SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		3 / 3 THR A 372
GLU A 378
ASP A 385
 None
 0.84A 1nt2A-3q33A:
2.1		 1nt2A-3q33A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		5 / 12 ASN A  36
ILE A 185
ASP A  78
ARG A  41
ALA A  31
 None
 1.12A 2qmjA-3q33A:
undetectable		 2qmjA-3q33A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.11A 2y69C-3q33A:
undetectable
2y69J-3q33A:
undetectable		 2y69C-3q33A:
19.95
2y69J-3q33A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.18A 2y69P-3q33A:
undetectable
2y69W-3q33A:
undetectable		 2y69P-3q33A:
19.95
2y69W-3q33A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.10A 3abmC-3q33A:
undetectable
3abmJ-3q33A:
undetectable		 3abmC-3q33A:
19.95
3abmJ-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.05A 3abmP-3q33A:
undetectable
3abmW-3q33A:
undetectable		 3abmP-3q33A:
19.95
3abmW-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.13A 3ag3C-3q33A:
undetectable
3ag3J-3q33A:
undetectable		 3ag3C-3q33A:
19.95
3ag3J-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  20
SER A  54
PHE A  56
ALA A 379
 None
 0.99A 3ax9A-3q33A:
undetectable		 3ax9A-3q33A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 111
LEU A  65
THR A 187
VAL A  85
 None
None
None
ACO  A 501 (-4.9A)
 0.79A 3dcjB-3q33A:
undetectable		 3dcjB-3q33A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 228
ARG A 101
ILE A 231
 None
ACO  A 501 (-3.4A)
None
 0.84A 4b7qC-3q33A:
undetectable		 4b7qC-3q33A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 8 SER A  54
ILE A 365
LEU A 387
ILE A 361
 None
 0.74A 4dtaB-3q33A:
undetectable		 4dtaB-3q33A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 6 PHE A  53
HIS A  51
ILE A 111
TYR A 119
 None
 1.48A 4o7gB-3q33A:
undetectable		 4o7gB-3q33A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 7 GLN A  23
PRO A 352
THR A  49
ILE A  47
 None
 0.97A 4pcuA-3q33A:
undetectable		 4pcuA-3q33A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 301
THR A  34
PRO A  35
VAL A 279
 None
 1.11A 4yoaA-3q33A:
undetectable		 4yoaA-3q33A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		5 / 11 PRO A 344
ILE A 107
VAL A 349
PHE A  53
LEU A 398
 None
 1.43A 5tiyA-3q33A:
undetectable		 5tiyA-3q33A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 8 ARG A  81
VAL A  67
PHE A  53
THR A  49
 None
 0.91A 5v0vA-3q33A:
undetectable		 5v0vA-3q33A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.13A 5wauc-3q33A:
undetectable
5wauj-3q33A:
undetectable		 5wauc-3q33A:
19.95
5wauj-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.14A 5xdqC-3q33A:
undetectable
5xdqJ-3q33A:
undetectable		 5xdqC-3q33A:
19.95
5xdqJ-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 218
ARG A 243
MET A 330
LEU A 191
 ACO  A 501 (-4.6A)
None
None
ACO  A 501 ( 4.0A)
 0.98A 5xdqA-3q33A:
undetectable
5xdqJ-3q33A:
undetectable		 5xdqA-3q33A:
22.18
5xdqJ-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.12A 5xdqP-3q33A:
undetectable
5xdqW-3q33A:
undetectable		 5xdqP-3q33A:
19.95
5xdqW-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.11A 5zcoP-3q33A:
undetectable
5zcoW-3q33A:
undetectable		 5zcoP-3q33A:
19.95
5zcoW-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 318
PHE A 311
LEU A 315
PHE A 321
 None
 1.11A 5zcpC-3q33A:
undetectable
5zcpJ-3q33A:
undetectable		 5zcpC-3q33A:
19.95
5zcpJ-3q33A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 357
THR A  49
HIS A  51
LEU A  22
 None
 1.39A 6gbnB-3q33A:
undetectable		 6gbnB-3q33A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q33 HISTONE
ACETYLTRANSFERASE
RTT109
(Saccharomyces
cerevisiae) 		4 / 6 LYS A  60
GLN A  58
LEU A  55
PHE A  63
 None
 1.31A 6nmpC-3q33A:
undetectable
6nmpJ-3q33A:
undetectable		 6nmpC-3q33A:
19.95
6nmpJ-3q33A:
8.47