SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 10 THR A 311
VAL A 130
HIS A 301
HIS A  26
MET A 101
 None
None
NAI  A 500 ( 4.9A)
None
None
 1.46A 1ivvA-3q2iA:
undetectable		 1ivvA-3q2iA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 10 THR A 311
VAL A 130
HIS A 301
HIS A  26
MET A 101
 None
None
NAI  A 500 ( 4.9A)
None
None
 1.41A 1ivvB-3q2iA:
undetectable		 1ivvB-3q2iA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		4 / 8 ALA A 120
LEU A 127
GLY A 322
GLY A 113
 None
 0.86A 1rukH-3q2iA:
undetectable
1rukL-3q2iA:
undetectable		 1rukH-3q2iA:
20.99
1rukL-3q2iA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 ASP A  67
THR A  81
PRO A  82
 None
NAI  A 500 (-4.7A)
NAI  A 500 (-4.5A)
 0.65A 2pynB-3q2iA:
undetectable		 2pynB-3q2iA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 ASP A  67
THR A  81
PRO A  82
 None
NAI  A 500 (-4.7A)
NAI  A 500 (-4.5A)
 0.66A 2q64B-3q2iA:
undetectable		 2q64B-3q2iA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 ASP A  67
THR A  81
PRO A  82
 None
NAI  A 500 (-4.7A)
NAI  A 500 (-4.5A)
 0.66A 2qakB-3q2iA:
undetectable		 2qakB-3q2iA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		4 / 8 ALA A  49
ALA A  53
THR A  57
LEU A  39
 NAI  A 500 ( 3.9A)
None
None
None
 1.02A 2wx2B-3q2iA:
undetectable		 2wx2B-3q2iA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 MET A 238
GLU A 221
ASP A 182
 None
 1.03A 3a25A-3q2iA:
5.3		 3a25A-3q2iA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 TRP A 179
VAL A 194
ARG A 134
 None
 0.74A 3b0wA-3q2iA:
undetectable		 3b0wA-3q2iA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 GLY A  18
ASP A  44
ILE A  45
ASP A  46
LEU A  85
 NAI  A 500 (-3.5A)
NAI  A 500 (-2.9A)
NAI  A 500 (-4.0A)
None
NAI  A 500 (-4.9A)
 0.58A 3cjtC-3q2iA:
6.1		 3cjtC-3q2iA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 GLY A  18
GLY A  20
ILE A  45
ASP A  46
LEU A  85
 NAI  A 500 (-3.5A)
NAI  A 500 (-3.4A)
NAI  A 500 (-4.0A)
None
NAI  A 500 (-4.9A)
 1.04A 3cjtG-3q2iA:
6.1		 3cjtG-3q2iA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 LEU A 127
GLY A 325
GLY A 322
PHE A 128
LEU A 332
 None
 1.02A 3dh0B-3q2iA:
5.0		 3dh0B-3q2iA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		4 / 8 ALA A  49
ALA A  53
THR A  57
LEU A  39
 NAI  A 500 ( 3.9A)
None
None
None
 0.90A 3khmA-3q2iA:
undetectable		 3khmA-3q2iA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.31A 4eilA-3q2iA:
2.7		 4eilA-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 10 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.30A 4eilB-3q2iA:
undetectable		 4eilB-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.30A 4eilC-3q2iA:
2.8		 4eilC-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.34A 4eilE-3q2iA:
2.2		 4eilE-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.31A 4kyaA-3q2iA:
2.8		 4kyaA-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.26A 4kyaB-3q2iA:
undetectable		 4kyaB-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 10 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.31A 4kyaC-3q2iA:
undetectable		 4kyaC-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.27A 4kyaD-3q2iA:
undetectable		 4kyaD-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.30A 4kyaE-3q2iA:
2.0		 4kyaE-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.28A 4kyaF-3q2iA:
undetectable		 4kyaF-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.28A 4kyaG-3q2iA:
2.4		 4kyaG-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 226
ALA A 339
LEU A 347
VAL A 207
THR A 211
 None
NA  A 353 ( 4.1A)
None
None
NA  A 353 (-3.6A)
 1.27A 4kyaH-3q2iA:
undetectable		 4kyaH-3q2iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 LEU A  16
ASN A  24
ILE A  22
GLY A  28
ALA A  29
 None
None
NAI  A 500 (-3.9A)
None
None
 1.11A 4nkvC-3q2iA:
undetectable		 4nkvC-3q2iA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 LEU A  16
ASN A  24
ILE A  22
GLY A  28
ALA A  29
 None
None
NAI  A 500 (-3.9A)
None
None
 1.10A 4nkvD-3q2iA:
undetectable		 4nkvD-3q2iA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 SER A  83
ASP A 182
GLN A 189
 NAI  A 500 (-2.7A)
None
HP7  A 550 (-4.8A)
 0.54A 4oltA-3q2iA:
undetectable
4oltB-3q2iA:
undetectable		 4oltA-3q2iA:
22.56
4oltB-3q2iA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 GLN A 189
SER A  83
ASP A 182
 HP7  A 550 (-4.8A)
NAI  A 500 (-2.7A)
None
 0.58A 4qwpA-3q2iA:
undetectable
4qwpB-3q2iA:
undetectable		 4qwpA-3q2iA:
21.75
4qwpB-3q2iA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		3 / 3 THR A 108
MET A 106
HIS A  86
 None
None
NAI  A 500 (-3.9A)
 0.62A 5uunA-3q2iA:
undetectable		 5uunA-3q2iA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3q2i DEHYDROGENASE
(Chromobacterium
violaceum) 		5 / 12 GLY A  18
ASP A  44
ILE A  45
ASP A  46
LEU A  85
 NAI  A 500 (-3.5A)
NAI  A 500 (-2.9A)
NAI  A 500 (-4.0A)
None
NAI  A 500 (-4.9A)
 0.96A 6bq4A-3q2iA:
4.7		 6bq4A-3q2iA:
12.98