SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3pzy MOG
(Mycobacterium
avium) 		4 / 6 ASP A  22
VAL A  44
PRO A  26
THR A  29
 None
 1.45A 2q6oB-3pzyA:
5.0		 2q6oB-3pzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 3pzy MOG
(Mycobacterium
avium) 		4 / 8 LEU A  67
SER A 102
VAL A 145
GLY A 144
 None
 1.08A 2qd5A-3pzyA:
5.7		 2qd5A-3pzyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 3pzy MOG
(Mycobacterium
avium) 		4 / 8 LEU A  67
SER A 102
VAL A 145
GLY A 144
 None
 1.09A 2qd5B-3pzyA:
5.7		 2qd5B-3pzyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3pzy MOG
(Mycobacterium
avium) 		4 / 8 THR A  13
GLY A  71
GLY A  70
ASP A  22
 None
 0.65A 4qvvK-3pzyA:
undetectable
4qvvL-3pzyA:
undetectable		 4qvvK-3pzyA:
21.96
4qvvL-3pzyA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3pzy MOG
(Mycobacterium
avium) 		4 / 8 THR A  13
GLY A  71
GLY A  70
ASP A  22
 None
 0.66A 4qvvY-3pzyA:
undetectable
4qvvZ-3pzyA:
undetectable		 4qvvY-3pzyA:
21.96
4qvvZ-3pzyA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pzy MOG
(Mycobacterium
avium) 		5 / 11 GLY A 118
CYH A 117
ALA A 149
LEU A 142
ILE A  66
 None
 1.12A 4xumB-3pzyA:
undetectable		 4xumB-3pzyA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3pzy MOG
(Mycobacterium
avium) 		6 / 10 ILE A  28
VAL A  51
ILE A  66
LEU A  55
PRO A  50
LEU A 142
 None
 1.39A 5ienB-3pzyA:
undetectable		 5ienB-3pzyA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pzy MOG
(Mycobacterium
avium) 		5 / 10 PRO A 132
LEU A 128
ASP A  47
ILE A  28
GLY A  25
 None
 1.25A 6dlzA-3pzyA:
undetectable
6dlzD-3pzyA:
5.7		 6dlzA-3pzyA:
18.71
6dlzD-3pzyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pzy MOG
(Mycobacterium
avium) 		5 / 10 ILE A  28
GLY A  25
PRO A 132
LEU A 128
ASP A  47
 None
 1.24A 6dlzB-3pzyA:
5.7
6dlzC-3pzyA:
undetectable		 6dlzB-3pzyA:
18.71
6dlzC-3pzyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pzy MOG
(Mycobacterium
avium) 		5 / 10 PRO A 132
LEU A 128
ASP A  47
ILE A  28
GLY A  25
 None
 1.25A 6dm1A-3pzyA:
undetectable
6dm1D-3pzyA:
5.7		 6dm1A-3pzyA:
18.71
6dm1D-3pzyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pzy MOG
(Mycobacterium
avium) 		5 / 10 ILE A  28
GLY A  25
PRO A 132
LEU A 128
ASP A  47
 None
 1.25A 6dm1B-3pzyA:
5.7
6dm1C-3pzyA:
undetectable		 6dm1B-3pzyA:
18.71
6dm1C-3pzyA:
18.71