SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3py6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 5 HIS A  86
HIS A 219
HIS A 241
HIS A  91
 MN  A 301 (-3.4A)
5GP  A 303 (-4.1A)
MN  A 300 ( 3.4A)
MN  A 300 (-3.4A)
 0.92A 1e9yB-3py6A:
undetectable		 1e9yB-3py6A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 5 ASP A 188
HIS A 170
HIS A 241
HIS A 219
 MN  A 300 (-2.5A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
5GP  A 303 (-4.1A)
 1.21A 1ei6A-3py6A:
undetectable		 1ei6A-3py6A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 ASP A  90
HIS A 170
HIS A 241
HIS A 219
 MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
5GP  A 303 (-4.1A)
 1.00A 1ei6C-3py6A:
undetectable		 1ei6C-3py6A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 7 TYR A 185
THR A 187
GLY A  16
ASP A  62
 None
 0.84A 2a1mA-3py6A:
undetectable		 2a1mA-3py6A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 TYR A 185
THR A 187
GLY A  16
ASP A  62
 None
 0.83A 2a1oA-3py6A:
undetectable		 2a1oA-3py6A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 7 ARG A  41
LEU A  13
PRO A   4
VAL A  76
 None
 1.23A 2hrcA-3py6A:
undetectable		 2hrcA-3py6A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 ASP A 188
ASP A  90
LEU A 211
HIS A 243
 MN  A 300 (-2.5A)
MN  A 300 ( 2.6A)
None
TAR  A 304 (-4.2A)
 0.96A 2q0iA-3py6A:
10.3		 2q0iA-3py6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 11 ASP A  90
HIS A  91
HIS A 170
ASP A 188
HIS A 241
 MN  A 300 ( 2.6A)
MN  A 300 (-3.4A)
MN  A 301 ( 3.4A)
MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
 0.82A 2q0jB-3py6A:
10.2		 2q0jB-3py6A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 11 ASP A  90
HIS A  91
HIS A 170
ASP A 188
HIS A 243
 MN  A 300 ( 2.6A)
MN  A 300 (-3.4A)
MN  A 301 ( 3.4A)
MN  A 300 (-2.5A)
TAR  A 304 (-4.2A)
 1.29A 2q0jB-3py6A:
10.2		 2q0jB-3py6A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 5 HIS A 170
HIS A 219
HIS A 241
ASP A  90
 MN  A 301 ( 3.4A)
5GP  A 303 (-4.1A)
MN  A 300 ( 3.4A)
MN  A 300 ( 2.6A)
 1.15A 3c0zA-3py6A:
undetectable		 3c0zA-3py6A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 4 VAL A  47
ARG A 162
ILE A 146
THR A  57
 None
 1.38A 3cl9A-3py6A:
undetectable		 3cl9A-3py6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 10 HIS A  86
HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 (-3.4A)
MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.72A 4c1dB-3py6A:
10.3		 4c1dB-3py6A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 11 HIS A  86
HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 (-3.4A)
MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.73A 4c1fA-3py6A:
9.9
4c1fB-3py6A:
10.5		 4c1fA-3py6A:
22.03
4c1fB-3py6A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 9 HIS A  86
HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 (-3.4A)
MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.73A 4c1hA-3py6A:
11.4		 4c1hA-3py6A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.71A 4exsB-3py6A:
10.6		 4exsB-3py6A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 5 HIS A  86
HIS A 219
HIS A 241
HIS A  91
 MN  A 301 (-3.4A)
5GP  A 303 (-4.1A)
MN  A 300 ( 3.4A)
MN  A 300 (-3.4A)
 0.97A 4h9mA-3py6A:
undetectable		 4h9mA-3py6A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 7 THR A 240
GLY A 209
VAL A 189
HIS A  91
 None
None
None
MN  A 300 (-3.4A)
 0.92A 4qwpB-3py6A:
undetectable		 4qwpB-3py6A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.71A 5a5zA-3py6A:
10.1		 5a5zA-3py6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		6 / 11 HIS A  86
HIS A  88
ASP A  90
HIS A  91
HIS A 170
HIS A 241
 MN  A 301 (-3.4A)
MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 300 (-3.4A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.40A 5ayaA-3py6A:
10.9		 5ayaA-3py6A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 12 LEU A  45
LEU A 141
THR A  63
ILE A  95
GLY A  14
 None
 0.90A 5d4uC-3py6A:
undetectable		 5d4uC-3py6A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 PHE A 220
SER A 218
HIS A 170
LEU A 211
 None
5GP  A 303 ( 4.3A)
MN  A 301 ( 3.4A)
None
 1.18A 5dzka-3py6A:
undetectable
5dzko-3py6A:
undetectable		 5dzka-3py6A:
23.96
5dzko-3py6A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 7 PHE A 220
SER A 218
HIS A 170
LEU A 211
 None
5GP  A 303 ( 4.3A)
MN  A 301 ( 3.4A)
None
 1.11A 5dzkD-3py6A:
undetectable
5dzkR-3py6A:
undetectable		 5dzkD-3py6A:
23.96
5dzkR-3py6A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 PHE A 220
SER A 218
HIS A 170
LEU A 211
 None
5GP  A 303 ( 4.3A)
MN  A 301 ( 3.4A)
None
 1.24A 5dzke-3py6A:
undetectable
5dzks-3py6A:
undetectable		 5dzke-3py6A:
23.96
5dzks-3py6A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 PHE A 220
SER A 218
HIS A 170
LEU A 211
 None
5GP  A 303 ( 4.3A)
MN  A 301 ( 3.4A)
None
 1.24A 5dzkg-3py6A:
undetectable
5dzku-3py6A:
undetectable		 5dzkg-3py6A:
23.96
5dzku-3py6A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 9 ILE A  61
PHE A 178
THR A 240
ASP A 188
 None
None
None
MN  A 300 (-2.5A)
 0.98A 5lg3I-3py6A:
undetectable		 5lg3I-3py6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 ASP A 188
HIS A 170
HIS A  86
HIS A 241
 MN  A 300 (-2.5A)
MN  A 301 ( 3.4A)
MN  A 301 (-3.4A)
MN  A 300 ( 3.4A)
 0.90A 5ncdA-3py6A:
undetectable
5ncdD-3py6A:
2.0		 5ncdA-3py6A:
22.60
5ncdD-3py6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 ASP A 188
HIS A 170
HIS A  86
HIS A 241
 MN  A 300 (-2.5A)
MN  A 301 ( 3.4A)
MN  A 301 (-3.4A)
MN  A 300 ( 3.4A)
 0.91A 5ncdB-3py6A:
undetectable
5ncdC-3py6A:
undetectable		 5ncdB-3py6A:
22.60
5ncdC-3py6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 HIS A 170
HIS A  86
ARG A  42
HIS A 241
 MN  A 301 ( 3.4A)
MN  A 301 (-3.4A)
None
MN  A 300 ( 3.4A)
 0.74A 5nekB-3py6A:
undetectable		 5nekB-3py6A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 8 ASP A 188
HIS A 170
HIS A  86
ARG A  42
HIS A 241
 MN  A 300 (-2.5A)
MN  A 301 ( 3.4A)
MN  A 301 (-3.4A)
None
MN  A 300 ( 3.4A)
 0.93A 5nekD-3py6A:
undetectable		 5nekD-3py6A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 ASP A 188
HIS A 241
HIS A 219
HIS A  86
 MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
5GP  A 303 (-4.1A)
MN  A 301 (-3.4A)
 0.92A 5nekD-3py6A:
undetectable		 5nekD-3py6A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 ASP A 188
HIS A 170
HIS A  86
HIS A 241
 MN  A 300 (-2.5A)
MN  A 301 ( 3.4A)
MN  A 301 (-3.4A)
MN  A 300 ( 3.4A)
 0.89A 5nelA-3py6A:
undetectable
5nelD-3py6A:
undetectable		 5nelA-3py6A:
22.60
5nelD-3py6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		6 / 10 HIS A  86
HIS A  88
HIS A  91
HIS A 170
ASP A 188
HIS A 219
 MN  A 301 (-3.4A)
MN  A 301 ( 3.3A)
MN  A 300 (-3.4A)
MN  A 301 ( 3.4A)
MN  A 300 (-2.5A)
5GP  A 303 (-4.1A)
 0.29A 5nzwA-3py6A:
10.7		 5nzwA-3py6A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		3 / 3 HIS A  91
ASP A 188
HIS A 241
 MN  A 300 (-3.4A)
MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
 0.71A 5oexA-3py6A:
undetectable		 5oexA-3py6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		3 / 3 HIS A  91
ASP A 188
HIS A 241
 MN  A 300 (-3.4A)
MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
 0.72A 5oexB-3py6A:
undetectable		 5oexB-3py6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		3 / 3 HIS A  91
ASP A 188
HIS A 241
 MN  A 300 (-3.4A)
MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
 0.71A 5oexC-3py6A:
undetectable		 5oexC-3py6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		3 / 3 HIS A  91
ASP A 188
HIS A 241
 MN  A 300 (-3.4A)
MN  A 300 (-2.5A)
MN  A 300 ( 3.4A)
 0.70A 5oexD-3py6A:
undetectable		 5oexD-3py6A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 8 HIS A  88
ASP A  90
HIS A 170
HIS A 241
 MN  A 301 ( 3.3A)
MN  A 300 ( 2.6A)
MN  A 301 ( 3.4A)
MN  A 300 ( 3.4A)
 0.74A 5zj8A-3py6A:
10.2		 5zj8A-3py6A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		4 / 6 GLY A 181
VAL A  59
PHE A 178
PHE A 152
 None
 1.01A 6h7lB-3py6A:
undetectable		 6h7lB-3py6A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 12 THR A  63
VAL A  60
VAL A  59
ASP A  96
VAL A 102
 None
 1.48A 6iblA-3py6A:
undetectable		 6iblA-3py6A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3py6 BETA-LACTAMASE-LIKE
(Brucella
abortus) 		5 / 12 THR A  63
VAL A  60
VAL A  59
ASP A  96
VAL A 102
 None
 1.45A 6iblB-3py6A:
undetectable		 6iblB-3py6A:
19.57