SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		4 / 8 GLY A 167
PHE A 182
ILE A 174
SER A 172
 None
 1.03A 2a8tB-3q19A:
undetectable		 2a8tB-3q19A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		4 / 5 SER A 140
LEU A 185
GLY A 189
CYH A 193
 None
 1.18A 3aiaA-3q19A:
undetectable
3aiaB-3q19A:
undetectable		 3aiaA-3q19A:
21.62
3aiaB-3q19A:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		4 / 6 ARG A  37
PRO A  73
GLU A  85
SER A  86
 None
GSH  A 240 (-4.8A)
GSH  A 240 (-3.7A)
GSH  A 240 (-2.7A)
 0.81A 3vlnA-3q19A:
33.1		 3vlnA-3q19A:
64.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		5 / 12 SER A 172
PHE A 165
LEU A 158
GLY A 167
ASP A 175
 None
 1.09A 4pevC-3q19A:
undetectable		 4pevC-3q19A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		3 / 3 LYS A  45
ILE A  47
ILE A  24
 None
 0.70A 4y0qA-3q19A:
undetectable		 4y0qA-3q19A:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		5 / 6 GLU A  91
GLN A 113
LYS A 114
LEU A 117
LEU A 177
 None
 0.49A 5yvnA-3q19A:
32.9		 5yvnA-3q19A:
65.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2
(Homo
sapiens) 		3 / 3 ARG A 112
LEU A 116
PHE A 120
 None
 0.61A 6nknP-3q19A:
undetectable		 6nknP-3q19A:
22.34