SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pzs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 5 PRO A 218
VAL A 221
TYR A 263
GLU A 264
 None
SO4  A 288 (-4.2A)
None
None
 1.45A 1m8dA-3pzsA:
undetectable		 1m8dA-3pzsA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 5 PRO A 218
VAL A 221
TYR A 263
GLU A 264
 None
SO4  A 288 (-4.2A)
None
None
 1.46A 1m8dB-3pzsA:
undetectable		 1m8dB-3pzsA:
19.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_A_PXLA288_1
(PYRIDOXAMINE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		8 / 10 SER A   9
ALA A  16
HIS A  43
THR A  44
GLN A  45
TYR A  82
VAL A 219
ASP A 223
 None
None
None
None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.93A 1td2A-3pzsA:
46.6		 1td2A-3pzsA:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_A_PXLA288_1
(PYRIDOXAMINE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		8 / 10 SER A   9
VAL A  11
ALA A  16
HIS A  43
THR A  44
GLN A  45
VAL A 219
ASP A 223
 None
None
None
None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.57A 1td2A-3pzsA:
46.6		 1td2A-3pzsA:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_B_PXLB289_1
(PYRIDOXAMINE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		7 / 9 ALA A  16
HIS A  43
THR A  44
TYR A  82
VAL A 113
VAL A 219
ASP A 223
 None
None
None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.81A 1td2B-3pzsA:
46.4		 1td2B-3pzsA:
74.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD2_B_PXLB289_1
(PYRIDOXAMINE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		6 / 9 SER A   9
ALA A  16
HIS A  43
THR A  44
VAL A 219
ASP A 223
 None
None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.68A 1td2B-3pzsA:
46.4		 1td2B-3pzsA:
74.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 7 ILE A  92
GLN A  98
LEU A  72
LEU A  35
 None
 1.03A 2qqcB-3pzsA:
undetectable
2qqcC-3pzsA:
undetectable		 2qqcB-3pzsA:
16.26
2qqcC-3pzsA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 7 LEU A  72
LEU A  35
ILE A  92
GLN A  98
 None
 1.05A 2qqcA-3pzsA:
undetectable
2qqcF-3pzsA:
undetectable		 2qqcA-3pzsA:
11.31
2qqcF-3pzsA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 7 LEU A  72
LEU A  35
ILE A  92
GLN A  98
 None
 1.04A 2qqcG-3pzsA:
undetectable
2qqcJ-3pzsA:
undetectable		 2qqcG-3pzsA:
11.31
2qqcJ-3pzsA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 7 LEU A  72
LEU A  35
ILE A  92
GLN A  98
 None
 1.05A 2qqcI-3pzsA:
undetectable
2qqcL-3pzsA:
undetectable		 2qqcI-3pzsA:
11.31
2qqcL-3pzsA:
16.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		4 / 4 SER A   9
HIS A  43
THR A  44
VAL A 219
 None
None
None
SO4  A 288 (-3.6A)
 0.45A 3fhxA-3pzsA:
40.9		 3fhxA-3pzsA:
31.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		7 / 8 SER A   9
VAL A  38
PHE A  40
HIS A  43
THR A  44
TYR A  82
VAL A 219
 None
None
BME  A 290 (-4.2A)
None
None
None
SO4  A 288 (-3.6A)
 0.59A 3fhxB-3pzsA:
40.4		 3fhxB-3pzsA:
31.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 219
GLN A  45
VAL A  38
ASN A  18
GLY A  17
 SO4  A 288 (-3.6A)
None
None
None
None
 1.37A 3km6B-3pzsA:
undetectable		 3km6B-3pzsA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.80A 3mbhA-3pzsA:
34.3		 3mbhA-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.92A 3mbhA-3pzsA:
34.3		 3mbhA-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.42A 3mbhA-3pzsA:
34.3		 3mbhA-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.77A 3mbhB-3pzsA:
34.2		 3mbhB-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.87A 3mbhB-3pzsA:
34.2		 3mbhB-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.37A 3mbhB-3pzsA:
34.2		 3mbhB-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.73A 3mbhC-3pzsA:
34.4		 3mbhC-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.89A 3mbhC-3pzsA:
34.4		 3mbhC-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.39A 3mbhC-3pzsA:
34.4		 3mbhC-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.76A 3mbhD-3pzsA:
34.2		 3mbhD-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.89A 3mbhD-3pzsA:
34.2		 3mbhD-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.44A 3mbhD-3pzsA:
34.2		 3mbhD-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.76A 3mbhE-3pzsA:
34.1		 3mbhE-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.87A 3mbhE-3pzsA:
34.1		 3mbhE-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.38A 3mbhE-3pzsA:
34.1		 3mbhE-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 HIS A  43
GLN A  45
TYR A  82
VAL A 113
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.75A 3mbhF-3pzsA:
34.2		 3mbhF-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 HIS A  43
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 0.89A 3mbhF-3pzsA:
34.2		 3mbhF-3pzsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 11 SER A   9
THR A  44
GLN A  45
TYR A  82
ASP A 223
 None
None
None
None
SO4  A 288 (-3.4A)
 1.41A 3mbhF-3pzsA:
34.2		 3mbhF-3pzsA:
25.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 5 SER A   9
GLY A  17
THR A  44
VAL A 219
ASP A 223
 None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.39A 4eohA-3pzsA:
40.4		 4eohA-3pzsA:
31.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 5 SER A   9
HIS A  43
TYR A  82
VAL A 219
ASP A 223
 None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.4A)
 0.41A 4eohB-3pzsA:
40.2		 4eohB-3pzsA:
31.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		3 / 3 PRO A  34
ASN A  36
HIS A  10
 None
 0.95A 4ma3H-3pzsA:
undetectable
4ma3L-3pzsA:
undetectable		 4ma3H-3pzsA:
21.22
4ma3L-3pzsA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 12 PRO A 175
LEU A 136
VAL A 178
GLY A 222
THR A 225
 None
None
None
SO4  A 288 (-3.4A)
None
 1.42A 4mubA-3pzsA:
undetectable		 4mubA-3pzsA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 PHE A 213
VAL A 267
GLY A 220
THR A 225
VAL A 253
 None
None
SO4  A 288 (-3.2A)
None
None
 0.94A 4r20B-3pzsA:
undetectable		 4r20B-3pzsA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		3 / 3 ARG A  26
PRO A  34
ASN A  36
 None
 1.02A 5jwaA-3pzsA:
3.3
5jwaH-3pzsA:
undetectable		 5jwaA-3pzsA:
19.49
5jwaH-3pzsA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.47A 5ksgB-3pzsA:
undetectable		 5ksgB-3pzsA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSN_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.50A 5ksnB-3pzsA:
undetectable		 5ksnB-3pzsA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.45A 5kt8B-3pzsA:
undetectable		 5kt8B-3pzsA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.50A 5sxsB-3pzsA:
undetectable		 5sxsB-3pzsA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_B_NIZB805_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.49A 5syiB-3pzsA:
undetectable		 5syiB-3pzsA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		3 / 3 GLU A 262
TYR A 263
ARG A 216
 BME  A 289 (-3.9A)
None
None
 0.77A 5uunA-3pzsA:
undetectable		 5uunA-3pzsA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CFQ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3pzs PYRIDOXAMINE KINASE
(Yersinia
pestis) 		5 / 9 VAL A 113
GLY A 227
SER A 226
GLN A   8
LEU A  79
 None
 1.48A 6cfqB-3pzsA:
0.5		 6cfqB-3pzsA:
19.16