SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q4i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.00A 2eimP-3q4iA:
3.5
2eimW-3q4iA:
undetectable		 2eimP-3q4iA:
20.44
2eimW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.00A 2y69C-3q4iA:
3.5
2y69J-3q4iA:
undetectable		 2y69C-3q4iA:
20.44
2y69J-3q4iA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.03A 2y69P-3q4iA:
3.5
2y69W-3q4iA:
undetectable		 2y69P-3q4iA:
20.44
2y69W-3q4iA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.15A 3ablP-3q4iA:
3.5
3ablW-3q4iA:
undetectable		 3ablP-3q4iA:
20.44
3ablW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.97A 3abmC-3q4iA:
3.4
3abmJ-3q4iA:
undetectable		 3abmC-3q4iA:
20.44
3abmJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.03A 3abmP-3q4iA:
3.5
3abmW-3q4iA:
undetectable		 3abmP-3q4iA:
20.44
3abmW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.02A 3ag3C-3q4iA:
3.5
3ag3J-3q4iA:
undetectable		 3ag3C-3q4iA:
20.44
3ag3J-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		3 / 3 SER A 179
ASP A  70
ASP A 100
 None
 0.88A 3uj7A-3q4iA:
undetectable		 3uj7A-3q4iA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.95A 3wg7P-3q4iA:
3.5
3wg7W-3q4iA:
undetectable		 3wg7P-3q4iA:
20.44
3wg7W-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		5 / 12 ILE A 129
VAL A 108
ASP A  70
ILE A  71
GLU A 116
 None
None
None
None
GD3  A 301 (-3.1A)
 1.41A 4i41A-3q4iA:
undetectable		 4i41A-3q4iA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 148
ASP A 205
HIS A 135
THR A 184
 None
 1.25A 4paeA-3q4iA:
undetectable		 4paeA-3q4iA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.93A 5b1aC-3q4iA:
3.5
5b1aJ-3q4iA:
undetectable		 5b1aC-3q4iA:
20.44
5b1aJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		3 / 3 ASP A  70
GLU A 116
SER A 140
 None
GD3  A 301 (-3.1A)
None
 0.86A 5bw4B-3q4iA:
undetectable		 5bw4B-3q4iA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.99A 5wauC-3q4iA:
3.5
5wauJ-3q4iA:
undetectable		 5wauC-3q4iA:
20.44
5wauJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.00A 5wauc-3q4iA:
3.5
5wauj-3q4iA:
undetectable		 5wauc-3q4iA:
20.44
5wauj-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.81A 5x19C-3q4iA:
3.5
5x19J-3q4iA:
undetectable		 5x19C-3q4iA:
20.44
5x19J-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.02A 5xdqC-3q4iA:
3.6
5xdqJ-3q4iA:
undetectable		 5xdqC-3q4iA:
20.44
5xdqJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 5 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.01A 5xdqP-3q4iA:
3.5
5xdqW-3q4iA:
undetectable		 5xdqP-3q4iA:
20.44
5xdqW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.72A 5z84C-3q4iA:
3.6
5z84J-3q4iA:
undetectable		 5z84C-3q4iA:
20.44
5z84J-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.96A 5z84P-3q4iA:
3.5
5z84W-3q4iA:
undetectable		 5z84P-3q4iA:
20.44
5z84W-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.71A 5z85C-3q4iA:
3.5
5z85J-3q4iA:
undetectable		 5z85C-3q4iA:
20.44
5z85J-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.98A 5z85P-3q4iA:
3.5
5z85W-3q4iA:
undetectable		 5z85P-3q4iA:
20.44
5z85W-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.97A 5z86C-3q4iA:
3.6
5z86J-3q4iA:
undetectable		 5z86C-3q4iA:
20.44
5z86J-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.94A 5z86P-3q4iA:
3.5
5z86W-3q4iA:
undetectable		 5z86P-3q4iA:
20.44
5z86W-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.74A 5zcoC-3q4iA:
3.4
5zcoJ-3q4iA:
undetectable		 5zcoC-3q4iA:
20.44
5zcoJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 0.97A 5zcoP-3q4iA:
3.5
5zcoW-3q4iA:
undetectable		 5zcoP-3q4iA:
20.44
5zcoW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.01A 5zcpC-3q4iA:
3.5
5zcpJ-3q4iA:
undetectable		 5zcpC-3q4iA:
20.44
5zcpJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 6 PHE A 130
PHE A 148
LEU A  94
PHE A  83
 None
 1.01A 5zcpP-3q4iA:
3.5
5zcpW-3q4iA:
undetectable		 5zcpP-3q4iA:
20.44
5zcpW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.75A 5zcqC-3q4iA:
3.6
5zcqJ-3q4iA:
undetectable		 5zcqC-3q4iA:
20.44
5zcqJ-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		4 / 7 LEU A  81
PHE A  83
LEU A  94
PHE A 148
 None
 0.73A 5zcqP-3q4iA:
3.5
5zcqW-3q4iA:
undetectable		 5zcqP-3q4iA:
20.44
5zcqW-3q4iA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3q4i PHOSPHOHYDROLASE
(MUTT/NUDIX FAMILY
PROTEIN)
(Bacillus
cereus) 		3 / 3 TRP A  51
ILE A  38
ASP A  37
 None
 0.66A 6i0y7-3q4iA:
undetectable		 6i0y7-3q4iA:
7.07