SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 0.99A 5n0oA-3pzjA:
undetectable		 5n0oA-3pzjA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 1.00A 5n0oB-3pzjA:
undetectable		 5n0oB-3pzjA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 1.03A 5n0rA-3pzjA:
undetectable		 5n0rA-3pzjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 1.05A 5n0wA-3pzjA:
undetectable		 5n0wA-3pzjA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 1.01A 5n0xA-3pzjA:
undetectable		 5n0xA-3pzjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 12 TYR A  91
GLY A 106
HIS A 121
VAL A  83
ALA A 145
 None
None
EDO  A 207 (-4.0A)
NA  A 301 (-4.3A)
None
 1.03A 5n0xB-3pzjA:
undetectable		 5n0xB-3pzjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A
HETERODISULFIDE
REDUCTASE, SUBUNIT B
HETERODISULFIDE
REDUCTASE, SUBUNIT C)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		4 / 4 GLU A 154
ARG A 156
ARG A 108
GLU A 118
 None
None
None
EDO  A 207 ( 4.8A)
 1.49A 5odcB-3pzjA:
0.0
5odcC-3pzjA:
0.0
5odcG-3pzjA:
0.9		 5odcB-3pzjA:
20.52
5odcC-3pzjA:
21.03
5odcG-3pzjA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3pzj PROBABLE
ACETYLTRANSFERASES
(Chromobacterium
violaceum) 		5 / 10 PHE A  75
ALA A  80
LEU A  79
GLY A  47
ILE A 119
 None
 1.18A 5oy01-3pzjA:
undetectable
5oy07-3pzjA:
undetectable		 5oy01-3pzjA:
16.92
5oy07-3pzjA:
10.66