SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 5 THR A  89
ASP A 300
HIS A 304
HIS A 346
HIS A 491
 ZN  A1559 ( 2.6A)
ZN  A1561 ( 2.1A)
ZN  A1561 ( 3.2A)
ZN  A1559 ( 3.2A)
ZN  A1561 ( 3.2A)
 0.47A 1ei6A-3q3qA:
25.6		 1ei6A-3q3qA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		6 / 8 ASP A  49
THR A  89
ASP A 300
HIS A 304
HIS A 346
HIS A 491
 ZN  A1559 (-2.3A)
ZN  A1559 ( 2.6A)
ZN  A1561 ( 2.1A)
ZN  A1561 ( 3.2A)
ZN  A1559 ( 3.2A)
ZN  A1561 ( 3.2A)
 0.45A 1ei6C-3q3qA:
25.6		 1ei6C-3q3qA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 8 THR A  89
ASP A 300
HIS A 304
HIS A 491
 ZN  A1559 ( 2.6A)
ZN  A1561 ( 2.1A)
ZN  A1561 ( 3.2A)
ZN  A1561 ( 3.2A)
 0.44A 1ei6D-3q3qA:
25.3		 1ei6D-3q3qA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.04A 1jhoA-3q3qA:
2.1		 1jhoA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.05A 1jhrA-3q3qA:
undetectable		 1jhrA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.08A 1jhyA-3q3qA:
2.3		 1jhyA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 VAL A 501
ALA A 298
SER A 297
GLY A 348
HIS A 304
 None
None
None
None
ZN  A1561 ( 3.2A)
 0.99A 1kiaA-3q3qA:
undetectable		 1kiaA-3q3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.07A 1l4nA-3q3qA:
1.9		 1l4nA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.05A 1l5kA-3q3qA:
1.5		 1l5kA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.02A 1l5lA-3q3qA:
2.0		 1l5lA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 GLY A 246
GLY A 303
PHE A 306
SER A 313
GLU A 312
 None
 1.03A 1l5mA-3q3qA:
2.0		 1l5mA-3q3qA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 10 GLY A 310
ARG A 356
GLU A 353
LEU A 351
PRO A 352
 None
 1.48A 1mjqG-3q3qA:
undetectable
1mjqH-3q3qA:
undetectable		 1mjqG-3q3qA:
11.03
1mjqH-3q3qA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 VAL A 501
ALA A 298
SER A 297
GLY A 348
HIS A 304
 None
None
None
None
ZN  A1561 ( 3.2A)
 1.02A 1nbhB-3q3qA:
undetectable		 1nbhB-3q3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 VAL A 501
ALA A 298
SER A 297
GLY A 348
HIS A 304
 None
None
None
None
ZN  A1561 ( 3.2A)
 1.07A 1nbiA-3q3qA:
undetectable		 1nbiA-3q3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 VAL A 501
ALA A 298
SER A 297
GLY A 348
HIS A 304
 None
None
None
None
ZN  A1561 ( 3.2A)
 1.07A 1nbiB-3q3qA:
undetectable		 1nbiB-3q3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 ASP A 399
LEU A 469
HIS A 346
 None
GOL  A8002 ( 4.8A)
ZN  A1559 ( 3.2A)
 0.59A 1qknA-3q3qA:
undetectable		 1qknA-3q3qA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 10 ALA A 240
LEU A 351
GLY A 307
PHE A 306
GLY A 246
 None
 1.49A 1ruaH-3q3qA:
undetectable
1ruaL-3q3qA:
undetectable		 1ruaH-3q3qA:
17.55
1ruaL-3q3qA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 7 THR A  71
LEU A 504
VAL A 317
ASP A 321
 None
 1.06A 1t85A-3q3qA:
undetectable		 1t85A-3q3qA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 7 THR A  71
LEU A 504
VAL A 317
ASP A 321
 None
 1.06A 1t87A-3q3qA:
undetectable		 1t87A-3q3qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_B_NCAB508_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 GLN A 266
LEU A 189
TYR A 257
TYR A 301
 None
 1.45A 1yc2B-3q3qA:
2.4
1yc2C-3q3qA:
undetectable		 1yc2B-3q3qA:
18.41
1yc2C-3q3qA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 GLN A  82
HIS A  84
ARG A 101
 None
 0.91A 1zlqA-3q3qA:
undetectable		 1zlqA-3q3qA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 ILE A 336
PHE A 327
PHE A 328
ILE A 292
 None
 0.90A 2hjhA-3q3qA:
undetectable		 2hjhA-3q3qA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 ARG A 243
THR A 247
VAL A 245
 None
 0.95A 2q64A-3q3qA:
undetectable		 2q64A-3q3qA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 10 THR A 343
VAL A 341
SER A 527
VAL A 519
GLY A  80
 None
 1.47A 2x2iD-3q3qA:
undetectable		 2x2iD-3q3qA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 GLY A 492
ALA A  86
VAL A 476
PRO A 396
VAL A 366
 GOL  A8002 (-4.8A)
GOL  A8002 (-3.9A)
None
None
None
 1.10A 2zulA-3q3qA:
undetectable		 2zulA-3q3qA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 9 ALA A 274
PHE A 327
SER A 167
LEU A  97
ILE A 291
 None
 1.19A 3claA-3q3qA:
undetectable		 3claA-3q3qA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 GLY A 492
ALA A  86
VAL A 476
PRO A 396
VAL A 366
 GOL  A8002 (-4.8A)
GOL  A8002 (-3.9A)
None
None
None
 1.06A 3dmfA-3q3qA:
undetectable		 3dmfA-3q3qA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 GLY A 492
ALA A  86
VAL A 476
PRO A 396
VAL A 366
 GOL  A8002 (-4.8A)
GOL  A8002 (-3.9A)
None
None
None
 1.08A 3dmhA-3q3qA:
undetectable		 3dmhA-3q3qA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 ASN A 280
ASP A 290
GLN A 288
 None
 0.66A 3eeyC-3q3qA:
2.0		 3eeyC-3q3qA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 ASN A 280
ASP A 290
GLN A 288
 None
 0.68A 3eeyD-3q3qA:
undetectable		 3eeyD-3q3qA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 ASN A 280
ASP A 290
GLN A 288
 None
 0.65A 3eeyE-3q3qA:
undetectable		 3eeyE-3q3qA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 8 VAL A 488
VAL A 238
ILE A 262
GLY A 307
 None
 0.95A 3hjoA-3q3qA:
undetectable		 3hjoA-3q3qA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 ALA A 169
MET A 177
ILE A 176
SER A 197
GLY A  92
 None
 1.26A 3lbdA-3q3qA:
undetectable		 3lbdA-3q3qA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_B_ACTB600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 ARG A 499
HIS A  84
ALA A 458
GLU A 520
 None
 1.46A 3mbgB-3q3qA:
0.0
3mbgC-3q3qA:
0.0		 3mbgB-3q3qA:
12.75
3mbgC-3q3qA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 GLU A 520
ARG A 499
HIS A  84
ALA A 458
 None
 1.45A 3mbgB-3q3qA:
undetectable
3mbgC-3q3qA:
undetectable		 3mbgB-3q3qA:
12.75
3mbgC-3q3qA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 7 ASP A 332
VAL A  44
ILE A 292
TYR A 338
 None
 1.00A 3pglA-3q3qA:
undetectable		 3pglA-3q3qA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 7 ASP A 332
VAL A  44
ILE A 294
TYR A 338
 None
 1.01A 3pglA-3q3qA:
undetectable		 3pglA-3q3qA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 7 THR A  89
ASP A 300
HIS A 304
HIS A 491
 ZN  A1559 ( 2.6A)
ZN  A1561 ( 2.1A)
ZN  A1561 ( 3.2A)
ZN  A1561 ( 3.2A)
 0.40A 3t01A-3q3qA:
25.3		 3t01A-3q3qA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 PHE A 260
GLY A 259
PRO A 192
GLY A 190
ASN A 211
 None
 1.06A 3v3oB-3q3qA:
undetectable		 3v3oB-3q3qA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 11 PHE A 260
GLY A 259
PRO A 192
GLY A 190
ASN A 211
 None
 1.19A 4a6nA-3q3qA:
undetectable		 4a6nA-3q3qA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ABZ_A_T1CA1209_1
(TETRACYCLINE
REPRESSOR CLASS D)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 HIS A  93
SER A  47
ARG A 101
GLN A  82
THR A 343
 None
 1.48A 4abzA-3q3qA:
1.1		 4abzA-3q3qA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 8 SER A 131
GLN A 132
ILE A 176
VAL A 186
 None
 0.87A 4dx7B-3q3qA:
2.2		 4dx7B-3q3qA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 11 ILE A 379
THR A 378
ALA A 369
LEU A 375
THR A 371
 None
 1.15A 4g1bB-3q3qA:
undetectable		 4g1bB-3q3qA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 THR A 311
GLY A 246
VAL A 238
PRO A 237
 None
 0.96A 4grkA-3q3qA:
0.8		 4grkA-3q3qA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 LEU A 525
ALA A 159
ILE A  43
GLY A 153
GLY A 179
 None
 1.04A 4hfpB-3q3qA:
undetectable		 4hfpB-3q3qA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		3 / 3 LEU A 227
PRO A 228
ARG A 354
 None
 0.18A 4klrB-3q3qA:
undetectable		 4klrB-3q3qA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 4 THR A 490
GLY A 395
ASP A 394
SER A 478
 None
 1.30A 4rfqA-3q3qA:
undetectable		 4rfqA-3q3qA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 10 GLY A 284
ASP A 334
ALA A 275
ILE A 292
LEU A  42
 None
 1.21A 4xj7A-3q3qA:
undetectable
4xj7B-3q3qA:
undetectable		 4xj7A-3q3qA:
20.36
4xj7B-3q3qA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 6 ARG A 252
GLN A 266
PHE A 214
LEU A 218
 None
 1.16A 5b1bC-3q3qA:
undetectable
5b1bJ-3q3qA:
undetectable		 5b1bC-3q3qA:
18.10
5b1bJ-3q3qA:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 PHE A  51
HIS A  93
LEU A 296
PRO A 502
 None
 1.29A 5csyB-3q3qA:
undetectable		 5csyB-3q3qA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 ILE A  35
ILE A  96
PHE A 505
ILE A 503
PHE A 513
 None
 0.87A 5mueA-3q3qA:
undetectable		 5mueA-3q3qA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 ILE A 292
LEU A  67
ILE A 503
PHE A  56
ILE A  96
 None
 0.86A 5mugA-3q3qA:
undetectable		 5mugA-3q3qA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		4 / 5 HIS A  93
ALA A 344
SER A  47
GLY A 295
 None
 1.10A 5yodB-3q3qA:
undetectable		 5yodB-3q3qA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3q3q ALKALINE PHOSPHATASE
(Sphingomonas
sp.
BSAR-1) 		5 / 12 VAL A 501
ILE A 503
SER A  94
VAL A 522
ILE A 524
 None
 1.43A 6gsdA-3q3qA:
undetectable		 6gsdA-3q3qA:
10.64