SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		4 / 7 ILE A  19
GLY A  80
PHE A 109
ILE A 100
 None
 0.80A 2y7wC-3q3wA:
undetectable		 2y7wC-3q3wA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 PHE A 161
GLU A 144
ILE A 143
PHE A 154
ILE A 101
 None
 1.38A 3ndiA-3q3wA:
undetectable		 3ndiA-3q3wA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 HIS A   7
LEU A  92
GLY A  96
SER A  71
ALA A  99
 None
 0.96A 3sufA-3q3wA:
undetectable		 3sufA-3q3wA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		4 / 6 PHE A 109
ALA A  88
LEU A  92
VAL A  93
 None
 1.06A 4dubA-3q3wA:
undetectable		 4dubA-3q3wA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 LEU A  92
PHE A  79
PHE A 105
SER A 104
VAL A 128
 None
 1.25A 4eckA-3q3wA:
undetectable		 4eckA-3q3wA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		4 / 4 LEU A  92
ARG A  47
ILE A  24
PHE A  43
 None
 1.31A 5kirB-3q3wA:
undetectable		 5kirB-3q3wA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		5 / 12 HIS A   7
LEU A  92
GLY A  96
SER A  71
ALA A  99
 None
 0.95A 6c2mA-3q3wA:
undetectable		 6c2mA-3q3wA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 3q3w 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT
(Campylobacter
jejuni) 		5 / 10 GLY A 115
LEU A 114
SER A  71
HIS A 167
PHE A   4
 None
 1.49A 6gnfC-3q3wA:
undetectable		 6gnfC-3q3wA:
17.50