SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_1
(PHOSPHOLIPASE A2)		 3pwx PUTATIVE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 SER A 205
PRO A 206
PHE A 208
PRO A 204
 None
 1.46A 3bjwA-3pwxA:
1.9		 3bjwA-3pwxA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_2
(PHOSPHOLIPASE A2)		 3pwx PUTATIVE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 SER A 205
PRO A 206
PHE A 208
PRO A 204
 None
 1.48A 3bjwG-3pwxA:
1.8		 3bjwG-3pwxA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_1
(PHOSPHOLIPASE A2)		 3pwx PUTATIVE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 SER A 205
PRO A 206
PHE A 208
PRO A 204
 None
 1.49A 3bjwD-3pwxA:
1.9		 3bjwD-3pwxA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3pwx PUTATIVE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 ARG A 236
GLN A  76
GLY A 138
GLY A 157
ALA A 145
 None
 1.18A 3tegA-3pwxA:
undetectable		 3tegA-3pwxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3pwx PUTATIVE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 LEU A  49
VAL A 254
ASP A 255
 None
 0.49A 4y8wC-3pwxA:
1.4		 4y8wC-3pwxA:
19.63