SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q0i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 7 PHE A 308
VAL A 248
VAL A 275
ILE A 273
 None
 0.95A 1p7rA-3q0iA:
undetectable		 1p7rA-3q0iA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		5 / 12 VAL A  89
ILE A 139
LEU A 152
CYH A 183
LEU A  23
 None
 1.24A 2jn3A-3q0iA:
undetectable		 2jn3A-3q0iA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 4 GLN A 298
PRO A 296
VAL A 297
GLU A 285
 None
 1.32A 3huoA-3q0iA:
undetectable		 3huoA-3q0iA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 8 GLU A 174
ILE A  30
VAL A  33
PHE A   9
 None
 1.02A 4dx7B-3q0iA:
undetectable		 4dx7B-3q0iA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 6 ILE A 159
ILE A 114
SER A 113
LEU A 172
 None
 0.92A 4m51A-3q0iA:
undetectable		 4m51A-3q0iA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 ARG A 304
TRP A 307
ILE A 289
 None
 1.05A 4mwxA-3q0iA:
undetectable		 4mwxA-3q0iA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA607_0
(ALPHA-AMYLASE)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 4 ARG A 117
SER A 127
ASP A 132
ASN A 203
 None
 1.13A 6ag0A-3q0iA:
0.6		 6ag0A-3q0iA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 3q0i METHIONYL-TRNA
FORMYLTRANSFERASE
(Vibrio
cholerae) 		4 / 5 GLU A  38
PRO A  37
THR A  35
GLN A  36
 None
 1.21A 6fgdA-3q0iA:
2.6		 6fgdA-3q0iA:
23.39