SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 6 PRO A 249
PHE A 250
GLU A  31
VAL A  33
 None
 1.47A 1l2iB-3q1nA:
undetectable		 1l2iB-3q1nA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 7 LEU A  20
LEU A 121
PHE A  92
SER A  86
 None
None
None
NO3  A 297 (-4.1A)
 1.04A 1wrlE-3q1nA:
undetectable
1wrlF-3q1nA:
undetectable		 1wrlE-3q1nA:
19.91
1wrlF-3q1nA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		5 / 12 ALA A  11
TYR A 114
VAL A 123
GLY A  12
ILE A  13
 None
 1.38A 2dcfA-3q1nA:
undetectable		 2dcfA-3q1nA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 6 ILE A 240
ARG A 171
LEU A 209
LEU A 202
 None
 1.05A 2rlfA-3q1nA:
undetectable
2rlfD-3q1nA:
undetectable		 2rlfA-3q1nA:
8.39
2rlfD-3q1nA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		5 / 10 ILE A 228
ALA A 217
LEU A 238
LEU A 288
PHE A 145
 EDO  A 301 ( 4.5A)
None
None
None
None
 1.12A 2w9sD-3q1nA:
undetectable		 2w9sD-3q1nA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		5 / 12 PHE A  92
SER A  22
LEU A 121
VAL A 123
PHE A 141
 None
 1.25A 3u9fP-3q1nA:
undetectable
3u9fS-3q1nA:
undetectable		 3u9fP-3q1nA:
20.88
3u9fS-3q1nA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		5 / 12 LEU A  48
GLY A  53
GLN A  71
THR A 239
ILE A 208
 NO3  A 295 ( 3.8A)
NO3  A 296 ( 3.1A)
NO3  A 296 (-3.7A)
EDO  A 302 ( 4.9A)
None
 1.14A 4ok1A-3q1nA:
undetectable		 4ok1A-3q1nA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 4 LEU A 169
ILE A 187
PRO A 196
LEU A 160
 None
 1.12A 5eb3A-3q1nA:
undetectable		 5eb3A-3q1nA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 4 LEU A 169
ILE A 187
PRO A 196
LEU A 197
 None
 1.23A 5eb3A-3q1nA:
undetectable		 5eb3A-3q1nA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 5 PHE A  49
SER A  51
ASN A  97
GLN A  94
 None
 1.44A 5kpcA-3q1nA:
undetectable		 5kpcA-3q1nA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		5 / 10 GLU A  31
LEU A 110
ALA A  45
PHE A 141
LEU A 121
 None
 1.35A 5mm4B-3q1nA:
undetectable		 5mm4B-3q1nA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3q1n GALACTOSE MUTAROTASE
RELATED ENZYME
(Lactobacillus
paracasei) 		4 / 6 TYR A 237
GLU A 254
GLY A 258
GLY A 274
 None
EDO  A 302 (-2.9A)
None
None
 0.75A 5x7pB-3q1nA:
1.8		 5x7pB-3q1nA:
12.70