SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA501_1 (SALICYLIC ACID-BINDING PROTEIN 2)	3q2w	CADHERIN-2 (Mus musculus)	5 / 9	GLY A 40 ALA A 43 LEU A 76 LEU A 60 HIS A 79	None	1.36A	1y7iA-3q2wA: undetectable	1y7iA-3q2wA: 18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L2V_A_RLTA397_1 (INTEGRASE)	3q2w	CADHERIN-2 (Mus musculus)	4 / 7	ASP A 218 ASP A 250 GLN A 184 GLU A 119	CA A 604 ( 2.7A) CA A 605 ( 3.3A) None CA A 604 ( 2.7A)	1.06A	3l2vA-3q2wA: undetectable	3l2vA-3q2wA: 23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3O_A_DLUA399_1 (PFV INTEGRASE)	3q2w	CADHERIN-2 (Mus musculus)	4 / 7	ASP A 218 ASP A 250 GLN A 184 GLU A 119	CA A 604 ( 2.7A) CA A 605 ( 3.3A) None CA A 604 ( 2.7A)	1.29A	3s3oA-3q2wA: undetectable	3s3oA-3q2wA: 23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB501_1 (HEMOLYTIC LECTIN CEL-III)	3q2w	CADHERIN-2 (Mus musculus)	4 / 5	ASP A 420 SER A 427 GLY A 428 ASP A 364	CA A 609 (-3.1A) MAN A 708 (-1.4A) MAN A 709 ( 4.9A) CA A 609 (-2.6A)	1.06A	3w9tB-3q2wA: undetectable	3w9tB-3q2wA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_B_H4BB600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3q2w	CADHERIN-2 (Mus musculus)	4 / 8	HIS A 79 GLU A 89 ARG A 77 ILE A 4	None	1.10A	4cx7A-3q2wA: undetectable 4cx7B-3q2wA: undetectable	4cx7A-3q2wA: 21.32 4cx7B-3q2wA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q5M_A_ROCA1101_3 (PROTEASE)	3q2w	CADHERIN-2 (Mus musculus)	3 / 3	ASP A 331 ASP A 366 ASN A 335	CA A 608 (-3.2A) CA A 608 ( 3.4A) None	0.75A	4q5mA-3q2wA: undetectable	4q5mA-3q2wA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R3A_B_RBFB402_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	3q2w	CADHERIN-2 (Mus musculus)	5 / 12	LEU A 66 ILE A 52 ILE A 94 LEU A 76 GLY A 42	None	0.98A	4r3aB-3q2wA: undetectable	4r3aB-3q2wA: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D9K_F_ACTF802_0 (UNCHARACTERIZED PROTEIN)	3q2w	CADHERIN-2 (Mus musculus)	3 / 3	TYR A 186 ALA A 175 LEU A 178	None	0.73A	6d9kF-3q2wA: undetectable	6d9kF-3q2wA: 22.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_A_SALA501_1","SALICYLIC ACID-BINDING PROTEIN 2","3q2w","CADHERIN-2","Mus musculus",5,"GLY A  40;ALA A  43;LEU A  76;LEU A  60;HIS A  79","None","1.36A","1y7iA-3q2wA:undetectable","1y7iA-3q2wA:18.02"],["3L2V_A_RLTA397_1","INTEGRASE","3q2w","CADHERIN-2","Mus musculus",4,"ASP A 218;ASP A 250;GLN A 184;GLU A 119"," CA A 604 ( 2.7A); CA A 605 ( 3.3A);None; CA A 604 ( 2.7A)","1.06A","3l2vA-3q2wA:undetectable","3l2vA-3q2wA:23.93"],["3S3O_A_DLUA399_1","PFV INTEGRASE","3q2w","CADHERIN-2","Mus musculus",4,"ASP A 218;ASP A 250;GLN A 184;GLU A 119"," CA A 604 ( 2.7A); CA A 605 ( 3.3A);None; CA A 604 ( 2.7A)","1.29A","3s3oA-3q2wA:undetectable","3s3oA-3q2wA:23.93"],["3W9T_B_W9TB501_1","HEMOLYTIC LECTIN CEL-III","3q2w","CADHERIN-2","Mus musculus",4,"ASP A 420;SER A 427;GLY A 428;ASP A 364"," CA A 609 (-3.1A);MAN A 708 (-1.4A);MAN A 709 ( 4.9A); CA A 609 (-2.6A)","1.06A","3w9tB-3q2wA:undetectable","3w9tB-3q2wA:20.69"],["4CX7_B_H4BB600_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3q2w","CADHERIN-2","Mus musculus",4,"HIS A  79;GLU A  89;ARG A  77;ILE A   4","None","1.10A","4cx7A-3q2wA:undetectable;4cx7B-3q2wA:undetectable","4cx7A-3q2wA:21.32;4cx7B-3q2wA:21.32"],["4Q5M_A_ROCA1101_3","PROTEASE","3q2w","CADHERIN-2","Mus musculus",3,"ASP A 331;ASP A 366;ASN A 335"," CA A 608 (-3.2A); CA A 608 ( 3.4A);None","0.75A","4q5mA-3q2wA:undetectable","4q5mA-3q2wA:18.95"],["4R3A_B_RBFB402_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","3q2w","CADHERIN-2","Mus musculus",5,"LEU A  66;ILE A  52;ILE A  94;LEU A  76;GLY A  42","None","0.98A","4r3aB-3q2wA:undetectable","4r3aB-3q2wA:21.17"],["6D9K_F_ACTF802_0","UNCHARACTERIZED PROTEIN","3q2w","CADHERIN-2","Mus musculus",3,"TYR A 186;ALA A 175;LEU A 178","None","0.73A","6d9kF-3q2wA:undetectable","6d9kF-3q2wA:22.44"]]