SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 9 LEU A  91
VAL A 287
GLY A 286
ALA A 291
LEU A 325
 None
 1.12A 1e7bA-3q41A:
undetectable		 1e7bA-3q41A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 LEU A  33
PHE A  42
ILE A  90
VAL A 334
VAL A 288
 None
 1.38A 1hrkB-3q41A:
3.8		 1hrkB-3q41A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 6 LEU A 119
ALA A  89
LEU A  91
SER A  64
 None
 0.99A 1tz8C-3q41A:
undetectable
1tz8D-3q41A:
undetectable		 1tz8C-3q41A:
16.71
1tz8D-3q41A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 6 LEU A  91
ALA A  62
LEU A  60
ALA A  49
 None
NAG  A 405 (-4.8A)
None
None
 0.96A 2vcvK-3q41A:
undetectable		 2vcvK-3q41A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 ALA A 291
LEU A 325
PHE A 340
THR A 140
GLY A 333
 None
 1.10A 2ve3A-3q41A:
undetectable		 2ve3A-3q41A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		3 / 3 GLU A 277
GLN A  40
ARG A  43
 None
 0.94A 2w3bB-3q41A:
2.2		 2w3bB-3q41A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 6 ARG A 359
LEU A 356
GLN A 357
LEU A 259
 None
 0.94A 3ag1C-3q41A:
undetectable
3ag1J-3q41A:
undetectable		 3ag1C-3q41A:
19.39
3ag1J-3q41A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 11 LEU A  33
PHE A  42
ILE A  90
VAL A 334
VAL A 288
 None
 1.42A 3aqiA-3q41A:
3.9		 3aqiA-3q41A:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 5 TYR A 109
THR A 110
PHE A 113
ARG A 115
 None
 0.23A 3qelC-3q41A:
50.8		 3qelC-3q41A:
82.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 ILE A  83
GLY A  30
ILE A 116
ASP A  81
LEU A  33
 None
 0.99A 3uj6A-3q41A:
undetectable		 3uj6A-3q41A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 ILE A  83
GLY A  30
ILE A 116
ASP A  81
LEU A  33
 None
 0.98A 3uj7B-3q41A:
undetectable		 3uj7B-3q41A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 LEU A  33
PHE A  42
ILE A  90
VAL A 334
VAL A 288
 None
 1.35A 3w1wB-3q41A:
3.9		 3w1wB-3q41A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 6 TYR A 351
GLN A 147
ARG A 124
GLU A 342
 None
 1.35A 4ax8A-3q41A:
3.6		 4ax8A-3q41A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 6 TYR A 351
GLN A 147
ARG A 124
GLU A 342
 None
 1.33A 4azvA-3q41A:
2.8		 4azvA-3q41A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 GLY A  30
ALA A  62
ASN A  61
ILE A  90
LEU A  33
 None
NAG  A 405 (-4.8A)
NAG  A 405 (-1.8A)
None
None
 1.23A 4azwA-3q41A:
2.5		 4azwA-3q41A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		3 / 3 PRO A 104
TYR A 128
GLY A 120
 None
 0.74A 4g2zA-3q41A:
undetectable		 4g2zA-3q41A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		5 / 12 GLY A 286
VAL A 287
LEU A  91
LEU A 138
ILE A 116
 None
 1.04A 4pd4C-3q41A:
undetectable		 4pd4C-3q41A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		6 / 9 ALA A 289
VAL A 292
LEU A 296
ILE A  26
ASN A  61
ALA A  49
 None
None
None
NAG  A 405 ( 4.1A)
NAG  A 405 (-1.8A)
None
 1.31A 5nunA-3q41A:
undetectable		 5nunA-3q41A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 8 PRO A 104
THR A 122
THR A 123
TYR A 128
 None
 1.35A 5x2sI-3q41A:
undetectable
5x2sJ-3q41A:
undetectable
5x2sK-3q41A:
undetectable		 5x2sI-3q41A:
17.16
5x2sJ-3q41A:
15.18
5x2sK-3q41A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 7 ALA A 111
THR A 110
TYR A 109
VAL A 118
 None
 0.88A 6cduA-3q41A:
undetectable
6cduE-3q41A:
undetectable		 6cduA-3q41A:
20.71
6cduE-3q41A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 8 VAL A 118
ALA A 111
THR A 110
TYR A 109
 None
 0.89A 6cduD-3q41A:
undetectable
6cduE-3q41A:
undetectable		 6cduD-3q41A:
20.71
6cduE-3q41A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3q41 GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
ZETA-1
(Rattus
norvegicus) 		4 / 7 VAL A 118
ALA A 111
THR A 110
TYR A 109
 None
 0.88A 6cduH-3q41A:
undetectable
6cduI-3q41A:
undetectable		 6cduH-3q41A:
20.71
6cduI-3q41A:
20.71