SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		4 / 8 VAL A 135
VAL A 143
PHE A 234
VAL A 274
 None
 0.75A 3fhxB-3q06A:
undetectable		 3fhxB-3q06A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		3 / 3 TYR A 327
GLY A 325
ASP A 324
 None
 0.64A 3ou6C-3q06A:
undetectable		 3ou6C-3q06A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		3 / 3 GLN A 167
HIS A 168
ARG A 249
 None
 0.87A 4qyqA-3q06A:
undetectable		 4qyqA-3q06A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		3 / 3 GLN A 167
HIS A 168
ARG A 249
 None
 0.88A 4qyqB-3q06A:
undetectable		 4qyqB-3q06A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		4 / 6 VAL A 274
CYH A 238
CYH A 242
LEU A 194
 None
ZN  A   1 (-2.4A)
ZN  A   1 (-2.3A)
None
 1.09A 5hrqB-3q06A:
undetectable
5hrqI-3q06A:
undetectable
5hrqJ-3q06A:
undetectable		 5hrqB-3q06A:
10.55
5hrqI-3q06A:
6.10
5hrqJ-3q06A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		4 / 6 VAL A 274
CYH A 238
CYH A 242
LEU A 194
 None
ZN  A   1 (-2.4A)
ZN  A   1 (-2.3A)
None
 1.08A 5hrqH-3q06A:
undetectable
5hrqK-3q06A:
undetectable
5hrqL-3q06A:
undetectable		 5hrqH-3q06A:
10.55
5hrqK-3q06A:
6.10
5hrqL-3q06A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		4 / 8 LEU A 145
ILE A 255
ALA A 159
PHE A 234
 None
 0.86A 5m0oC-3q06A:
undetectable		 5m0oC-3q06A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q06 CELLULAR TUMOR
ANTIGEN P53
(Homo
sapiens) 		3 / 3 ARG A 158
PHE A 212
LEU A 206
 None
 0.71A 5x1bC-3q06A:
undetectable		 5x1bC-3q06A:
20.50