SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q4d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 8 GLY A 293
SER A 267
PHE A  51
HIS A  55
 DAL  A2472 ( 4.5A)
None
ALA  A2473 ( 4.6A)
None
 0.88A 1ax9A-3q4dA:
2.2		 1ax9A-3q4dA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 6 TYR A  45
GLY A  44
ASP A 108
GLY A 351
 None
 0.89A 1eswA-3q4dA:
2.4		 1eswA-3q4dA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 ASP A 108
GLY A 300
ALA A 275
ILE A 272
 None
 0.72A 1n49A-3q4dA:
undetectable		 1n49A-3q4dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 8 SER A  49
PHE A  51
ALA A  29
ASN A  31
 None
ALA  A2473 ( 4.6A)
None
None
 1.16A 1pnlA-3q4dA:
undetectable
1pnlB-3q4dA:
undetectable		 1pnlA-3q4dA:
20.45
1pnlB-3q4dA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 5 ILE A 212
ARG A 178
LEU A 207
PRO A 209
 None
 1.41A 1s8fA-3q4dA:
undetectable
1s8fB-3q4dA:
undetectable		 1s8fA-3q4dA:
18.73
1s8fB-3q4dA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 4 GLY A 293
SER A 267
ILE A  54
HIS A  55
 DAL  A2472 ( 4.5A)
None
None
None
 1.01A 1yajJ-3q4dA:
undetectable		 1yajJ-3q4dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 6 ALA A 308
PHE A 319
ILE A 334
VAL A 344
 None
 0.96A 2cizA-3q4dA:
undetectable		 2cizA-3q4dA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 LEU A 266
ILE A 314
ALA A 308
ALA A 304
LEU A 276
 None
 1.17A 2japC-3q4dA:
2.1		 2japC-3q4dA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 LEU A  23
ILE A  54
ALA A 250
ILE A 278
 None
 0.76A 2xkwA-3q4dA:
undetectable		 2xkwA-3q4dA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 9 THR A  53
ILE A  54
GLY A  24
PHE A  19
ILE A  21
 None
None
None
DAL  A2472 (-4.8A)
ALA  A2473 ( 4.8A)
 1.41A 2y7wA-3q4dA:
undetectable		 2y7wA-3q4dA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 8 ILE A  98
ASN A 103
SER A  85
SER A  96
 None
 1.11A 2zw9B-3q4dA:
undetectable		 2zw9B-3q4dA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		5 / 12 THR A 203
LEU A 207
GLY A 165
ILE A 189
ILE A  54
 None
 0.99A 3frqB-3q4dA:
undetectable		 3frqB-3q4dA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 9 ILE A 104
SER A 267
SER A  49
LEU A 299
SER A 297
 None
 1.48A 3ijxB-3q4dA:
0.0
3ijxD-3q4dA:
0.0		 3ijxB-3q4dA:
21.63
3ijxD-3q4dA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 6 LEU A 295
PRO A 322
GLU A 296
SER A 297
 None
 1.39A 3vlnA-3q4dA:
undetectable		 3vlnA-3q4dA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 5 PHE A  51
PHE A  19
ILE A  21
THR A 135
 ALA  A2473 ( 4.6A)
DAL  A2472 (-4.8A)
ALA  A2473 ( 4.8A)
DAL  A2472 (-3.6A)
 0.68A 4ejjC-3q4dA:
undetectable		 4ejjC-3q4dA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 279
ALA A 275
ALA A 303
GLY A 300
ALA A 308
 None
 1.13A 4enhA-3q4dA:
undetectable		 4enhA-3q4dA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 323
ILE A 334
THR A 132
GLY A 340
 None
 0.90A 4eq4A-3q4dA:
undetectable		 4eq4A-3q4dA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 323
ILE A 334
THR A 132
GLY A 340
 None
 0.95A 4eqlA-3q4dA:
undetectable		 4eqlA-3q4dA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 323
ILE A 334
THR A 132
GLY A 340
 None
 0.91A 4eqlB-3q4dA:
undetectable		 4eqlB-3q4dA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 6 LEU A 323
ILE A 334
THR A 132
GLY A 340
 None
 0.98A 4l39A-3q4dA:
2.6		 4l39A-3q4dA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		4 / 6 LEU A 359
TYR A   9
ILE A  43
GLY A 353
 None
 0.98A 4l39A-3q4dA:
2.6		 4l39A-3q4dA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 GLY A 353
HIS A 306
THR A 302
ILE A 334
VAL A 344
 None
 1.32A 4okwA-3q4dA:
undetectable		 4okwA-3q4dA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 6 LEU A 204
LEU A 207
GLU A 208
ILE A 212
 None
 0.92A 4ww7A-3q4dA:
undetectable		 4ww7A-3q4dA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  41
TYR A   9
PHE A 102
GLY A  66
THR A  38
 None
 1.20A 4zdyA-3q4dA:
undetectable		 4zdyA-3q4dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  41
TYR A   9
PHE A 102
GLY A  66
THR A  38
 None
 1.11A 4ze2A-3q4dA:
undetectable		 4ze2A-3q4dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 8 ALA A 352
VAL A 330
ALA A 303
GLY A 300
 None
 0.65A 4zjzA-3q4dA:
1.4		 4zjzA-3q4dA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  41
TYR A   9
PHE A 102
GLY A  66
THR A  38
 None
 1.12A 5eskA-3q4dA:
undetectable		 5eskA-3q4dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  41
TYR A   9
PHE A 102
GLY A  66
THR A  38
 None
 1.16A 5eslA-3q4dA:
undetectable		 5eslA-3q4dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 7 ILE A 342
HIS A 306
LEU A 309
ALA A 308
 None
 1.00A 5hrqE-3q4dA:
undetectable
5hrqF-3q4dA:
undetectable
5hrqJ-3q4dA:
undetectable		 5hrqE-3q4dA:
4.93
5hrqF-3q4dA:
6.49
5hrqJ-3q4dA:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.37A 5iqbA-3q4dA:
undetectable		 5iqbA-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 12 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.48A 5iqbD-3q4dA:
undetectable		 5iqbD-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 3q4d POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
(Cytophaga
hutchinsonii) 		5 / 11 ASP A 320
ASP A 133
SER A  49
GLU A 296
GLU A 216
 DAL  A2472 (-3.0A)
None
None
None
MG  A1602 (-3.1A)
 1.37A 5iqeA-3q4dA:
0.0		 5iqeA-3q4dA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		3 / 3 ASP A 241
ASN A 263
ASP A 318
 MG  A1602 ( 3.0A)
MG  A1602 ( 4.7A)
DAL  A2472 ( 2.4A)
 0.83A 5vopB-3q4dA:
6.4		 5vopB-3q4dA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  41
TYR A   9
PHE A 102
GLY A  66
THR A  38
 None
 1.13A 6e8qA-3q4dA:
undetectable		 6e8qA-3q4dA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3q4d MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY
POSSIBLE
CHLOROMUCONATE
CYCLOISOMERASE
(Cytophaga
hutchinsonii) 		4 / 7 ALA A 348
GLY A 349
LEU A 118
GLY A 332
 None
 0.83A 6nm4A-3q4dA:
undetectable		 6nm4A-3q4dA:
19.19