SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		4 / 7 VAL B 121
ILE B  83
ARG B 184
LEU B 203
 None
 0.89A 1iepB-3q35B:
undetectable		 1iepB-3q35B:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		3 / 3 PHE B 116
PHE B 180
PHE B 183
 None
 0.83A 2od9A-3q35B:
undetectable		 2od9A-3q35B:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		3 / 3 PHE B 116
PHE B 180
PHE B 183
 None
 0.83A 2qqgA-3q35B:
undetectable		 2qqgA-3q35B:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		4 / 8 PHE B 125
ILE B 105
TRP B 185
ILE B  83
 None
 0.94A 2qwxA-3q35B:
undetectable
2qwxB-3q35B:
undetectable		 2qwxA-3q35B:
23.68
2qwxB-3q35B:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		4 / 7 LEU B  91
GLU B  94
SER B 104
THR B 122
 None
 1.20A 3dzgB-3q35B:
undetectable		 3dzgB-3q35B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		4 / 5 PHE B 204
THR B 122
PHE B 125
ILE B  86
 None
 1.21A 4jx1E-3q35B:
undetectable		 4jx1E-3q35B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3q35 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 75
(Saccharomyces
cerevisiae) 		4 / 7 ASP B  99
ASP B 102
ARG B  30
LYS B 129
 None
 1.27A 6g31A-3q35B:
undetectable		 6g31A-3q35B:
15.02