SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		4 / 8 ILE X 410
PHE X 511
LEU X 456
GLY X 430
 None
 0.95A 2vdbA-3q0cX:
undetectable		 2vdbA-3q0cX:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		4 / 4 ARG X 515
ASP X 396
GLY X 386
THR X 366
 None
 1.47A 3k4vB-3q0cX:
undetectable		 3k4vB-3q0cX:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		5 / 12 SER X 409
ALA X 407
TYR X 428
LEU X 513
ILE X 516
 None
 1.42A 3qt0A-3q0cX:
undetectable		 3qt0A-3q0cX:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		3 / 3 ASP X 418
GLY X 415
TYR X 428
 None
 0.66A 3w9tC-3q0cX:
undetectable		 3w9tC-3q0cX:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		3 / 3 ASP X 418
GLY X 415
TYR X 428
 None
 0.65A 3w9tG-3q0cX:
undetectable		 3w9tG-3q0cX:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		4 / 6 ARG X 470
LEU X 426
TYR X 492
SER X 423
 None
 1.11A 5phhA-3q0cX:
undetectable		 5phhA-3q0cX:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3q0c HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH5
(Arabidopsis
thaliana) 		5 / 9 GLY X 452
LEU X 456
ILE X 410
GLY X 394
ILE X 363
 None
 0.96A 5vkqC-3q0cX:
undetectable
5vkqD-3q0cX:
undetectable		 5vkqC-3q0cX:
7.23
5vkqD-3q0cX:
7.23