SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A1325
ARG A1339
ILE A1385
PHE A1360
 None
 1.22A 3ln1D-3q2eA:
undetectable		 3ln1D-3q2eA:
12.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A1337
VAL A1342
ILE A1400
MET A1403
 None
 0.40A 3u5kA-3q2eA:
16.4		 3u5kA-3q2eA:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A1337
VAL A1342
ILE A1400
MET A1403
 None
 0.47A 3u5kC-3q2eA:
16.2		 3u5kC-3q2eA:
33.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A1337
VAL A1342
ILE A1400
MET A1403
 None
 0.41A 3u5kD-3q2eA:
16.5		 3u5kD-3q2eA:
33.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A1325
LEU A1328
LEU A1407
SER A1408
 None
 0.95A 3vhuA-3q2eA:
undetectable		 3vhuA-3q2eA:
15.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 PRO A1337
VAL A1342
TYR A1350
ILE A1400
 None
 0.83A 5pbeA-3q2eA:
17.6		 5pbeA-3q2eA:
30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PHE A1411
ILE A1329
PHE A1386
PRO A1341
 None
 1.15A 5x23A-3q2eA:
undetectable		 5x23A-3q2eA:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3q2e BROMODOMAIN AND WD
REPEAT-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PRO A1337
VAL A1342
TYR A1392
ILE A1400
 None
None
ACT  A   1 ( 4.9A)
None
 0.66A 5y1yA-3q2eA:
16.4		 5y1yA-3q2eA:
30.88