SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pzd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3pzd MYOSIN-X
(Homo
sapiens) 		4 / 7 ASN A1615
TYR A1527
ASN A1530
VAL A1523
 None
 1.29A 1wu8A-3pzdA:
undetectable
1wu8C-3pzdA:
undetectable		 1wu8A-3pzdA:
19.56
1wu8C-3pzdA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3pzd MYOSIN-X
(Homo
sapiens) 		3 / 3 GLN A1594
HIS A1597
ARG A1682
 None
 0.90A 1zlqA-3pzdA:
undetectable		 1zlqA-3pzdA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_1
(MNMC2)		 3pzd MYOSIN-X
(Homo
sapiens) 		4 / 4 GLU A1746
ASP A1763
ASP A2028
GLU A1683
 None
 1.26A 3vywB-3pzdA:
undetectable		 3vywB-3pzdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3pzd MYOSIN-X
(Homo
sapiens) 		3 / 3 GLU A1690
THR A1679
HIS A1719
 None
 0.81A 4q15A-3pzdA:
undetectable		 4q15A-3pzdA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3pzd MYOSIN-X
(Homo
sapiens) 		3 / 3 GLU A1690
THR A1679
HIS A1719
 None
 0.80A 4q15B-3pzdA:
undetectable		 4q15B-3pzdA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3pzd MYOSIN-X
(Homo
sapiens) 		4 / 5 ARG A1989
GLY A1988
GLU A1987
SER A1976
 None
 1.26A 4z3oA-3pzdA:
undetectable
4z3oB-3pzdA:
undetectable		 4z3oA-3pzdA:
21.17
4z3oB-3pzdA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3pzd MYOSIN-X
(Homo
sapiens) 		5 / 12 LEU A1649
ILE A1645
GLY A1644
LEU A1676
LEU A1640
 None
 1.26A 5nfjC-3pzdA:
undetectable		 5nfjC-3pzdA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3pzd MYOSIN-X
(Homo
sapiens) 		4 / 8 LEU A1838
VAL A1854
ARG A1834
ILE A1924
 None
 0.99A 5v0vA-3pzdA:
undetectable		 5v0vA-3pzdA:
22.44