SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3pyw S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 6 PHE A  66
ILE A  78
VAL A  81
ALA A  47
 None
 0.93A 2j5mA-3pywA:
undetectable		 2j5mA-3pywA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 3pyw S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		5 / 12 SER A 104
ALA A 106
LEU A 109
ALA A  44
VAL A  81
 None
 1.25A 2yvlC-3pywA:
undetectable		 2yvlC-3pywA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3pyw S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 4 ASN A  30
GLY A  33
ASP A  16
ASP A   7
 None
None
SO4  A 204 (-3.9A)
None
 1.32A 4n49A-3pywA:
undetectable		 4n49A-3pywA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3pyw S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 7 ASP A   7
PRO A   6
PHE A   5
ASN A  30
 None
 1.14A 5l1fC-3pywA:
undetectable		 5l1fC-3pywA:
13.94