SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q3h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ALA A  24
LEU A  29
ILE A 143
LEU A  98
ILE A  72
None
1.07A 1draB-3q3hA:
undetectable
1draB-3q3hA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 9 PHE A 609
ILE A 341
ASP A 313
LEU A 296
PHE A 294
None
1.43A 1i00A-3q3hA:
undetectable
1i00A-3q3hA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 9 PHE A 609
ILE A 341
ASP A 313
LEU A 296
PHE A 294
None
1.39A 1i00B-3q3hA:
undetectable
1i00B-3q3hA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 LEU A 549
ASP A 388
SER A 286
THR A 520
GLY A 370
None
None
None
UDP  A 621 (-3.7A)
None
1.31A 1ia0B-3q3hA:
undetectable
1ia0B-3q3hA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 11 LEU A 202
LEU A 235
VAL A 238
LEU A 205
HIS A 219
None
1.40A 1kt6A-3q3hA:
undetectable
1kt6A-3q3hA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 11 LEU A 202
LEU A 235
VAL A 238
LEU A 205
HIS A 219
None
1.40A 1kt7A-3q3hA:
undetectable
1kt7A-3q3hA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 ALA A  99
TYR A 477
ILE A 179
PRO A 176
None
1.21A 1oniH-3q3hA:
undetectable
1oniI-3q3hA:
undetectable
1oniH-3q3hA:
12.28
1oniI-3q3hA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ALA A 211
MET A 351
PHE A 171
LEU A 199
PRO A 196
None
1.02A 1rx8A-3q3hA:
undetectable
1rx8A-3q3hA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 LEU A 549
ASP A 388
SER A 286
THR A 520
GLY A 370
None
None
None
UDP  A 621 (-3.7A)
None
1.31A 1tubB-3q3hA:
undetectable
1tubB-3q3hA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 4 GLN A  89
GLU A 164
ILE A 208
PRO A 209
None
1.08A 2fcnA-3q3hA:
undetectable
2fcnA-3q3hA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 7 GLY A 518
TYR A 222
ASP A 546
ASP A 388
None
1.09A 2g72B-3q3hA:
undetectable
2g72B-3q3hA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 10 PHE A 609
ILE A 341
ASP A 313
LEU A 296
PHE A 294
None
1.37A 2tsrC-3q3hA:
undetectable
2tsrC-3q3hA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 10 ILE A  72
LEU A  29
SER A  84
ILE A  83
PHE A  76
None
1.15A 2w9sC-3q3hA:
undetectable
2w9sC-3q3hA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 7 THR A 116
TYR A 117
ILE A 129
SER A  77
None
1.17A 2xytI-3q3hA:
undetectable
2xytI-3q3hA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 PHE A 273
VAL A 311
PHE A 609
LEU A 403
TYR A 343
None
1.25A 3apxA-3q3hA:
undetectable
3apxA-3q3hA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
3 / 3 MET A 323
VAL A 318
GLU A 328
None
0.82A 3c6gA-3q3hA:
undetectable
3c6gA-3q3hA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 10 MET A 287
GLU A 314
LEU A 299
ARG A 260
LEU A 270
None
1.39A 3erdB-3q3hA:
undetectable
3erdB-3q3hA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 LEU A 146
ILE A  72
LEU A  28
PHE A  76
TYR A 117
None
1.08A 3fl9B-3q3hA:
undetectable
3fl9B-3q3hA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 9 LEU A 146
ILE A  72
LEU A  28
PHE A  76
TYR A 117
None
1.01A 3fl9D-3q3hA:
undetectable
3fl9D-3q3hA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 LEU A 146
ILE A  72
LEU A  28
PHE A  76
TYR A 117
None
1.04A 3fl9G-3q3hA:
undetectable
3fl9G-3q3hA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 GLY A  41
GLN A  43
TRP A  97
THR A 439
VAL A 478
None
1.48A 3gn8A-3q3hA:
undetectable
3gn8A-3q3hA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 GLY A  41
GLN A  43
TRP A  97
THR A 439
VAL A 478
None
1.49A 3gn8B-3q3hA:
undetectable
3gn8B-3q3hA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 TYR A 567
ASN A 519
ASP A 546
LYS A 536
None
UDP  A 621 ( 4.9A)
None
None
1.26A 3lslG-3q3hA:
undetectable
3lslG-3q3hA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 THR A 116
TYR A 117
ILE A 129
SER A  77
None
1.23A 3peoG-3q3hA:
undetectable
3peoG-3q3hA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 LEU A  98
TYR A  94
ALA A 172
LEU A  32
None
0.98A 3ravA-3q3hA:
undetectable
3ravA-3q3hA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 LEU A  98
TYR A  94
ALA A 172
LEU A  32
None
0.97A 3rd0A-3q3hA:
undetectable
3rd0A-3q3hA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 9 PHE A 609
ILE A 341
ASP A 313
LEU A 296
PHE A 294
None
1.39A 4eb4C-3q3hA:
undetectable
4eb4C-3q3hA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 GLU A 580
ASN A 577
VAL A 461
ILE A 433
LEU A 450
None
1.39A 4k36A-3q3hA:
2.5
4k36A-3q3hA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 GLU A 580
ASN A 577
VAL A 461
ILE A 433
LEU A 450
None
1.39A 4k36B-3q3hA:
2.2
4k36B-3q3hA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 11 GLU A 580
ASN A 577
VAL A 461
ILE A 433
LEU A 450
None
1.41A 4k37B-3q3hA:
2.2
4k37B-3q3hA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 GLU A 580
ASN A 577
VAL A 461
ILE A 433
LEU A 450
None
1.40A 4k39A-3q3hA:
2.5
4k39A-3q3hA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ALA A  24
LEU A  29
ILE A 143
LEU A  98
ILE A  72
None
1.14A 4nx6A-3q3hA:
2.6
4nx6A-3q3hA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ALA A  24
LEU A  29
ILE A 143
LEU A  98
ILE A  72
None
1.10A 4nx7A-3q3hA:
2.2
4nx7A-3q3hA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ILE A 504
ILE A 588
LEU A 553
GLY A 533
ASN A 513
None
1.07A 4o1eB-3q3hA:
undetectable
4o1eB-3q3hA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 ASP A 350
GLY A 300
VAL A 304
HIS A 272
None
1.00A 4oltA-3q3hA:
undetectable
4oltA-3q3hA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 ASP A 350
GLY A 300
VAL A 304
HIS A 272
None
0.98A 4oltB-3q3hA:
undetectable
4oltB-3q3hA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 8 TYR A 222
PHE A 517
GLY A 370
ILE A 367
None
0.89A 4qoiA-3q3hA:
5.5
4qoiB-3q3hA:
3.2
4qoiA-3q3hA:
16.80
4qoiB-3q3hA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 PHE A  12
MET A  68
ILE A 101
LEU A  98
LEU A  75
None
1.39A 4qynB-3q3hA:
undetectable
4qynB-3q3hA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 ALA A 211
ILE A 212
ILE A 239
ASN A 236
LEU A 235
None
1.09A 4r3aA-3q3hA:
undetectable
4r3aA-3q3hA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 VAL A  16
LEU A  98
ILE A  72
ILE A 113
LEU A  29
None
1.18A 4y0pA-3q3hA:
undetectable
4y0pA-3q3hA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 9 VAL A  16
PHE A  12
ILE A  72
PHE A  76
LEU A  81
None
1.46A 5e4dA-3q3hA:
undetectable
5e4dA-3q3hA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 ILE A 297
PHE A 315
PHE A 342
THR A 353
None
1.18A 5g08A-3q3hA:
undetectable
5g08A-3q3hA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 PHE A  64
LEU A  32
LEU A  28
PHE A 102
LEU A 144
None
1.19A 5iepA-3q3hA:
undetectable
5iepA-3q3hA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 PHE A 446
THR A 224
PHE A 465
ALA A 490
GLU A 448
None
1.18A 5vcgA-3q3hA:
undetectable
5vcgA-3q3hA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
5 / 12 SER A 286
THR A 285
ILE A 288
PHE A 273
TYR A 343
None
1.15A 6a93A-3q3hA:
undetectable
6a93A-3q3hA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)
3q3h HMW1C-LIKE
GLYCOSYLTRANSFERASE

(Actinobacillus
pleuropneumoniae)
4 / 6 ILE A 433
LEU A 486
VAL A 461
ARG A 454
None
1.29A 6f6jA-3q3hA:
undetectable
6f6jA-3q3hA:
undetectable