SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q4h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MIC_A_DVAA6_0 (GRAMICIDIN A)	3q4h	PE FAMILY PROTEIN LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7 (Mycolicibacteriu m smegmatis; Mycolicibacteriu m smegmatis)	3 / 3	ALA A 67 VAL A 65 TRP B 58	None	0.91A	1micA-3q4hA: undetectable 1micB-3q4hA: undetectable	1micA-3q4hA: 8.16 1micB-3q4hA: 8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_D_ROFD904_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3q4h	PE FAMILY PROTEIN LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7 (Mycolicibacteriu m smegmatis; Mycolicibacteriu m smegmatis)	3 / 3	ASN B 7 MET B 18 PHE A 42	None	0.83A	3g4lD-3q4hB: undetectable	3g4lD-3q4hB: 15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	3q4h	PE FAMILY PROTEIN LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7 (Mycolicibacteriu m smegmatis; Mycolicibacteriu m smegmatis)	4 / 8	MET B 62 ILE A 29 ARG A 26 TRP B 54	None	1.09A	4f4dB-3q4hB: undetectable	4f4dB-3q4hB: 14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZW4_A_SAMA302_0 (PUTATIVE O-METHYLTRANSFERASE YRRM)	3q4h	PE FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	GLU A 15 GLY A 77 ALA A 79 TYR A 83 ALA A 72	None	0.84A	5zw4A-3q4hA: undetectable	5zw4A-3q4hA: 18.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MIC_A_DVAA6_0","GRAMICIDIN A","3q4h","PE FAMILY PROTEIN;LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7","Mycolicibacterium smegmatis;Mycolicibacterium smegmatis",3,"ALA A  67;VAL A  65;TRP B  58","None","0.91A","1micA-3q4hA:undetectable;1micB-3q4hA:undetectable","1micA-3q4hA:8.16;1micB-3q4hA:8.16"],["3G4L_D_ROFD904_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3q4h","PE FAMILY PROTEIN;LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7","Mycolicibacterium smegmatis;Mycolicibacterium smegmatis",3,"ASN B   7;MET B  18;PHE A  42","None","0.83A","3g4lD-3q4hB:undetectable","3g4lD-3q4hB:15.75"],["4F4D_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","3q4h","PE FAMILY PROTEIN;LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7","Mycolicibacterium smegmatis;Mycolicibacterium smegmatis",4,"MET B  62;ILE A  29;ARG A  26;TRP B  54","None","1.09A","4f4dB-3q4hB:undetectable","4f4dB-3q4hB:14.56"],["5ZW4_A_SAMA302_0","PUTATIVE O-METHYLTRANSFERASE YRRM","3q4h","PE FAMILY PROTEIN","Mycolicibacterium smegmatis",5,"GLU A  15;GLY A  77;ALA A  79;TYR A  83;ALA A  72","None","0.84A","5zw4A-3q4hA:undetectable","5zw4A-3q4hA:18.05"]]