SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3q2v CADHERIN-1
(Mus
musculus) 		3 / 3 THR A  63
PRO A  65
PRO A  18
 None
 0.79A 2d55C-3q2vA:
undetectable		 2d55C-3q2vA:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 11 HIS A 299
ASN A 263
VAL A 261
ASP A 264
PRO A 265
 MAN  A 804 ( 4.3A)
None
None
None
None
 1.15A 2zwfA-3q2vA:
undetectable
2zwfB-3q2vA:
undetectable		 2zwfA-3q2vA:
19.53
2zwfB-3q2vA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 11 HIS A 299
ASN A 263
VAL A 261
ASP A 264
PRO A 265
 MAN  A 804 ( 4.3A)
None
None
None
None
 1.13A 2zwgA-3q2vA:
undetectable
2zwgB-3q2vA:
undetectable		 2zwgA-3q2vA:
19.53
2zwgB-3q2vA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3q2v CADHERIN-1
(Mus
musculus) 		4 / 5 THR A 368
ILE A 367
GLU A 358
PHE A 332
 None
None
CA  A 609 (-2.9A)
None
 1.45A 4acbC-3q2vA:
undetectable		 4acbC-3q2vA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3q2v CADHERIN-1
(Mus
musculus) 		3 / 3 ASN A 435
ASP A 517
ASN A 518
 CA  A 612 (-2.8A)
CA  A 612 (-3.2A)
None
 0.64A 4agaA-3q2vA:
undetectable		 4agaA-3q2vA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3q2v CADHERIN-1
(Mus
musculus) 		4 / 8 ASP A 325
ASP A 415
ASP A 360
GLU A 291
 CA  A 607 (-3.2A)
CA  A 609 (-3.0A)
CA  A 609 ( 3.4A)
CA  A 607 ( 2.7A)
 1.07A 4feuD-3q2vA:
undetectable		 4feuD-3q2vA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3q2v CADHERIN-1
(Mus
musculus) 		3 / 3 ASN A 520
ASP A 464
ASP A 344
 None
CA  A 611 ( 3.5A)
None
 0.79A 4obwD-3q2vA:
undetectable		 4obwD-3q2vA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 12 ILE A 511
VAL A 529
VAL A 531
PHE A 448
MET A 446
 None
 1.03A 4y0qA-3q2vA:
undetectable		 4y0qA-3q2vA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 11 HIS A 299
ASN A 263
VAL A 261
ASP A 264
PRO A 265
 MAN  A 804 ( 4.3A)
None
None
None
None
 1.12A 5z0hA-3q2vA:
undetectable
5z0hB-3q2vA:
undetectable		 5z0hA-3q2vA:
9.70
5z0hB-3q2vA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 11 HIS A 299
ASN A 263
VAL A 261
ASP A 264
PRO A 265
 MAN  A 804 ( 4.3A)
None
None
None
None
 1.15A 5z0lA-3q2vA:
undetectable
5z0lB-3q2vA:
undetectable		 5z0lA-3q2vA:
9.70
5z0lB-3q2vA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3q2v CADHERIN-1
(Mus
musculus) 		5 / 11 HIS A 299
ASN A 263
VAL A 261
ASP A 264
PRO A 265
 MAN  A 804 ( 4.3A)
None
None
None
None
 1.11A 5z0mA-3q2vA:
undetectable
5z0mB-3q2vA:
undetectable		 5z0mA-3q2vA:
9.70
5z0mB-3q2vA:
10.02