwvA:
3.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 12 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.18A 3vrjA-3pwvA:
34.3
3vrjC-3pwvA:
undetectable		 3vrjA-3pwvA:
79.56
3vrjC-3pwvA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		3 / 3 ARG A   5
GLU A 211
TYR A 101
 None
 0.67A 4r29D-3pwvA:
undetectable		 4r29D-3pwvA:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		3 / 3 PRO A  46
ARG A  47
GLU A  52
 None
 0.74A 5j6hA-3pwvA:
34.0		 5j6hA-3pwvA:
74.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		4 / 8 TYR A   8
TYR A  66
ILE A  65
ILE A  72
 None
 0.92A 5mzrE-3pwvA:
undetectable		 5mzrE-3pwvA:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 10 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.19A 5u98A-3pwvA:
34.4		 5u98A-3pwvA:
79.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 10 TYR A   8
TYR A  98
TYR A 122
ILE A 123
TRP A 146
 None
 0.18A 5u98D-3pwvA:
34.4		 5u98D-3pwvA:
79.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 12 LEU A 129
LEU A 159
GLY A 161
VAL A 164
LEU A 110
 None
 1.12A 5uc1A-3pwvA:
undetectable		 5uc1A-3pwvA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3pwv MHC CLASS I ANTIGEN
(Bos
taurus) 		5 / 12 LEU A 129
LEU A 159
GLY A 161
VAL A 164
LEU A 110
 None
 1.15A 5uc1B-3pwvA:
undetectable		 5uc1B-3pwvA:
13.14