SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 3q13 SPONDIN-1
(Homo
sapiens) 		5 / 12 GLY A 263
PRO A 265
VAL A 266
ALA A 233
ALA A 287
 None
 1.06A 3p2kC-3q13A:
undetectable		 3p2kC-3q13A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 3q13 SPONDIN-1
(Homo
sapiens) 		4 / 5 ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
 1.49A 3w9tB-3q13A:
undetectable		 3w9tB-3q13A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 3q13 SPONDIN-1
(Homo
sapiens) 		4 / 5 ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
 1.50A 3w9tC-3q13A:
undetectable		 3w9tC-3q13A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF501_1
(HEMOLYTIC LECTIN
CEL-III)		 3q13 SPONDIN-1
(Homo
sapiens) 		4 / 4 ASP A 325
SER A 359
GLY A 360
TRP A 326
 CA  A 601 (-2.2A)
None
None
None
 1.50A 3w9tF-3q13A:
0.0		 3w9tF-3q13A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 3q13 SPONDIN-1
(Homo
sapiens) 		3 / 3 LEU A 350
MET A 320
TYR A 212
 None
None
NAG  A 502 ( 3.8A)
 0.93A 4p6xG-3q13A:
undetectable		 4p6xG-3q13A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3q13 SPONDIN-1
(Homo
sapiens) 		5 / 12 ALA A 401
LEU A 350
ALA A 233
ILE A 283
LEU A 209
 None
 0.88A 4r3aB-3q13A:
undetectable		 4r3aB-3q13A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 3q13 SPONDIN-1
(Homo
sapiens) 		5 / 12 LEU A 262
ILE A 235
THR A 357
ALA A 355
LEU A 317
 None
 1.23A 5ienB-3q13A:
undetectable		 5ienB-3q13A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3q13 SPONDIN-1
(Homo
sapiens) 		3 / 3 LEU A 379
SER A 381
PHE A 389
 None
 0.63A 6fgcA-3q13A:
undetectable		 6fgcA-3q13A:
21.40