SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A  52
ARG A  45
TRP A 143
GLY A 179
TYR A 124
 None
 1.29A 1agmA-3q2rA:
undetectable		 1agmA-3q2rA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A  52
ARG A  45
TRP A 143
GLY A 179
TYR A 124
 None
 1.29A 1agmA-3q2rA:
undetectable		 1agmA-3q2rA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ASN A  99
PRO A 106
PHE A 171
GLY A 103
SER A 104
 None
 1.50A 1g60A-3q2rA:
undetectable		 1g60A-3q2rA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ASN A  99
ILE A 107
PRO A 106
PHE A 171
GLY A 103
 None
 1.33A 1g60B-3q2rA:
undetectable		 1g60B-3q2rA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 11 VAL A 149
GLY A 150
VAL A 110
ASP A  36
ILE A  40
 None
 1.18A 1phgA-3q2rA:
undetectable		 1phgA-3q2rA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 8 ALA A  68
ILE A  67
CYH A  37
HIS A  41
PHE A 171
 None
 1.31A 1sv9A-3q2rA:
undetectable		 1sv9A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 8 ILE A  67
GLY A 150
CYH A  37
HIS A  41
PHE A 171
 None
 1.47A 1sv9A-3q2rA:
undetectable		 1sv9A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 10 ALA A  68
ILE A  67
CYH A  37
HIS A  41
PHE A 171
 None
 1.32A 2b17A-3q2rA:
undetectable		 2b17A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A  67
GLY A 150
CYH A  37
HIS A  41
PHE A 171
 None
 1.48A 2b17A-3q2rA:
undetectable		 2b17A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A  52
ARG A  45
TRP A 143
GLY A 179
TYR A 124
 None
 1.34A 2f6dA-3q2rA:
undetectable		 2f6dA-3q2rA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A  56
VAL A  38
ARG A  45
 None
 0.91A 3b0wB-3q2rA:
undetectable		 3b0wB-3q2rA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		3 / 3 PRO A  50
TYR A 186
GLY A 189
 None
 0.71A 4g2zA-3q2rA:
undetectable		 4g2zA-3q2rA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A  52
ARG A  45
TRP A 143
GLY A 179
TYR A 124
 None
 1.25A 6fhwA-3q2rA:
undetectable		 6fhwA-3q2rA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A  52
ARG A  45
TRP A 143
GLY A 179
TYR A 124
 None
 1.25A 6fhwB-3q2rA:
undetectable		 6fhwB-3q2rA:
16.99