SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 ALA A 366
ASP A 365
VAL A 351
THR A 374
ILE A 372
 None
 1.01A 1c6zB-3q3vA:
undetectable		 1c6zB-3q3vA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A 353
GLY A 321
GLY A 375
ALA A 357
VAL A 360
 None
 1.21A 1jg2A-3q3vA:
4.3		 1jg2A-3q3vA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 LEU A  12
GLY A 172
TYR A  48
ASP A 180
ALA A 171
 None
 1.12A 2br4C-3q3vA:
undetectable		 2br4C-3q3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 LEU A  12
GLY A 172
TYR A  48
ASP A 180
ALA A 171
 None
 1.14A 2br4E-3q3vA:
undetectable		 2br4E-3q3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 LEU A  12
GLY A 172
TYR A  48
ASP A 180
ALA A 171
 None
 1.14A 2br4F-3q3vA:
undetectable		 2br4F-3q3vA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		3 / 3 ASN A 320
ILE A 317
MET A 369
 None
 0.85A 2h42C-3q3vA:
undetectable		 2h42C-3q3vA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A 170
ALA A 171
ILE A 179
GLY A 390
ILE A   4
 None
 0.90A 2hs1A-3q3vA:
undetectable		 2hs1A-3q3vA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		3 / 3 ASP A  35
ARG A  38
ARG A  37
 None
 1.09A 2j9dA-3q3vA:
undetectable
2j9dC-3q3vA:
undetectable		 2j9dA-3q3vA:
16.17
2j9dC-3q3vA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 5 VAL A 359
THR A 356
GLY A 198
TRP A 319
 None
 0.98A 2p2fA-3q3vA:
2.9		 2p2fA-3q3vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 5 VAL A 359
THR A 356
GLY A 199
TRP A 319
 None
 1.15A 2p2fA-3q3vA:
2.9		 2p2fA-3q3vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 5 VAL A 359
VAL A 351
GLY A 352
TRP A 319
 None
 0.82A 2p2fA-3q3vA:
2.9		 2p2fA-3q3vA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 8 GLY A 321
GLY A 198
GLY A 222
SER A 335
 None
None
FMT  A 403 ( 4.3A)
None
 0.70A 3d41A-3q3vA:
3.9		 3d41A-3q3vA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		3 / 3 ASN A 127
HIS A 154
VAL A 149
 None
None
SO4  A 404 (-4.3A)
 0.89A 3elzB-3q3vA:
undetectable		 3elzB-3q3vA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 PRO A 322
GLY A 352
ASN A 320
ILE A 372
ARG A 362
 None
 1.48A 4kotA-3q3vA:
undetectable		 4kotA-3q3vA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 PRO A 322
GLY A 352
ASN A 320
ILE A 372
ARG A 362
 None
 1.48A 4kovA-3q3vA:
undetectable		 4kovA-3q3vA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 11 PRO A 322
GLY A 352
ASN A 320
ILE A 372
ARG A 362
 None
 1.47A 4koyA-3q3vA:
undetectable		 4koyA-3q3vA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 ALA A 366
ASP A 365
VAL A 351
THR A 374
ILE A 372
 None
 1.01A 4njvA-3q3vA:
undetectable		 4njvA-3q3vA:
14.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		9 / 12 GLY A 199
GLY A 223
GLY A 224
PHE A 227
LEU A 241
MET A 295
LEU A 297
GLY A 324
VAL A 325
 None
FMT  A 403 (-3.9A)
FMT  A 403 ( 4.8A)
FMT  A 403 (-4.4A)
None
None
None
FMT  A 403 ( 3.8A)
None
 0.49A 4o33A-3q3vA:
52.8		 4o33A-3q3vA:
46.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		8 / 12 GLY A 199
GLY A 223
GLY A 224
PHE A 227
LEU A 241
MET A 295
LEU A 297
GLY A 324
 None
FMT  A 403 (-3.9A)
FMT  A 403 ( 4.8A)
FMT  A 403 (-4.4A)
None
None
None
FMT  A 403 ( 3.8A)
 0.47A 4o3fA-3q3vA:
51.0		 4o3fA-3q3vA:
45.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		8 / 12 GLY A 199
GLY A 223
GLY A 224
PHE A 227
MET A 295
LEU A 297
GLY A 324
VAL A 325
 None
FMT  A 403 (-3.9A)
FMT  A 403 ( 4.8A)
FMT  A 403 (-4.4A)
None
None
FMT  A 403 ( 3.8A)
None
 0.42A 4o3fA-3q3vA:
51.0		 4o3fA-3q3vA:
45.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 11 PHE A 173
ASP A 145
ILE A 143
ASN A 144
TYR A  48
 None
 1.01A 4rtrA-3q3vA:
3.6		 4rtrA-3q3vA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 PHE A 173
ASP A 145
ILE A 143
ASN A 144
TYR A  48
 None
 0.98A 4rtsA-3q3vA:
3.5		 4rtsA-3q3vA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 4 LEU A 388
VAL A 391
GLU A 387
ARG A 395
 None
 0.88A 4ww7A-3q3vA:
undetectable		 4ww7A-3q3vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		4 / 7 THR A  45
ASP A 145
GLY A 170
TYR A 142
 None
 1.07A 5hwaA-3q3vA:
undetectable		 5hwaA-3q3vA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 12 LEU A 175
GLY A 148
ASN A 144
TYR A 142
PHE A  18
 None
 1.25A 5kklB-3q3vA:
undetectable		 5kklB-3q3vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 9 ILE A  39
ALA A  42
ILE A  43
ILE A 112
LEU A  85
 None
 0.71A 5mvmA-3q3vA:
undetectable
5mvmE-3q3vA:
undetectable		 5mvmA-3q3vA:
10.95
5mvmE-3q3vA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3q3v PHOSPHOGLYCERATE
KINASE
(Campylobacter
jejuni) 		5 / 10 ILE A 112
LEU A  85
ILE A  39
ALA A  42
ILE A  43
 None
 0.72A 5mvmD-3q3vA:
undetectable
5mvmE-3q3vA:
undetectable		 5mvmD-3q3vA:
10.95
5mvmE-3q3vA:
10.95