SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 111
TYR A 184
SER A 151
ASP A 109
 None
 1.49A 1vidA-3q48A:
undetectable		 1vidA-3q48A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 184
ILE A  99
LEU A 142
PHE A 143
 None
 1.25A 3ls4L-3q48A:
5.5		 3ls4L-3q48A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		5 / 9 ASN A 240
GLY A 238
GLY A 237
VAL A 232
ASP A 235
 None
 1.41A 5f8yA-3q48A:
undetectable		 5f8yA-3q48A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 111
TYR A 184
SER A 151
ASP A 109
 None
 1.45A 5fhrA-3q48A:
undetectable		 5fhrA-3q48A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_A_NIZA805_1
(CATALASE-PEROXIDASE)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		4 / 5 ARG A 244
TRP A 161
ALA A 156
PRO A 180
 None
 1.27A 5syiA-3q48A:
undetectable		 5syiA-3q48A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3q48 CHAPERONE CUPB2
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 111
VAL A 152
HIS A 242
THR A 181
 None
 1.38A 6dyoA-3q48A:
undetectable		 6dyoA-3q48A:
15.42