SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 11 ALA A  94
GLY A  66
ASN A 134
HIS A 229
GLU A 165
 None
 1.45A 1n6cA-3pzuA:
undetectable		 1n6cA-3pzuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 8 ASP A 129
ASP A 195
TYR A 164
THR A 159
 None
 1.05A 2aouA-3pzuA:
undetectable		 2aouA-3pzuA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 10 GLU A 165
ARG A  92
TYR A  96
ILE A 132
GLU A 257
 None
 1.34A 2qeoB-3pzuA:
0.0		 2qeoB-3pzuA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 7 LEU A 271
SER A 274
THR A 260
VAL A 269
 None
 1.09A 2uz2A-3pzuA:
undetectable		 2uz2A-3pzuA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 ASN A 168
GLU A 169
HIS A 229
GLU A 257
TRP A 291
 None
 0.57A 2v3dA-3pzuA:
16.4		 2v3dA-3pzuA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		3 / 3 TYR A 231
GLU A 169
ASN A 134
 None
 0.86A 2y7hC-3pzuA:
undetectable		 2y7hC-3pzuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 ARG A  92
GLU A 165
TYR A 231
ASN A 168
HIS A 131
 None
 1.48A 3bjmB-3pzuA:
undetectable		 3bjmB-3pzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 7 VAL A 289
THR A 256
ILE A 127
ILE A 163
 None
 0.84A 3deuA-3pzuA:
undetectable		 3deuA-3pzuA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		3 / 3 HIS A 131
PHE A 148
PHE A 149
 None
 0.51A 3lk0D-3pzuA:
undetectable		 3lk0D-3pzuA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 0.99A 3nt1B-3pzuA:
undetectable		 3nt1B-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 8 PRO A 170
HIS A 131
ILE A 132
ILE A 166
 None
 0.90A 3sfeB-3pzuA:
undetectable
3sfeC-3pzuA:
undetectable		 3sfeB-3pzuA:
20.06
3sfeC-3pzuA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 9 SER A 208
THR A 206
ASN A 171
GLY A 172
ASP A 173
 None
 1.28A 3sfuA-3pzuA:
undetectable		 3sfuA-3pzuA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 6 HIS A 229
GLU A 257
ASP A 129
SER A  63
 None
 1.07A 4apjA-3pzuA:
undetectable
4apjP-3pzuA:
undetectable		 4apjA-3pzuA:
19.66
4apjP-3pzuA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 9 VAL A  57
ALA A  56
GLY A  40
SER A  43
GLY A  54
 None
 1.36A 4mmfA-3pzuA:
undetectable		 4mmfA-3pzuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 9 VAL A  57
ALA A  56
GLY A  40
SER A  43
GLY A  54
 None
 1.39A 4mmfB-3pzuA:
undetectable		 4mmfB-3pzuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 5 ASN A 168
HIS A 131
GLU A 165
THR A 256
 None
 1.43A 4p6sA-3pzuA:
undetectable		 4p6sA-3pzuA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.05A 4rrwA-3pzuA:
undetectable		 4rrwA-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.04A 4rrwB-3pzuA:
undetectable		 4rrwB-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.05A 4rrwC-3pzuA:
undetectable		 4rrwC-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.06A 4rrxA-3pzuA:
undetectable		 4rrxA-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.07A 4rrxB-3pzuA:
undetectable		 4rrxB-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.05A 4rrzA-3pzuA:
undetectable		 4rrzA-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.04A 4rrzB-3pzuA:
undetectable		 4rrzB-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 VAL A  74
LEU A  79
VAL A 126
ALA A  93
LEU A  67
 None
 1.05A 4rrzC-3pzuA:
undetectable		 4rrzC-3pzuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_ACTA504_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 4 ALA A 145
LYS A 146
TYR A 183
GLU A 186
 None
 1.24A 4rvgA-3pzuA:
0.0		 4rvgA-3pzuA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		3 / 3 ARG A 326
ASP A  85
TRP A  86
 None
 1.20A 4xdqA-3pzuA:
undetectable		 4xdqA-3pzuA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 6 GLY A 259
THR A 260
SER A 261
ASN A 290
 None
 0.83A 5k4pA-3pzuA:
undetectable		 5k4pA-3pzuA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		4 / 5 GLU A 298
GLY A 267
SER A 261
GLY A 233
 None
 1.00A 5kprA-3pzuA:
undetectable		 5kprA-3pzuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 10 SER A 321
GLY A 322
ILE A  88
LEU A 293
PHE A 148
 None
 1.24A 5zjiA-3pzuA:
undetectable
5zjiJ-3pzuA:
undetectable		 5zjiA-3pzuA:
13.27
5zjiJ-3pzuA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		3 / 3 THR A 285
ALA A  56
LYS A  55
 None
 0.68A 6fgcA-3pzuA:
undetectable		 6fgcA-3pzuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		3 / 3 THR A 285
ALA A  56
LYS A  55
 None
 0.67A 6fgdA-3pzuA:
undetectable		 6fgdA-3pzuA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 GLY A 100
GLY A 101
ASP A 135
GLN A 140
GLY A  66
 None
 1.16A 6gneA-3pzuA:
2.6		 6gneA-3pzuA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3pzu ENDOGLUCANASE
(Bacillus
subtilis) 		5 / 12 GLY A 100
GLY A 101
ASP A 135
GLN A 140
GLY A  66
 None
 1.16A 6gneB-3pzuA:
2.6		 6gneB-3pzuA:
22.08