SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q08'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		3 / 3 ASP A 195
ASP A 193
ASN A 152
 None
 0.61A 2bm9D-3q08A:
undetectable		 2bm9D-3q08A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 5 PHE A  75
PHE A  77
PHE A  90
VAL A  99
 None
 1.19A 2lh6A-3q08A:
undetectable		 2lh6A-3q08A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 6 ARG A  67
PHE A  75
ILE A 243
PHE A  94
 None
 1.00A 2qeiA-3q08A:
undetectable		 2qeiA-3q08A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 4 LYS A  28
PHE A  27
PHE A  76
VAL A 146
 None
 1.28A 3rv5A-3q08A:
0.9
3rv5B-3q08A:
0.0		 3rv5A-3q08A:
16.67
3rv5B-3q08A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 4 VAL A 242
PHE A  77
PHE A  24
VAL A 146
 None
 1.17A 3rv5C-3q08A:
undetectable
3rv5D-3q08A:
undetectable		 3rv5C-3q08A:
16.67
3rv5D-3q08A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		5 / 10 PHE A  94
ALA A 103
PHE A  27
SER A  96
GLY A 100
 None
 1.41A 4xp1A-3q08A:
undetectable		 4xp1A-3q08A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		5 / 12 VAL A  99
THR A  97
LEU A 246
VAL A 242
PHE A  77
 None
 1.19A 6a94B-3q08A:
undetectable		 6a94B-3q08A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 6 GLY A  12
THR A  16
GLN A  17
TYR A  82
 None
 1.24A 6ag0A-3q08A:
undetectable		 6ag0A-3q08A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 6 GLY A  12
THR A  16
GLN A  17
TYR A  82
 None
 1.23A 6ag0C-3q08A:
undetectable		 6ag0C-3q08A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		3 / 3 TRP A 155
GLU A 154
GLU A 162
 HEM  A1000 ( 4.7A)
None
None
 0.83A 6fhwA-3q08A:
undetectable		 6fhwA-3q08A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3q08 CHLORITE DISMUTASE
(Dechloromonas
aromatica) 		4 / 5 ASN A 117
TYR A 186
GLY A 111
HIS A 187
 HEM  A1000 (-4.9A)
None
None
None
 1.07A 6gh9A-3q08A:
undetectable		 6gh9A-3q08A:
16.83